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Details

Stereochemistry ACHIRAL
Molecular Formula C16H12N2
Molecular Weight 232.2799
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of CRYPTOLEPINE

SMILES

CN1C2=C3C=CC=CC3=NC2=CC4=CC=CC=C14

InChI

InChIKey=KURWKDDWCJELSV-UHFFFAOYSA-N
InChI=1S/C16H12N2/c1-18-15-9-5-2-6-11(15)10-14-16(18)12-7-3-4-8-13(12)17-14/h2-10H,1H3

HIDE SMILES / InChI

Molecular Formula C16H12N2
Molecular Weight 232.2799
Charge 0
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Approval Year

Targets

Targets

Primary TargetPharmacologyConditionPotency
PubMed

PubMed

TitleDatePubMed
Cryptolepine and quindoline: understanding their photophysics.
2017 Apr 19
In vitro anti-malarial interaction and gametocytocidal activity of cryptolepine.
2017 Dec 28
Cryptolepine inhibits melanoma cell growth through coordinated changes in mitochondrial biogenesis, dynamics and metabolic tumor suppressor AMPKα1/2-LKB1.
2017 May 4
Cryptolepine and aromathecin based mimics as potent G-quadruplex-binding, DNA-cleavage and anticancer agents: Design, synthesis and DNA targeting-induced apoptosis.
2019 May 1
Substance Class Chemical
Created
by admin
on Fri Dec 15 17:59:29 GMT 2023
Edited
by admin
on Fri Dec 15 17:59:29 GMT 2023
Record UNII
OF1UIT4RDH
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
CRYPTOLEPINE
Common Name English
5H-QUINDOLINE, 5-METHYL-
Common Name English
Code System Code Type Description
CAS
480-26-2
Created by admin on Fri Dec 15 17:59:29 GMT 2023 , Edited by admin on Fri Dec 15 17:59:29 GMT 2023
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FDA UNII
OF1UIT4RDH
Created by admin on Fri Dec 15 17:59:29 GMT 2023 , Edited by admin on Fri Dec 15 17:59:29 GMT 2023
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EPA CompTox
DTXSID6037645
Created by admin on Fri Dec 15 17:59:29 GMT 2023 , Edited by admin on Fri Dec 15 17:59:29 GMT 2023
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PUBCHEM
82143
Created by admin on Fri Dec 15 17:59:29 GMT 2023 , Edited by admin on Fri Dec 15 17:59:29 GMT 2023
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WIKIPEDIA
Cryptolepine
Created by admin on Fri Dec 15 17:59:29 GMT 2023 , Edited by admin on Fri Dec 15 17:59:29 GMT 2023
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Related Record Type Details
METABOLITE -> PARENT