U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

Approval Year

Substance Class Protein
Created
by admin
on Sat Dec 16 15:15:50 GMT 2023
Edited
by admin
on Sat Dec 16 15:15:50 GMT 2023
Protein Type BISPECIFIC ANTIBODY
Protein Sub Type T-CELL-ENGAGER
Sequence Origin HUMANIZED MOUSE
Sequence Type COMPLETE
Record UNII
ODG03B9M4U
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
Xaluritamig
INN  
Official Name English
Immunoglobulin G1 Fab fragment [218-lysine], anti-(human metalloproteinase STEAP1) (human-Mus musculus clone 2F3.013 N67Q γ1-chain) fusion protein with peptide linker (GGGGS)2 fusion protein with immunoglobulin anti-(human CD3 antigen) (human-Mus muscul
Common Name English
immunoglobulin G1-scFv-CH/G1-kappa, anti-[Homo sapiens STEAP1 (STEAP family member 1, six transmembrane epithelial antigen of the prostate 1, STEAP1 metalloreductase) and anti-[Homo sapiens CD3, bispecific, trivalent
Common Name English
xaluritamig [INN]
Common Name English
Classification Tree Code System Code
FDA ORPHAN DRUG 760020
Created by admin on Sat Dec 16 15:15:50 GMT 2023 , Edited by admin on Sat Dec 16 15:15:50 GMT 2023
Code System Code Type Description
FDA UNII
ODG03B9M4U
Created by admin on Sat Dec 16 15:15:50 GMT 2023 , Edited by admin on Sat Dec 16 15:15:50 GMT 2023
PRIMARY
INN
12082
Created by admin on Sat Dec 16 15:15:50 GMT 2023 , Edited by admin on Sat Dec 16 15:15:50 GMT 2023
PRIMARY
CAS
2559056-68-5
Created by admin on Sat Dec 16 15:15:50 GMT 2023 , Edited by admin on Sat Dec 16 15:15:50 GMT 2023
PRIMARY
From To
1_22 1_96
1_148 1_204
1_503 2_230
1_506 2_233
1_643 1_701
2_22 2_96
2_148 2_204
2_370 2_428
3_23 3_87
3_133 3_193
4_23 4_87
4_133 4_193
1_224 3_213
1_256 1_332
1_401 1_469
1_537 1_578
1_568 1_597
2_224 4_213
2_264 2_305
2_295 2_324
Related Record Type Details
ACTIVE MOIETY
Name Property Type Amount Referenced Substance Defining Parameters References
MOL_WEIGHT:NUMBER(CALCULATED) CHEMICAL
Molecular Formula CHEMICAL