U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

Approval Year

Unknown
149124
Substance Class Protein
Created
by admin
on Tue Apr 01 23:18:20 GMT 2025
Edited
by admin
on Tue Apr 01 23:18:20 GMT 2025
Protein Type FC FUSION PROTEIN
Protein Sub Type INTERLEUKINS
Sequence Origin HUMAN
Sequence Type COMPLETE
Record UNII
NYZ11835VX
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
INTERLEUKIN 22 (HUMAN (MATURE)) FUSION PROTEIN WITH IMMUNOGLOBULIN G4 (SYNTHETIC HUMAN .GAMMA.4-CHAIN FC REGION (81-GLYCINE)), DIMER
Preferred Name English
EFMARODOCOKIN ALFA
USAN   INN  
Official Name English
IL 22-FC
Common Name English
RG-7880
Code English
RG7880
Code English
EFMARODOCOKIN ALFA [USAN]
Common Name English
efmarodocokin alfa [INN]
Common Name English
RO-7021610
Code English
HUMAN INTERLEUKIN 22 (1-146), FUSED TO HUMAN IMMUNOGLOBULIN HEAVY CONSTANT GAMMA 4 (CH1(97-98), H(S10>P(158)), CH2(N67>G(227)))-(147-377), DIMER (156-156':159-159')-BISDISULFIDE, PRODUCED IN CHO CELLS, GLYCOFORM ALFA
Common Name English
RO7021610
Code English
Efmarodocokin alfa [WHO-DD]
Common Name English
Code System Code Type Description
USAN
HI-205
Created by admin on Tue Apr 01 23:18:20 GMT 2025 , Edited by admin on Tue Apr 01 23:18:20 GMT 2025
PRIMARY
CAS
1953227-87-6
Created by admin on Tue Apr 01 23:18:20 GMT 2025 , Edited by admin on Tue Apr 01 23:18:20 GMT 2025
NO STRUCTURE GIVEN
FDA UNII
NYZ11835VX
Created by admin on Tue Apr 01 23:18:20 GMT 2025 , Edited by admin on Tue Apr 01 23:18:20 GMT 2025
PRIMARY
INN
11266
Created by admin on Tue Apr 01 23:18:20 GMT 2025 , Edited by admin on Tue Apr 01 23:18:20 GMT 2025
PRIMARY
NCI_THESAURUS
C174771
Created by admin on Tue Apr 01 23:18:20 GMT 2025 , Edited by admin on Tue Apr 01 23:18:20 GMT 2025
PRIMARY
SMS_ID
300000023639
Created by admin on Tue Apr 01 23:18:20 GMT 2025 , Edited by admin on Tue Apr 01 23:18:20 GMT 2025
PRIMARY
CAS
2247840-74-8
Created by admin on Tue Apr 01 23:18:20 GMT 2025 , Edited by admin on Tue Apr 01 23:18:20 GMT 2025
PRIMARY
From To
1_7 1_99
1_56 1_145
1_156 2_156
1_159 2_159
1_191 1_251
1_297 1_355
2_7 2_99
2_56 2_145
2_191 2_251
2_297 2_355
Glycosylation Type MAMMALIAN
Glycosylation Link Type Site
N 1_21
N 1_35
N 1_64
N 2_21
N 2_35
N 2_64
Related Record Type Details
IL-22 RECEPTOR
TARGET->LIGAND
Related Record Type Details
EFMARODOCOKIN ALFA
ACTIVE MOIETY
Name Property Type Amount Referenced Substance Defining Parameters References
MOL_WEIGHT:NUMBER(CALCULATED) CHEMICAL
Molecular Formula CHEMICAL
NIH
NCATS
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