3,5-DICHLOROSALICYLIC ACID

OC(=O)C1=CC(Cl)=CC(Cl)=C1O

InChIKey=CNJGWCQEGROXEE-UHFFFAOYSA-N

InChI=1S/C7H4Cl2O3/c8-3-1-4(7(11)12)6(10)5(9)2-3/h1-2,10H,(H,11,12)

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

PubMed

Title	Date	PubMed
Structure-based optimization and biological evaluation of human 20α-hydroxysteroid dehydrogenase (AKR1C1) salicylic acid-based inhibitors.	2010-11	20850205
Correlation of binding constants and molecular modelling of inhibitors in the active sites of aldose reductase and aldehyde reductase.	2009-02-01	19121944
Structure of aldehyde reductase in ternary complex with coenzyme and the potent 20alpha-hydroxysteroid dehydrogenase inhibitor 3,5-dichlorosalicylic acid: implications for inhibitor binding and selectivity.	2008-11-01	18782556
Selectivity determinants of inhibitor binding to human 20alpha-hydroxysteroid dehydrogenase: crystal structure of the enzyme in ternary complex with coenzyme and the potent inhibitor 3,5-dichlorosalicylic acid.	2008-08-14	18620380
Identification of a cytochrome P450 cDNA (CYP98A5) from Phaseolus vulgaris, inducible by 3,5-dichlorosalicylic acid and 2,6-dichloro isonicotinic acid.	2007-04	16584810
Salicylic acid, an ambimobile molecule exhibiting a high ability to accumulate in the phloem.	2006-08	16778012
Salicylate activity. 3. Structure relationship to systemic acquired resistance.	2005-12-14	16332130
Guest-controlling effects on ER behaviors of beta-cyclodextrin polymer.	2005-09-01	16009217
Biochemical and molecular characterization of a ring fission dioxygenase with the ability to oxidize (substituted) salicylate(s) from Pseudaminobacter salicylatoxidans.	2004-09-03	15220336

Patents

Substance Class	Chemical Created by `admin` on `Mon Mar 31 22:23:18 GMT 2025` Edited by `admin` on `Mon Mar 31 22:23:18 GMT 2025`
Record UNII	O6PXR32G3V
Record Status	`Validated (UNII)`
Record Version

Name

Type

Language

3,5-DICHLOROSALICYLIC ACID

Systematic Name

English

NSC-30109

Preferred Name

English

3,5-DICHLOROSALICYCLIC ACID

Common Name

English

3,5-DICHLORO-2-HYDROXYBENZOIC ACID

Systematic Name

English

SALICYLIC ACID, 3,5-DICHLORO-

Systematic Name

English

BENZOIC ACID, 3,5-DICHLORO-2-HYDROXY-

Systematic Name

English

2-HYDROXY-3,5-DICHLOROBENZOIC ACID [HSDB]

Common Name

English

Code System Code Type Description

ECHA (EC/EINECS)

206-281-8