Details
| Stereochemistry | ABSOLUTE |
| Molecular Formula | C9H12BNO4.ClH |
| Molecular Weight | 245.468 |
| Optical Activity | UNSPECIFIED |
| Defined Stereocenters | 1 / 1 |
| E/Z Centers | 0 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
Cl.N[C@@H](CC1=CC=C(C=C1)B(O)O)C(O)=O
InChI
InChIKey=ITAYDCRFNXQNBL-QRPNPIFTSA-N
InChI=1S/C9H12BNO4.ClH/c11-8(9(12)13)5-6-1-3-7(4-2-6)10(14)15;/h1-4,8,14-15H,5,11H2,(H,12,13);1H/t8-;/m0./s1
| Molecular Formula | C9H12BNO4 |
| Molecular Weight | 209.007 |
| Charge | 0 |
| Count |
|
| Stereochemistry | ABSOLUTE |
| Additional Stereochemistry | No |
| Defined Stereocenters | 1 / 1 |
| E/Z Centers | 0 |
| Optical Activity | UNSPECIFIED |
| Molecular Formula | ClH |
| Molecular Weight | 36.461 |
| Charge | 0 |
| Count |
|
| Stereochemistry | ACHIRAL |
| Additional Stereochemistry | No |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Optical Activity | NONE |
Approval Year
PubMed
| Title | Date | PubMed |
|---|---|---|
| Boron neutron capture therapy: effects of split dose and overall treatment time. | 2001 Apr |
|
| The hamster cheek pouch as a model of oral cancer for boron neutron capture therapy studies: selective delivery of boron by boronophenylalanine. | 2001 Dec 15 |
|
| The early successful treatment of glioblastoma patients with modified boron neutron capture therapy. Report of two cases. | 2003 Nov |
|
| Delivery of (10)boron to oral squamous cell carcinoma using boronophenylalanine and borocaptate sodium for boron neutron capture therapy. | 2004 May |
|
| Effectiveness of BNCT for recurrent head and neck malignancies. | 2004 Nov |
|
| Boronated epidermal growth factor as a delivery agent for neutron capture therapy of EGF receptor positive gliomas. | 2004 Nov |
|
| Radiobiology of BNCT mediated by GB-10 and GB-10+BPA in experimental oral cancer. | 2004 Nov |
|
| Boron-containing nucleosides as potential delivery agents for neutron capture therapy of brain tumors. | 2004 Sep 1 |
|
| Impact of intra-arterial administration of boron compounds on dose-volume histograms in boron neutron capture therapy for recurrent head-and-neck tumors. | 2006 Dec 1 |
|
| Pharmacokinetic study of BSH and BPA in simultaneous use for BNCT. | 2006 Jul |
|
| Homogeneous boron targeting of heterogeneous tumors for boron neutron capture therapy (BNCT): chemical analyses in the hamster cheek pouch oral cancer model. | 2006 Oct |
|
| Comments to article: Henriksson R et al., Boron neutron capture therapy (BNCT) for glioblastoma multiforme: a phase II study evaluating a prolonged high-dose of boronophenylalanine (BPA) Radiother Oncol (2008). | 2008 Aug |
|
| Role of p53 mutation in the effect of boron neutron capture therapy on oral squamous cell carcinoma. | 2009 Dec 11 |
|
| Boron neutron capture therapy for newly diagnosed glioblastoma. | 2009 Jan |
|
| In vitro neutron irradiation of glioma and endothelial cultured cells. | 2009 Jul |
|
| Calculations of dose distributions in the lungs of a rat model irradiated in the thermal column of the TRIGA reactor in Pavia. | 2009 Jul |
|
| Selective uptake of p-boronophenylalanine by osteosarcoma cells for boron neutron capture therapy. | 2009 Jul |
|
| Planned fractionated boron neutron capture therapy using epithermal neutrons for a patient with recurrent squamous cell carcinoma in the temporal bone: a case report. | 2009 Mar |
|
| Insight into the mechanisms underlying tumor response to boron neutron capture therapy in the hamster cheek pouch oral cancer model. | 2009 May |
|
| Aryl boronic acid inhibition of synthetic melanin polymerization. | 2010 Aug 1 |
|
| Boron neutron capture therapy induces apoptosis of glioma cells through Bcl-2/Bax. | 2010 Dec 2 |
|
| Early effect of boron neutron capture therapy mediated by boronophenylalanine (BPA-BNCT) on mast cells in premalignant tissue and tumors of the hamster cheek pouch. | 2010 May |
| Substance Class |
Chemical
Created
by
admin
on
Edited
Sat Dec 16 01:06:17 GMT 2023
by
admin
on
Sat Dec 16 01:06:17 GMT 2023
|
| Record UNII |
O37300B3AP
|
| Record Status |
Validated (UNII)
|
| Record Version |
|
-
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O37300B3AP
Created by
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71423166
Created by
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DTXSID30227243
Created by
admin on Sat Dec 16 01:06:17 GMT 2023 , Edited by admin on Sat Dec 16 01:06:17 GMT 2023
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76410-59-8
Created by
admin on Sat Dec 16 01:06:17 GMT 2023 , Edited by admin on Sat Dec 16 01:06:17 GMT 2023
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PARENT -> SALT/SOLVATE |
