ACETERGAMINE

Details

Stereochemistry	ABSOLUTE
Molecular Formula	C18H23N3O
Molecular Weight	297.3947
Optical Activity	UNSPECIFIED
Defined Stereocenters	3 / 3
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

[H][C@@]12CC3=CNC4=CC=CC(=C34)[C@@]1([H])C[C@@H](CNC(C)=O)CN2C

InChI

InChIKey=SGZVEWGAZGOWGP-XGWLTEMNSA-N

InChI=1S/C18H23N3O/c1-11(22)19-8-12-6-15-14-4-3-5-16-18(14)13(9-20-16)7-17(15)21(2)10-12/h3-5,9,12,15,17,20H,6-8,10H2,1-2H3,(H,19,22)/t12-,15+,17+/m0/s1

HIDE SMILES / InChI

Molecular Formula	C18H23N3O
Molecular Weight	297.3947
Charge	0
Count

Stereochemistry	ABSOLUTE
Additional Stereochemistry	No
Defined Stereocenters	3 / 3
E/Z Centers	0
Optical Activity	UNSPECIFIED

Description
Sources: https://books.google.ru/books?id=0vXTBwAAQBAJ&pg=PA4&lpg=PA4&dq=ACETERGAMINE retrieved from The Dictionary of Drugs: Chemical Data. Chemical Data, Structures and Bibliographies. Editors: Elks, J., p.4 | https://www.ncbi.nlm.nih.gov/pubmed/15233578

Acetergamine is a derivative of ergoline, it is an oxytocic agent. Acetergamine is alpha-1 blocker and vasodilator. It has been investigated as a treatment for cerebellar ataxia.

Approval Year

PubMed

Title	Date	PubMed
Pharmacological treatments of cerebellar ataxia.	2004	15233578

Patents

Sample Use Guides

In Vivo Use Guide

LD50 40 mg/kg i.v. rabbit

Route of Administration: Intravenous

Substance Class	Chemical Created by `admin` on `Sat Dec 16 17:28:31 GMT 2023` Edited by `admin` on `Sat Dec 16 17:28:31 GMT 2023`
Record UNII	O60O0JB93O
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

ACETERGAMINE

Official Name

English

acetergamine [INN]

Common Name

English

(+)-N-ACETYL-9,10-DIHYDROLYSERGAMINE

Common Name

English

Classification Tree Code System Code

NCI_THESAURUS

C66885