TIZABRIN

Details

Stereochemistry	ABSOLUTE
Molecular Formula	C8H15NO3S
Molecular Weight	205.275
Optical Activity	UNSPECIFIED
Defined Stereocenters	3 / 3
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

C[C@@H]1C[S@@+]([O-])C(C)(C)[C@@H](N1)C(O)=O

InChI

InChIKey=GBNFAIIPJQPAHF-KATQCZMTSA-N

InChI=1S/C8H15NO3S/c1-5-4-13(12)8(2,3)6(9-5)7(10)11/h5-6,9H,4H2,1-3H3,(H,10,11)/t5-,6+,13-/m1/s1

HIDE SMILES / InChI

Molecular Formula	C8H15NO3S
Molecular Weight	205.275
Charge	0
Count

Stereochemistry	ABSOLUTE
Additional Stereochemistry	No
Defined Stereocenters	2 / 2
E/Z Centers	0
Optical Activity	UNSPECIFIED

Description
Sources: Hansch, C. et al. (1990) Comprehensive Medicinal Chemistry, page 497, retrieved from: https://books.google.ru/books?id=swltAAAAMAAJ | Elks, J. (2014) The Dictionary of Drugs: Chemical Data, page 1210, retrieved from: https://books.google.ru/books?id=0vXTBwAAQBAJ

Tizabrin is the antithrombotic, fibrinolytic agent. Tizabrin (CP-2129) stimulates fibrinolysis after intravenous administration in human volunteers due to an increase in tissue plasminogen activator (t-PA) activity. Tizabrin has no intrinsic fibrinolytic activity in vitro.

Approval Year

Substance Class	Chemical Created by `admin` on `Fri Dec 15 15:45:55 GMT 2023` Edited by `admin` on `Fri Dec 15 15:45:55 GMT 2023`
Record UNII	O066WUI46I
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

TIZABRIN

Official Name

English

tizabrin [INN]

Common Name

English

(1R,3S,5R)-2,2,5-TRIMETHYL-3-THIOMORPHOLINECARBOXYLIC ACID, 1-OXIDE

Common Name

English

Classification Tree Code System Code

NCI_THESAURUS

C263