Details
| Stereochemistry | ACHIRAL |
| Molecular Formula | C5H3ClN4 |
| Molecular Weight | 154.557 |
| Optical Activity | NONE |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
ClC1=NC=NC2=C1N=CN2
InChI
InChIKey=ZKBQDFAWXLTYKS-UHFFFAOYSA-N
InChI=1S/C5H3ClN4/c6-4-3-5(9-1-7-3)10-2-8-4/h1-2H,(H,7,8,9,10)
| Molecular Formula | C5H3ClN4 |
| Molecular Weight | 154.557 |
| Charge | 0 |
| Count |
|
| Stereochemistry | ACHIRAL |
| Additional Stereochemistry | No |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Optical Activity | NONE |
Approval Year
PubMed
| Title | Date | PubMed |
|---|---|---|
| Purine analogs as potential anticytomegalovirus agents. | 1969 Sep |
|
| Structure-activity relationships for the binding of ligands to xanthine or guanine phosphoribosyl-transferase from Toxoplasma gondii. | 1995 Nov 9 |
|
| 5'-O-alkyl ethers of N,2-substituted adenosine derivatives: partial agonists for the adenosine A1 and A3 receptors. | 2001 Aug 30 |
|
| Synthesis and biological evaluation of novel thioapio dideoxynucleosides. | 2002 May |
|
| Nucleic acid related compounds. 118. Nonaqueous diazotization of aminopurine derivatives. Convenient access to 6-halo- and 2,6-dihalopurine nucleosides and 2'-deoxynucleosides with acyl or silyl halides. | 2003 Jan 24 |
|
| Introduction of a benzyl group onto the 2'-OH of 6-chloropurine 3'-O-benzoylriboside. | 2003 May-Aug |
|
| Synthesis and Ca2+-mobilizing activity of purine-modified mimics of adenophostin A: a model for the adenophostin-Ins(1,4,5)P3 receptor interaction. | 2003 Nov 6 |
|
| Molecular design of novel spin-labeled nucleosides directly attached base moiety. | 2004 |
|
| Asymmetric synthesis of novel thioiso dideoxynucleosides with exocyclic methylene as potential antiviral agents. | 2004 Apr 30 |
|
| Transition-metal-mediated synthesis of novel carbocyclic nucleoside analogues with antitumoral activity. | 2004 Oct 11 |
|
| The novel pyrimidine and purine derivatives of l-ascorbic acid: synthesis, one- and two-dimensional 1H and 13C NMR study, cytostatic and antiviral evaluation. | 2005 Jan 3 |
|
| Traceless solid-phase synthesis of N1,N7-disubstituted purines. | 2005 Sep-Oct |
|
| De novo asymmetric synthesis of homoadenosine via a palladium-catalyzed N-glycosylation. | 2006 Jan 19 |
|
| Synthesis of fluorinated nucleosides. | 2006 Jul |
|
| A synthetic route to 9-(polyhydroxyalkyl)purines. | 2006 Sep 25 |
|
| Synthesis and anti-HCV activity Of 2''-beta-hydroxymethylated nucleosides. | 2007 |
|
| Palladium-catalyzed cross-coupling reactions in c6 modifications of purine nucleosides. | 2007 Mar |
|
| Neo-clinicians, clinical trials, and the reorganization of medical research in Paris hospitals after the Second World War: the trajectory of Jean Bernard. | 2008 Oct |
|
| Synthesis, characterization and biological activity of ring-substituted 6-benzylamino-9-tetrahydropyran-2-yl and 9-tetrahydrofuran-2-ylpurine derivatives. | 2009 Mar 1 |
|
| Activation of IP(3) receptors by synthetic bisphosphate ligands. | 2009 Mar 14 |
|
| Additive Pummerer reaction of 3,5-O-(di-tert-butyl)silylene-4-thiofuranoid glycal: a high-yield and beta-selective entry to 4'-thioribonucleosides. | 2009 Mar 20 |
|
| Synthesis of modified homo-N-nucleosides from the reactions of mesityl nitrile oxide with 9-allylpurines and their influence on lipid peroxidation and thrombin inhibition. | 2009 Nov 15 |
|
| Symmetrical and unsymmetrical alpha,omega-nucleobase amide-conjugated systems. | 2010 Apr 12 |
|
| Microwave-assisted syntheses of nucleosides and their precursors. | 2010 Feb |
|
| Semisynthesis of 6-chloropurine-2'-deoxyriboside 5'-dimethoxytrityl 3'-(2-cyanoethyl-N,N-diisopropylamino)phosphoramidite and its use in the synthesis of fluorescently labeled oligonucleotides. | 2010 Nov |
|
| DNA oligomers containing site-specific and stereospecific exocyclic deoxyadenosine adducts of 1,2,3,4-diepoxybutane: synthesis, characterization, and effects on DNA structure. | 2010 Oct 18 |
Patents
| Substance Class |
Chemical
Created
by
admin
on
Edited
Fri Dec 15 15:04:01 GMT 2023
by
admin
on
Fri Dec 15 15:04:01 GMT 2023
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| Record UNII |
OH8700156W
|
| Record Status |
Validated (UNII)
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| Record Version |
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m3433
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OH8700156W
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