TANIPLON

Details

Stereochemistry	ACHIRAL
Molecular Formula	C14H15N5O2
Molecular Weight	285.3012
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

COC1=NC2=NC(=CN2C3=C1CCCC3)C4=NOC(C)=N4

InChI

InChIKey=OYKONKGGKFFMDV-UHFFFAOYSA-N

InChI=1S/C14H15N5O2/c1-8-15-12(18-21-8)10-7-19-11-6-4-3-5-9(11)13(20-2)17-14(19)16-10/h7H,3-6H2,1-2H3

HIDE SMILES / InChI

Molecular Formula	C14H15N5O2
Molecular Weight	285.3012
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Description
Sources: https://www.ncbi.nlm.nih.gov/pubmed/1648620 | https://adisinsight.springer.com/drugs/800003284

Taniplon (also known as RU 33543), a potential anxiolytic agent that binds to benzodiazepine sites on the GABAA receptor. This drug was studied on the preclinical stage in France for the treatment of anxiety disorders. However, the further development of taniplon was discontinued.

Originator

Approval Year

PubMed

Title	Date	PubMed
2-(oxadiazolyl)- and 2-(thiazolyl)imidazo[1,2-a]pyrimidines as agonists and inverse agonists at benzodiazepine receptors.	1991-07	1648620

Patents

Substance Class	Chemical Created by `admin` on `Mon Mar 31 18:32:01 GMT 2025` Edited by `admin` on `Mon Mar 31 18:32:01 GMT 2025`
Record UNII	OKS0I0BBLP
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

taniplon [INN]

Preferred Name

English

TANIPLON

Official Name

English

Classification Tree Code System Code

NCI_THESAURUS

C29756