U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

Approval Year

Substance Class Protein
Created
by admin
on Sat Dec 16 15:18:12 GMT 2023
Edited
by admin
on Sat Dec 16 15:18:12 GMT 2023
Protein Type MONOCLONAL ANTIBODY
Protein Sub Type IGG1
Sequence Origin HUMAN
Sequence Type COMPLETE
Record UNII
OHZ2MEL7FD
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
TOZORAKIMAB
USAN   INN  
Official Name English
MEDI-3506
Code English
MEDI 3506 [WHO-DD]
Common Name English
MEDI3506
Code English
TOZORAKIMAB [USAN]
Common Name English
Immunoglobulin G1-lambda2, anti-[Homo sapiens IL33 (interleukin 33, DVS27, NF-HEV, IL1F11)], monoclonal antibody; gamma1 heavy chain (1-456) [VH (Homo sapiens IGHV3-23*01 (93.9%) -(IGHD) -IGHJ4*01 (85.7%) L123>M (121)) CDR-IMGT [8.8.19] (26-33.51-58.97-1
Common Name English
tozorakimab [INN]
Common Name English
Immunoglobulin G1, anti-(human interleukin 33) (human monoclonal MEDI3506 γ1-chain), disulfide with human monoclonal MEDI3506 λ-chain, dimer
Common Name English
Code System Code Type Description
INN
11647
Created by admin on Sat Dec 16 15:18:12 GMT 2023 , Edited by admin on Sat Dec 16 15:18:12 GMT 2023
PRIMARY INN
USAN
KL-47
Created by admin on Sat Dec 16 15:18:12 GMT 2023 , Edited by admin on Sat Dec 16 15:18:12 GMT 2023
PRIMARY
NCI_THESAURUS
C179129
Created by admin on Sat Dec 16 15:18:12 GMT 2023 , Edited by admin on Sat Dec 16 15:18:12 GMT 2023
PRIMARY
CAS
2376858-66-9
Created by admin on Sat Dec 16 15:18:12 GMT 2023 , Edited by admin on Sat Dec 16 15:18:12 GMT 2023
PRIMARY
FDA UNII
OHZ2MEL7FD
Created by admin on Sat Dec 16 15:18:12 GMT 2023 , Edited by admin on Sat Dec 16 15:18:12 GMT 2023
PRIMARY
From To
1_22 1_96
2_22 2_96
2_153 2_209
2_229 4_211
2_270 2_330
1_153 1_209
2_376 2_434
3_22 3_87
3_134 3_193
4_22 4_87
4_134 4_193
1_229 3_211
1_235 2_235
1_238 2_238
1_270 1_330
1_376 1_434
Glycosylation Type MAMMALIAN
Glycosylation Link Type Site
N 1_306
N 2_306
Related Record Type Details
TARGET -> INHIBITOR
TARGET->LIGAND
Related Record Type Details
ACTIVE MOIETY
Name Property Type Amount Referenced Substance Defining Parameters References
Molecular Formula CHEMICAL
MOL_WEIGHT:NUMBER(CALCULATED) CHEMICAL