Details
| Stereochemistry | ACHIRAL |
| Molecular Formula | 2C7H5O3.Sr |
| Molecular Weight | 361.85 |
| Optical Activity | NONE |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
[Sr++].OC1=C(C=CC=C1)C([O-])=O.OC2=C(C=CC=C2)C([O-])=O
InChI
InChIKey=BJTJYQIAHXROJC-UHFFFAOYSA-L
InChI=1S/2C7H6O3.Sr/c2*8-6-4-2-1-3-5(6)7(9)10;/h2*1-4,8H,(H,9,10);/q;;+2/p-2
| Molecular Formula | C7H5O3 |
| Molecular Weight | 137.1128 |
| Charge | -1 |
| Count |
|
| Stereochemistry | ACHIRAL |
| Additional Stereochemistry | No |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Optical Activity | NONE |
| Molecular Formula | Sr |
| Molecular Weight | 87.62 |
| Charge | 2 |
| Count |
|
| Stereochemistry | ACHIRAL |
| Additional Stereochemistry | No |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Optical Activity | NONE |
Approval Year
Doses
| Dose | Population | Adverse events |
|---|---|---|
1.3 g 1 times / hour multiple, oral Dose: 1.3 g, 1 times / hour Route: oral Route: multiple Dose: 1.3 g, 1 times / hour Co-administed with:: sodium bicarbonate(1.3 g; 1/hour) Sources: |
unhealthy, 12-48 n = 29 Health Status: unhealthy Condition: inflammatory condition (rheumatic fever, tonsillitis, and endocarditis mainly) Age Group: 12-48 Sex: M+F Population Size: 29 Sources: |
Disc. AE: Nausea and vomiting, Nausea... Other AEs: Diaphoresis, Diaphoresis... AEs leading to discontinuation/dose reduction: Nausea and vomiting (2%) Other AEs:Nausea (slight, 2%) Nausea (marked, 1%) Nausea (21%) Diaphoresis (marked, 3%) Sources: Diaphoresis (slight, 3%) Deafness (2%) Tinnitus (marked, 2%) Tinnitus (slight, 2%) Deafness (1%) Deafness (2%) Deafness (1%) Delirium (slight, 4%) Delirium (marked, 1%) Hyperactive delirium (1%) Delirium (1%) |
AEs
| AE | Significance | Dose | Population |
|---|---|---|---|
| Deafness | 1% | 1.3 g 1 times / hour multiple, oral Dose: 1.3 g, 1 times / hour Route: oral Route: multiple Dose: 1.3 g, 1 times / hour Co-administed with:: sodium bicarbonate(1.3 g; 1/hour) Sources: |
unhealthy, 12-48 n = 29 Health Status: unhealthy Condition: inflammatory condition (rheumatic fever, tonsillitis, and endocarditis mainly) Age Group: 12-48 Sex: M+F Population Size: 29 Sources: |
| Deafness | 1% | 1.3 g 1 times / hour multiple, oral Dose: 1.3 g, 1 times / hour Route: oral Route: multiple Dose: 1.3 g, 1 times / hour Co-administed with:: sodium bicarbonate(1.3 g; 1/hour) Sources: |
unhealthy, 12-48 n = 29 Health Status: unhealthy Condition: inflammatory condition (rheumatic fever, tonsillitis, and endocarditis mainly) Age Group: 12-48 Sex: M+F Population Size: 29 Sources: |
| Delirium | 1% | 1.3 g 1 times / hour multiple, oral Dose: 1.3 g, 1 times / hour Route: oral Route: multiple Dose: 1.3 g, 1 times / hour Co-administed with:: sodium bicarbonate(1.3 g; 1/hour) Sources: |
unhealthy, 12-48 n = 29 Health Status: unhealthy Condition: inflammatory condition (rheumatic fever, tonsillitis, and endocarditis mainly) Age Group: 12-48 Sex: M+F Population Size: 29 Sources: |
| Hyperactive delirium | 1% | 1.3 g 1 times / hour multiple, oral Dose: 1.3 g, 1 times / hour Route: oral Route: multiple Dose: 1.3 g, 1 times / hour Co-administed with:: sodium bicarbonate(1.3 g; 1/hour) Sources: |
unhealthy, 12-48 n = 29 Health Status: unhealthy Condition: inflammatory condition (rheumatic fever, tonsillitis, and endocarditis mainly) Age Group: 12-48 Sex: M+F Population Size: 29 Sources: |
| Deafness | 2% | 1.3 g 1 times / hour multiple, oral Dose: 1.3 g, 1 times / hour Route: oral Route: multiple Dose: 1.3 g, 1 times / hour Co-administed with:: sodium bicarbonate(1.3 g; 1/hour) Sources: |
unhealthy, 12-48 n = 29 Health Status: unhealthy Condition: inflammatory condition (rheumatic fever, tonsillitis, and endocarditis mainly) Age Group: 12-48 Sex: M+F Population Size: 29 Sources: |
| Deafness | 2% | 1.3 g 1 times / hour multiple, oral Dose: 1.3 g, 1 times / hour Route: oral Route: multiple Dose: 1.3 g, 1 times / hour Co-administed with:: sodium bicarbonate(1.3 g; 1/hour) Sources: |
unhealthy, 12-48 n = 29 Health Status: unhealthy Condition: inflammatory condition (rheumatic fever, tonsillitis, and endocarditis mainly) Age Group: 12-48 Sex: M+F Population Size: 29 Sources: |
| Nausea and vomiting | 2% Disc. AE |
1.3 g 1 times / hour multiple, oral Dose: 1.3 g, 1 times / hour Route: oral Route: multiple Dose: 1.3 g, 1 times / hour Co-administed with:: sodium bicarbonate(1.3 g; 1/hour) Sources: |
unhealthy, 12-48 n = 29 Health Status: unhealthy Condition: inflammatory condition (rheumatic fever, tonsillitis, and endocarditis mainly) Age Group: 12-48 Sex: M+F Population Size: 29 Sources: |
| Nausea | 21% Disc. AE |
1.3 g 1 times / hour multiple, oral Dose: 1.3 g, 1 times / hour Route: oral Route: multiple Dose: 1.3 g, 1 times / hour Co-administed with:: sodium bicarbonate(1.3 g; 1/hour) Sources: |
unhealthy, 12-48 n = 29 Health Status: unhealthy Condition: inflammatory condition (rheumatic fever, tonsillitis, and endocarditis mainly) Age Group: 12-48 Sex: M+F Population Size: 29 Sources: |
| Delirium | marked, 1% | 1.3 g 1 times / hour multiple, oral Dose: 1.3 g, 1 times / hour Route: oral Route: multiple Dose: 1.3 g, 1 times / hour Co-administed with:: sodium bicarbonate(1.3 g; 1/hour) Sources: |
unhealthy, 12-48 n = 29 Health Status: unhealthy Condition: inflammatory condition (rheumatic fever, tonsillitis, and endocarditis mainly) Age Group: 12-48 Sex: M+F Population Size: 29 Sources: |
| Nausea | marked, 1% Disc. AE |
1.3 g 1 times / hour multiple, oral Dose: 1.3 g, 1 times / hour Route: oral Route: multiple Dose: 1.3 g, 1 times / hour Co-administed with:: sodium bicarbonate(1.3 g; 1/hour) Sources: |
unhealthy, 12-48 n = 29 Health Status: unhealthy Condition: inflammatory condition (rheumatic fever, tonsillitis, and endocarditis mainly) Age Group: 12-48 Sex: M+F Population Size: 29 Sources: |
| Tinnitus | marked, 2% | 1.3 g 1 times / hour multiple, oral Dose: 1.3 g, 1 times / hour Route: oral Route: multiple Dose: 1.3 g, 1 times / hour Co-administed with:: sodium bicarbonate(1.3 g; 1/hour) Sources: |
unhealthy, 12-48 n = 29 Health Status: unhealthy Condition: inflammatory condition (rheumatic fever, tonsillitis, and endocarditis mainly) Age Group: 12-48 Sex: M+F Population Size: 29 Sources: |
| Diaphoresis | marked, 3% | 1.3 g 1 times / hour multiple, oral Dose: 1.3 g, 1 times / hour Route: oral Route: multiple Dose: 1.3 g, 1 times / hour Co-administed with:: sodium bicarbonate(1.3 g; 1/hour) Sources: |
unhealthy, 12-48 n = 29 Health Status: unhealthy Condition: inflammatory condition (rheumatic fever, tonsillitis, and endocarditis mainly) Age Group: 12-48 Sex: M+F Population Size: 29 Sources: |
| Tinnitus | slight, 2% | 1.3 g 1 times / hour multiple, oral Dose: 1.3 g, 1 times / hour Route: oral Route: multiple Dose: 1.3 g, 1 times / hour Co-administed with:: sodium bicarbonate(1.3 g; 1/hour) Sources: |
unhealthy, 12-48 n = 29 Health Status: unhealthy Condition: inflammatory condition (rheumatic fever, tonsillitis, and endocarditis mainly) Age Group: 12-48 Sex: M+F Population Size: 29 Sources: |
| Nausea | slight, 2% Disc. AE |
1.3 g 1 times / hour multiple, oral Dose: 1.3 g, 1 times / hour Route: oral Route: multiple Dose: 1.3 g, 1 times / hour Co-administed with:: sodium bicarbonate(1.3 g; 1/hour) Sources: |
unhealthy, 12-48 n = 29 Health Status: unhealthy Condition: inflammatory condition (rheumatic fever, tonsillitis, and endocarditis mainly) Age Group: 12-48 Sex: M+F Population Size: 29 Sources: |
| Diaphoresis | slight, 3% | 1.3 g 1 times / hour multiple, oral Dose: 1.3 g, 1 times / hour Route: oral Route: multiple Dose: 1.3 g, 1 times / hour Co-administed with:: sodium bicarbonate(1.3 g; 1/hour) Sources: |
unhealthy, 12-48 n = 29 Health Status: unhealthy Condition: inflammatory condition (rheumatic fever, tonsillitis, and endocarditis mainly) Age Group: 12-48 Sex: M+F Population Size: 29 Sources: |
| Delirium | slight, 4% | 1.3 g 1 times / hour multiple, oral Dose: 1.3 g, 1 times / hour Route: oral Route: multiple Dose: 1.3 g, 1 times / hour Co-administed with:: sodium bicarbonate(1.3 g; 1/hour) Sources: |
unhealthy, 12-48 n = 29 Health Status: unhealthy Condition: inflammatory condition (rheumatic fever, tonsillitis, and endocarditis mainly) Age Group: 12-48 Sex: M+F Population Size: 29 Sources: |
| Substance Class |
Chemical
Created
by
admin
on
Edited
Fri Dec 15 15:00:46 GMT 2023
by
admin
on
Fri Dec 15 15:00:46 GMT 2023
|
| Record UNII |
OGF9EV99TC
|
| Record Status |
Validated (UNII)
|
| Record Version |
|
-
Download
| Name | Type | Language | ||
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Systematic Name | English | ||
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Common Name | English |
| Code System | Code | Type | Description | ||
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2045402
Created by
admin on Fri Dec 15 15:00:46 GMT 2023 , Edited by admin on Fri Dec 15 15:00:46 GMT 2023
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DTXSID10890499
Created by
admin on Fri Dec 15 15:00:46 GMT 2023 , Edited by admin on Fri Dec 15 15:00:46 GMT 2023
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OGF9EV99TC
Created by
admin on Fri Dec 15 15:00:46 GMT 2023 , Edited by admin on Fri Dec 15 15:00:46 GMT 2023
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CHEMBL2107280
Created by
admin on Fri Dec 15 15:00:46 GMT 2023 , Edited by admin on Fri Dec 15 15:00:46 GMT 2023
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OGF9EV99TC
Created by
admin on Fri Dec 15 15:00:46 GMT 2023 , Edited by admin on Fri Dec 15 15:00:46 GMT 2023
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208-386-4
Created by
admin on Fri Dec 15 15:00:46 GMT 2023 , Edited by admin on Fri Dec 15 15:00:46 GMT 2023
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526-26-1
Created by
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54684619
Created by
admin on Fri Dec 15 15:00:46 GMT 2023 , Edited by admin on Fri Dec 15 15:00:46 GMT 2023
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PRIMARY |
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