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Details

Stereochemistry ABSOLUTE
Molecular Formula C18H23N3O
Molecular Weight 297.3947
Optical Activity UNSPECIFIED
Defined Stereocenters 3 / 3
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of ACETERGAMINE

SMILES

[H][C@@]12CC3=CNC4=CC=CC(=C34)[C@@]1([H])C[C@@H](CNC(C)=O)CN2C

InChI

InChIKey=SGZVEWGAZGOWGP-XGWLTEMNSA-N
InChI=1S/C18H23N3O/c1-11(22)19-8-12-6-15-14-4-3-5-16-18(14)13(9-20-16)7-17(15)21(2)10-12/h3-5,9,12,15,17,20H,6-8,10H2,1-2H3,(H,19,22)/t12-,15+,17+/m0/s1

HIDE SMILES / InChI

Molecular Formula C18H23N3O
Molecular Weight 297.3947
Charge 0
Count
MOL RATIO 1 MOL RATIO (average)
Stereochemistry ABSOLUTE
Additional Stereochemistry No
Defined Stereocenters 3 / 3
E/Z Centers 0
Optical Activity UNSPECIFIED

Description

Acetergamine is a derivative of ergoline, it is an oxytocic agent. Acetergamine is alpha-1 blocker and vasodilator. It has been investigated as a treatment for cerebellar ataxia.

Approval Year

PubMed

Sample Use Guides

In Vivo Use Guide
LD50 40 mg/kg i.v. rabbit
Route of Administration: Intravenous
Substance Class Chemical
Record UNII
O60O0JB93O
Record Status Validated (UNII)
Record Version