Details
| Stereochemistry | ABSOLUTE |
| Molecular Formula | C9H12BNO4.ClH |
| Molecular Weight | 245.468 |
| Optical Activity | UNSPECIFIED |
| Defined Stereocenters | 1 / 1 |
| E/Z Centers | 0 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
Cl.N[C@@H](CC1=CC=C(C=C1)B(O)O)C(O)=O
InChI
InChIKey=ITAYDCRFNXQNBL-QRPNPIFTSA-N
InChI=1S/C9H12BNO4.ClH/c11-8(9(12)13)5-6-1-3-7(4-2-6)10(14)15;/h1-4,8,14-15H,5,11H2,(H,12,13);1H/t8-;/m0./s1
| Molecular Formula | C9H12BNO4 |
| Molecular Weight | 209.007 |
| Charge | 0 |
| Count |
|
| Stereochemistry | ABSOLUTE |
| Additional Stereochemistry | No |
| Defined Stereocenters | 1 / 1 |
| E/Z Centers | 0 |
| Optical Activity | UNSPECIFIED |
| Molecular Formula | ClH |
| Molecular Weight | 36.461 |
| Charge | 0 |
| Count |
|
| Stereochemistry | ACHIRAL |
| Additional Stereochemistry | No |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Optical Activity | NONE |
Approval Year
PubMed
| Title | Date | PubMed |
|---|---|---|
| The hamster cheek pouch as a model of oral cancer for boron neutron capture therapy studies: selective delivery of boron by boronophenylalanine. | 2001 Dec 15 |
|
| Boron neutron capture therapy for the treatment of oral cancer in the hamster cheek pouch model. | 2001 Dec 15 |
|
| Biodistribution of a carborane-containing porphyrin as a targeting agent for Boron Neutron Capture Therapy of oral cancer in the hamster cheek pouch. | 2003 Mar |
|
| Boron neutron capture therapy of brain tumors: clinical trials at the finnish facility using boronophenylalanine. | 2003 Mar-Apr |
|
| Rat brain tumor models to assess the efficacy of boron neutron capture therapy: a critical evaluation. | 2003 Mar-Apr |
|
| Effectiveness of BNCT for recurrent head and neck malignancies. | 2004 Nov |
|
| The effect of dexamethasone on the uptake of p-boronophenylalanine in the rat brain and intracranial 9L gliosarcoma. | 2004 Nov |
|
| Homogeneous boron targeting of heterogeneous tumors for boron neutron capture therapy (BNCT): chemical analyses in the hamster cheek pouch oral cancer model. | 2006 Oct |
|
| Early effects of boron neutron capture therapy on rat glioma models. | 2007 |
|
| Molecular targeting and treatment of an epidermal growth factor receptor-positive glioma using boronated cetuximab. | 2007 Feb 15 |
|
| Therapeutic effect of boron neutron capture therapy (BNCT) on field cancerized tissue: inhibition of DNA synthesis and lag in the development of second primary tumors in precancerous tissue around treated tumors in DMBA-induced carcinogenesis in the hamster cheek pouch oral cancer model. | 2007 Mar |
|
| Role of p53 mutation in the effect of boron neutron capture therapy on oral squamous cell carcinoma. | 2009 Dec 11 |
|
| In vitro neutron irradiation of glioma and endothelial cultured cells. | 2009 Jul |
|
| Calculations of dose distributions in the lungs of a rat model irradiated in the thermal column of the TRIGA reactor in Pavia. | 2009 Jul |
|
| Selective uptake of p-boronophenylalanine by osteosarcoma cells for boron neutron capture therapy. | 2009 Jul |
|
| Feasibility of boron neutron capture therapy for malignant spinal tumors. | 2009 Jul |
|
| Boron neutron capture therapy (BNCT) inhibits tumor development from precancerous tissue: an experimental study that supports a potential new application of BNCT. | 2009 Jul |
|
| Boronophenylalanine uptake in C6 glioma model is dramatically increased by L-DOPA preloading. | 2009 Jul |
|
| Aryl boronic acid inhibition of synthetic melanin polymerization. | 2010 Aug 1 |
|
| Boron neutron capture therapy induces apoptosis of glioma cells through Bcl-2/Bax. | 2010 Dec 2 |
| Substance Class |
Chemical
Created
by
admin
on
Edited
Sat Dec 16 01:06:17 GMT 2023
by
admin
on
Sat Dec 16 01:06:17 GMT 2023
|
| Record UNII |
O37300B3AP
|
| Record Status |
Validated (UNII)
|
| Record Version |
|
-
Download
| Name | Type | Language | ||
|---|---|---|---|---|
|
Systematic Name | English | ||
|
Systematic Name | English | ||
|
Brand Name | English | ||
|
Systematic Name | English | ||
|
Common Name | English | ||
|
Common Name | English |
| Code System | Code | Type | Description | ||
|---|---|---|---|---|---|
|
O37300B3AP
Created by
admin on Sat Dec 16 01:06:17 GMT 2023 , Edited by admin on Sat Dec 16 01:06:17 GMT 2023
|
PRIMARY | |||
|
71423166
Created by
admin on Sat Dec 16 01:06:17 GMT 2023 , Edited by admin on Sat Dec 16 01:06:17 GMT 2023
|
PRIMARY | |||
|
DTXSID30227243
Created by
admin on Sat Dec 16 01:06:17 GMT 2023 , Edited by admin on Sat Dec 16 01:06:17 GMT 2023
|
PRIMARY | |||
|
76410-59-8
Created by
admin on Sat Dec 16 01:06:17 GMT 2023 , Edited by admin on Sat Dec 16 01:06:17 GMT 2023
|
PRIMARY |
| Related Record | Type | Details | ||
|---|---|---|---|---|
|
|
PARENT -> SALT/SOLVATE |
