Perenostobart

U.S. Department of Health & Human Services Divider Arrow

National Institutes of Health Divider Arrow

NCATS

Approval Year

Substance Class	Protein Created by `admin` on `Wed Apr 02 05:16:26 GMT 2025` Edited by `admin` on `Wed Apr 02 05:16:26 GMT 2025`
Protein Type	MONOCLONAL ANTIBODY
Protein Sub Type	IGG4
Sequence Origin	HUMAN
Sequence Type	COMPLETE
Record UNII	O84ZK2F68E
Record Status	`Validated (UNII)`
Record Version

Download

Name

Type

Language

SRF-617

Preferred Name

English

Perenostobart

Official Name

English

Immunoglobulin G4 [229-proline], anti-(human ectonucleoside triphosphate diphosphohydrolase 1) (human monoclonal SRF617 ?4-chain), disulfide with human monoclonal SRF617 ?-chain, dimer

Common Name

English

immunoglobulin G4-kappa, anti-[ENTPD1(ectonucleoside triphosphate diphosphohydrolase 1, NTPDase-1, ATPDase, SPG64, CD39)], Homo sapiens monoclonal antibody

Common Name

English

SRF 617 [WHO-DD]

Common Name

English

perenostobart [INN]

Common Name

English

Classification Tree Code System Code

FDA ORPHAN DRUG

808821

Created by admin on Wed Apr 02 05:16:26 GMT 2025 , Edited by admin on Wed Apr 02 05:16:26 GMT 2025

Code System Code Type Description

INN

12269

Created by admin on Wed Apr 02 05:16:26 GMT 2025 , Edited by admin on Wed Apr 02 05:16:26 GMT 2025

PRIMARY

CAS

2643331-31-9

Created by admin on Wed Apr 02 05:16:26 GMT 2025 , Edited by admin on Wed Apr 02 05:16:26 GMT 2025

PRIMARY

SMS_ID

300000046874

Created by admin on Wed Apr 02 05:16:26 GMT 2025 , Edited by admin on Wed Apr 02 05:16:26 GMT 2025

PRIMARY

NCI_THESAURUS

C171450

Created by admin on Wed Apr 02 05:16:26 GMT 2025 , Edited by admin on Wed Apr 02 05:16:26 GMT 2025

PRIMARY

FDA UNII

O84ZK2F68E

Created by admin on Wed Apr 02 05:16:26 GMT 2025 , Edited by admin on Wed Apr 02 05:16:26 GMT 2025

PRIMARY

From	To
1_22	1_96
2_22	2_96
2_135	4_214
2_148	2_204
2_262	2_322
1_135	3_214
2_368	2_426
3_23	3_88
3_134	3_194
4_23	4_88
4_134	4_194
1_148	1_204
1_227	2_227
1_230	2_230
1_262	1_322
1_368	1_426

Glycosylation Type

MAMMALIAN

Glycosylation Link Type	Site
N	1_298
N	2_298

Related Record Type Details


					K72T3FS567

ADENOSINE

TARGET->INHIBITOR OF EXPRESSION

Comments:

Reduces the production of adenosine

Amount:

Related Record Type Details


					O84ZK2F68E

ACTIVE MOIETY

Amount:

Structural Modifications

Modification Type	Location Site	Location Type	Residue Modified	Extent	Fragment Name	Fragment Approval
AMINO_ACID_SUBSTITUTION	[1_1] [2_1]	N-TERMINUS		Amount:	PIDOLIC ACID	SZB83O1W42
AMINO ACID REMOVAL	[1_448] [2_448]	C-TERMINUS		Amount:	LYSINE	K3Z4F929H6

Name	Property Type	Amount	Referenced Substance	Defining	Parameters	References
MOL_WEIGHT:NUMBER(CALCULATED)	CHEMICAL
Molecular Formula	CHEMICAL