NICAMETATE HYDROCHLORIDE

Details

Stereochemistry	ACHIRAL
Molecular Formula	C12H18N2O2.ClH
Molecular Weight	258.744
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

Cl.CCN(CC)CCOC(=O)C1=CN=CC=C1

InChI

InChIKey=FESGALSVBLWWKR-UHFFFAOYSA-N

InChI=1S/C12H18N2O2.ClH/c1-3-14(4-2)8-9-16-12(15)11-6-5-7-13-10-11;/h5-7,10H,3-4,8-9H2,1-2H3;1H

HIDE SMILES / InChI

Molecular Formula	C12H18N2O2
Molecular Weight	222.2835
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Molecular Formula	ClH
Molecular Weight	36.461
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Description
Sources: http://www.yusheng.com.tw/english/ysc002_Circulatory.html
Curator's Comment: Description was created based on several sources, including https://books.google.ru/books?id=tsjrCAAAQBAJ&pg=PA197&lpg=PA197&dq=NICAMETATE+Vasodilator&source=bl&ots=R3SvlIMrz9&sig=fjPfKUUS4rtrYtdKqukxERpMUBE&hl=en&sa=X&ved=0ahUKEwiWzsuTz-nOAhUGJpoKHdq9AOkQ6AEINjAF#v=onepage&q=NICAMETATE%20Vasodilator&f=false (retrieved from Concise Dictionary of Pharmacological Agents: Properties and Synonyms By I.K. Morton, Judith M. Hall, p.197

Nicametate is a vasodilator, which enhances blood flow and oxygen to the brain, aids stroke recovery. It also can use for treating intermittent claudication in certain patients.

Approval Year

Targets

Primary Target	Pharmacology	Condition	Potency
cell growth 21 Target ID: GO:0016049 Sources: http://www.ncbi.nlm.nih.gov/pubmed/9700242	Inhibitor 8504

Conditions

Condition	Modality	Targets	Highest Phase	Product
Vascular pathology 2 Sources: http://www.ncbi.nlm.nih.gov/pubmed/5079565	Primary		Preclinical	Unknown Approved Use Unknown
Cardiovascular diseases 72 Sources: http://www.ncbi.nlm.nih.gov/pubmed/4211730	Primary		Preclinical	Unknown Approved Use Unknown

PubMed

Title	Date	PubMed
Is higher serum total cholesterol level associated with better long-term functional outcomes after noncardioembolic ischemic stroke?	2010-06	20510983

Patents

Sample Use Guides

In Vivo Use Guide

300 mg of nicametate citrate daily

Route of Administration: Oral

In Vitro Use Guide

Unknown

Substance Class	Chemical Created by `admin` on `Mon Mar 31 22:45:20 GMT 2025` Edited by `admin` on `Mon Mar 31 22:45:20 GMT 2025`
Record UNII	O42P8SO5U6
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

NICAMETATE HYDROCHLORIDE [MI]

Preferred Name

English

NICAMETATE HYDROCHLORIDE

Common Name

English

3-PYRIDINECARBOXYLIC ACID, 2-(DIETHYLAMINO)ETHYL ESTER, HYDROCHLORIDE (1:1)

Systematic Name

English

3-PYRIDINECARBOXYLIC ACID 2-(DIETHYLAMINO)ETHYL ESTER, HYDROCHLORIDE

Systematic Name

English

Code System Code Type Description

CAS

56676-64-3