BISPHENOL AF

OC1=CC=C(C=C1)C(C2=CC=C(O)C=C2)(C(F)(F)F)C(F)(F)F

InChIKey=ZFVMWEVVKGLCIJ-UHFFFAOYSA-N

InChI=1S/C15H10F6O2/c16-14(17,18)13(15(19,20)21,9-1-5-11(22)6-2-9)10-3-7-12(23)8-4-10/h1-8,22-23H

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

PubMed

Title	Date	PubMed
Bisphenol AF stimulates transcription and secretion of C-X-C chemokine ligand 12 to promote proliferation of cultured T47D breast cancer cells.	2015-12-02	26435001
Genome-wide gene expression profiling of low-dose, long-term exposure of human osteosarcoma cells to bisphenol A and its analogs bisphenols AF and S.	2015-08	25912373
Bioactivation of bisphenol A and its analogs (BPF, BPAF, BPZ and DMBPA) in human liver microsomes.	2013-06	23470418
Bisphenol A affects androgen receptor function via multiple mechanisms.	2013-05-25	23562765
Biotransformation of bisphenol AF to its major glucuronide metabolite reduces estrogenic activity.	2013	24349450
Bisphenol AF may cause testosterone reduction by directly affecting testis function in adult male rats.	2012-06-01	22504055
Bisphenol AF is a full agonist for the estrogen receptor ERalpha but a highly specific antagonist for ERbeta.	2010-09	20427257
Development of a molecularly imprinted polymer for selective extraction of bisphenol A in water samples.	2010-06	20405487
1,1,1,3,3,3-Hexafluoro-2,2-bis-[4-(4-nitro-phen-oxy)phen-yl]propane.	2008-07-19	21203242
Prediction of estrogen receptor agonists and characterization of associated molecular descriptors by statistical learning methods.	2006-11	16497524
Comparison of the reporter gene assay for ER-alpha antagonists with the immature rat uterotrophic assay of 10 chemicals.	2003-04-30	12765246
Measurement of estrogenic activity of chemicals for the development of new dental polymers.	2001-09-22	11566573

Patents

Substance Class	Chemical Created by `admin` on `Mon Mar 31 19:25:57 GMT 2025` Edited by `admin` on `Mon Mar 31 19:25:57 GMT 2025`
Record UNII	OH7IX8A37J
Record Status	`Validated (UNII)`
Record Version

Name

Type

Language

BISPHENOL AF

Common Name

English

CURATIVE 30

Preferred Name

English

1,1,1,3,3,3-HEXAFLUORO-2,2-BIS(4-HYDROXYPHENYL)PROPANE

Systematic Name

English

2,2-BIS(4-HYDROXYPHENYL)HEXAFLUOROPROPANE

Systematic Name

English

NSC-152522

Code

English

HEXAFLUOROBISPHENOL A

Systematic Name

English

2,2-BIS(4'-HYDROXYPHENYL)HEXAFLUOROPROPANE

Common Name

English

Code System Code Type Description

WIKIPEDIA

BISPHENOL AF