U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

Approval Year

Substance Class Protein
Created
by admin
on Sat Dec 16 14:08:17 GMT 2023
Edited
by admin
on Sat Dec 16 14:08:17 GMT 2023
Protein Type MONOCLONAL ANTIBODY
Protein Sub Type IGG4
Sequence Origin HUMANIZED MOUSE
Sequence Type COMPLETE
Record UNII
OI8P0SFD4R
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
IERAMILIMAB
INN   USAN  
Official Name English
ieramilimab [INN]
Common Name English
LAG-525
Code English
LAG 525 [WHO-DD]
Common Name English
LAG525
Code English
IERAMILIMAB [USAN]
Common Name English
ANTI-LAG-3 MONOCLONAL ANTIBODY LAG525
Common Name English
IMMUNOGLOBULIN G4-KAPPA, ANTI-(HOMO SAPIENS LAG3 (LYMPHOCYTE ACTIVATING 3, LYMPHOCYTE-ACTIVATION 3, CD223)), HUMANIZED MONOCLONAL ANTIBODY; GAMMA4 HEAVY CHAIN HUMANIZED (1-451) (VH (HOMO SAPIENS IGHV7-4-1*02 (85.7%)-(IGHD)-IGHJ4*01 (92.3%)) (8.8.18) (1-1
Common Name English
HUMANISED IMP-701
Common Name English
NVP-LAG525
Code English
Classification Tree Code System Code
NCI_THESAURUS C134305
Created by admin on Sat Dec 16 14:08:18 GMT 2023 , Edited by admin on Sat Dec 16 14:08:18 GMT 2023
Code System Code Type Description
NCI_THESAURUS
C122683
Created by admin on Sat Dec 16 14:08:18 GMT 2023 , Edited by admin on Sat Dec 16 14:08:18 GMT 2023
PRIMARY
CAS
2072080-18-1
Created by admin on Sat Dec 16 14:08:18 GMT 2023 , Edited by admin on Sat Dec 16 14:08:18 GMT 2023
NO STRUCTURE GIVEN
WIKIPEDIA
Ieramilimab
Created by admin on Sat Dec 16 14:08:18 GMT 2023 , Edited by admin on Sat Dec 16 14:08:18 GMT 2023
PRIMARY
FDA UNII
OI8P0SFD4R
Created by admin on Sat Dec 16 14:08:18 GMT 2023 , Edited by admin on Sat Dec 16 14:08:18 GMT 2023
PRIMARY
USAN
JK-98
Created by admin on Sat Dec 16 14:08:18 GMT 2023 , Edited by admin on Sat Dec 16 14:08:18 GMT 2023
PRIMARY
INN
11005
Created by admin on Sat Dec 16 14:08:18 GMT 2023 , Edited by admin on Sat Dec 16 14:08:18 GMT 2023
PRIMARY
CAS
2137049-37-5
Created by admin on Sat Dec 16 14:08:18 GMT 2023 , Edited by admin on Sat Dec 16 14:08:18 GMT 2023
PRIMARY
From To
1_22 1_96
1_139 3_214
1_152 1_208
1_231 2_231
1_234 2_234
1_266 1_326
1_372 1_430
2_22 2_96
2_139 4_214
2_152 2_208
2_266 2_326
2_372 2_430
3_23 3_88
3_134 3_194
4_23 4_88
4_134 4_194
Glycosylation Type MAMMALIAN
Glycosylation Link Type Site
N 1_302
N 2_302
Related Record Type Details
TARGET -> INHIBITOR
Related Record Type Details
ACTIVE MOIETY
Name Property Type Amount Referenced Substance Defining Parameters References
MOL_WEIGHT:NUMBER(CALCULATED) CHEMICAL
Molecular Formula CHEMICAL