DIOSPYRIN

CC1=CC2=C(C(=O)C=C(C2=O)C3=C(O)C4=C(C=C3C)C(=O)C=CC4=O)C(O)=C1

InChIKey=WRFTYMHHWSAKSK-UHFFFAOYSA-N

InChI=1S/C22H14O6/c1-9-5-12-19(16(25)6-9)17(26)8-13(21(12)27)18-10(2)7-11-14(23)3-4-15(24)20(11)22(18)28/h3-8,25,28H,1-2H3

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

PubMed

Title	Date	PubMed
Effects of atovaquone and diospyrin-based drugs on ubiquinone biosynthesis in Pneumocystis carinii organisms.	2000 Jan	10602716
Inhibition of drug-sensitive and drug-resistant strains of Mycobacterium tuberculosis by diospyrin, isolated from Euclea natalensis.	2001 Dec	11694367
Antimycobacterial activity of diospyrin derivatives and a structural analogue of diospyrin against Mycobacterium tuberculosis in vitro.	2003 Feb	12562718
Antitubercular and antibacterial activity of quinonoid natural products against multi-drug resistant clinical isolates.	2014 Jul	24318724

Patents

Substance Class	Chemical Created by `admin` on `Fri Dec 15 17:03:05 GMT 2023` Edited by `admin` on `Fri Dec 15 17:03:05 GMT 2023`
Record UNII	O0IQZ8B2R7
Record Status	`Validated (UNII)`
Record Version

Name

Type

Language

DIOSPYRIN

Common Name

English

EUCLEIN

Common Name

English

(2,2'-BINAPHTHALENE)-1,4,5',8'-TETRONE, 1',5-DIHYDROXY-3',7-DIMETHYL-

Systematic Name

English

NSC-208730

Code

English

Code System Code Type Description

PUBCHEM

308140