BISPHENOL AF

Details

Stereochemistry	ACHIRAL
Molecular Formula	C15H10F6O2
Molecular Weight	336.2291
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

OC1=CC=C(C=C1)C(C2=CC=C(O)C=C2)(C(F)(F)F)C(F)(F)F

InChI

InChIKey=ZFVMWEVVKGLCIJ-UHFFFAOYSA-N

InChI=1S/C15H10F6O2/c16-14(17,18)13(15(19,20)21,9-1-5-11(22)6-2-9)10-3-7-12(23)8-4-10/h1-8,22-23H

HIDE SMILES / InChI

Molecular Formula	C15H10F6O2
Molecular Weight	336.2291
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Approval Year

PubMed

Title	Date	PubMed
Measurement of estrogenic activity of chemicals for the development of new dental polymers.	2001 Aug-Oct	11566573
Comparison of the reporter gene assay for ER-alpha antagonists with the immature rat uterotrophic assay of 10 chemicals.	2003 Apr 30	12765246
Prediction of estrogen receptor agonists and characterization of associated molecular descriptors by statistical learning methods.	2006 Nov	16497524
1,1,1,3,3,3-Hexafluoro-2,2-bis-[4-(4-nitro-phen-oxy)phen-yl]propane.	2008 Jul 19	21203242
Development of a molecularly imprinted polymer for selective extraction of bisphenol A in water samples.	2010 Jun	20405487
Bisphenol AF is a full agonist for the estrogen receptor ERalpha but a highly specific antagonist for ERbeta.	2010 Sep	20427257
Bisphenol AF may cause testosterone reduction by directly affecting testis function in adult male rats.	2012 Jun 1	22504055
Biotransformation of bisphenol AF to its major glucuronide metabolite reduces estrogenic activity.	2013	24349450
Bioactivation of bisphenol A and its analogs (BPF, BPAF, BPZ and DMBPA) in human liver microsomes.	2013 Jun	23470418
Bisphenol A affects androgen receptor function via multiple mechanisms.	2013 May 25	23562765
Genome-wide gene expression profiling of low-dose, long-term exposure of human osteosarcoma cells to bisphenol A and its analogs bisphenols AF and S.	2015 Aug	25912373
Bisphenol AF stimulates transcription and secretion of C-X-C chemokine ligand 12 to promote proliferation of cultured T47D breast cancer cells.	2015 Dec 2	26435001

Patents

Substance Class	Chemical Created by `admin` on `Fri Dec 15 18:54:48 GMT 2023` Edited by `admin` on `Fri Dec 15 18:54:48 GMT 2023`
Record UNII	OH7IX8A37J
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

BISPHENOL AF

Common Name

English

CURATIVE 30

Brand Name

English

1,1,1,3,3,3-HEXAFLUORO-2,2-BIS(4-HYDROXYPHENYL)PROPANE

Systematic Name

English

2,2-BIS(4-HYDROXYPHENYL)HEXAFLUOROPROPANE

Systematic Name

English

NSC-152522

Code

English

HEXAFLUOROBISPHENOL A

Systematic Name

English

2,2-BIS(4'-HYDROXYPHENYL)HEXAFLUOROPROPANE

Common Name

English

Code System Code Type Description

WIKIPEDIA

BISPHENOL AF