GOLOCDACIMAB

U.S. Department of Health & Human Services Divider Arrow

National Institutes of Health Divider Arrow

NCATS

Approval Year

Substance Class	Protein Created by `admin` on `Tue Apr 01 23:02:28 GMT 2025` Edited by `admin` on `Tue Apr 01 23:02:28 GMT 2025`
Protein Type	MONOCLONAL ANTIBODY
Protein Sub Type	IGG1\|LAMDA
Sequence Origin	HUMAN
Sequence Type	COMPLETE
Record UNII	O27K1DC15D
Record Status	`Validated (UNII)`
Record Version

Download

Name

Type

Language

MEDI-6570

Preferred Name

English

GOLOCDACIMAB

Official Name

English

golocdacimab [INN]

Common Name

English

IMMUNOGLOBULIN G1 (246-PHENYLALANINE,247-GLUTAMIC ACID,343-SERINE), ANTI-(HUMAN LECTIN-LIKE OXIDIZED LOW-DENSITY LIPOPROTEIN RECEPTOR 1) (HUMAN MONOCLONAL MEDI6570 .GAMMA.1-CHAIN), DISULFIDE WITH HUMAN MONOCLONAL MEDI6570 .LAMBDA.-CHAIN, DIMER

Common Name

English

HUMAN IgG1 LAMBDA ANTI LECTIN-LIKE OXIDISED LOW-DENSITY LIPOPROTEIN RECEPTOR MONOCLONAL ANTIBODY MEDI6570

Common Name

English

MEDI6570

Code

English

Code System Code Type Description

SMS_ID

300000023260

Created by admin on Tue Apr 01 23:02:28 GMT 2025 , Edited by admin on Tue Apr 01 23:02:28 GMT 2025

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CAS

2418540-63-1

Created by admin on Tue Apr 01 23:02:28 GMT 2025 , Edited by admin on Tue Apr 01 23:02:28 GMT 2025

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INN

12003

Created by admin on Tue Apr 01 23:02:28 GMT 2025 , Edited by admin on Tue Apr 01 23:02:28 GMT 2025

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FDA UNII

O27K1DC15D

Created by admin on Tue Apr 01 23:02:28 GMT 2025 , Edited by admin on Tue Apr 01 23:02:28 GMT 2025

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NCI_THESAURUS

C188607

Created by admin on Tue Apr 01 23:02:28 GMT 2025 , Edited by admin on Tue Apr 01 23:02:28 GMT 2025

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From	To
1_22	1_96
2_22	2_96
3_22	3_90
4_22	4_90
1_156	1_212
2_156	2_212
3_139	3_198
4_139	4_198
1_232	3_216
2_232	4_216
1_238	2_238
1_241	2_241
1_273	1_333
1_379	1_437
2_273	2_333
2_379	2_437

Glycosylation Type

MAMMALIAN

Glycosylation Link Type	Site
N	1_309
N	2_309

Related Record Type Details


					O27K1DC15D

ACTIVE MOIETY

Amount:

Structural Modifications

Modification Type	Location Site	Location Type	Residue Modified	Extent	Fragment Name	Fragment Approval
AMINO_ACID_SUBSTITUTION	[1_1] [2_1]	N-TERMINUS			PIDOLIC ACID	SZB83O1W42
AMINO ACID REMOVAL	[1_459] [2_459]	C-TERMINUS			LYSINE	K3Z4F929H6

Name	Property Type	Amount	Referenced Substance	Defining	Parameters	References
MOL_WEIGHT:NUMBER(CALCULATED)	CHEMICAL
Molecular Formula	CHEMICAL