Details
| Stereochemistry | ACHIRAL |
| Molecular Formula | C12H4Br6O |
| Molecular Weight | 643.584 |
| Optical Activity | NONE |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
BrC1=CC(Br)=C(OC2=CC(Br)=C(Br)C=C2Br)C=C1Br
InChI
InChIKey=RZXIRSKYBISPGF-UHFFFAOYSA-N
InChI=1S/C12H4Br6O/c13-5-1-9(17)11(3-7(5)15)19-12-4-8(16)6(14)2-10(12)18/h1-4H
| Molecular Formula | C12H4Br6O |
| Molecular Weight | 643.584 |
| Charge | 0 |
| Count |
|
| Stereochemistry | ACHIRAL |
| Additional Stereochemistry | No |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Optical Activity | NONE |
Approval Year
PubMed
| Title | Date | PubMed |
|---|---|---|
| Environmental contaminants activate human and polar bear (Ursus maritimus) pregnane X receptors (PXR, NR1I2) differently. | 2015-04-01 |
|
| Organic anion transporting polypeptides in the hepatic uptake of PBDE congeners in mice. | 2011-11-15 |
|
| Hepatic in vitro toxicity assessment of PBDE congeners BDE47, BDE153 and BDE154 in Atlantic salmon (Salmo salar L.). | 2011-10 |
|
| Polybrominated diphenyl ethers and arylhydrocarbon receptor agonists: Different toxicity and target gene expression. | 2010-10-05 |
|
| Computational studies of interactions between endocrine disrupting chemicals and androgen receptor of different vertebrate species. | 2010-07 |
|
| Mechanism of polybrominated diphenyl ether uptake into the liver: PBDE congeners are substrates of human hepatic OATP transporters. | 2010-06 |
|
| Changes in mitogen-activated protein kinase in cerebellar granule neurons by polybrominated diphenyl ethers and polychlorinated biphenyls. | 2010-05-15 |
|
| Nuclear hormone receptor activity of polybrominated diphenyl ethers and their hydroxylated and methoxylated metabolites in transactivation assays using Chinese hamster ovary cells. | 2009-08 |
|
| Polybrominated diphenyl ethers in human serum and sperm quality. | 2008-04 |
|
| Measurement of polybrominated diphenyl ethers and metabolites in mouse plasma after exposure to a commercial pentabromodiphenyl ether mixture. | 2007-07 |
|
| Physicochemical properties of selected polybrominated diphenyl ethers and extension of the UNIFAC model to brominated aromatic compounds. | 2007-04 |
|
| Bioaccumulation and biotransformation of 61 polychlorinated biphenyl and four polybrominated diphenyl ether congeners in juvenile American kestrels (Falco sparverius). | 2007-02 |
|
| Disposition of 2,2',4,4',5,5'-hexabromodiphenyl ether (BDE153) and its interaction with other polybrominated diphenyl ethers (PBDEs) in rodents. | 2006-09 |
|
| Interactions of polybrominated diphenyl ethers with the aryl hydrocarbon receptor pathway. | 2006-07 |
|
| In vitro profiling of the endocrine-disrupting potency of brominated flame retardants. | 2006-07 |
|
| Photochemistry of a major commercial polybrominated diphenyl ether flame retardant congener: 2,2',4,4',5,5'-hexabromodiphenyl ether (BDE153). | 2006-07 |
|
| Concentrations of polybrominated diphenyl ethers, polychlonnated biphenyls, and polychlorobiphenylols in serum from pregnant Faroese women and their children 7 years later. | 2005-12-15 |
|
| Differential expression of CYP1A, 2B, and 3A genes in the F344 rat following exposure to a polybrominated diphenyl ether mixture or individual components. | 2005-11 |
|
| Brominated-chlorinated diphenyl ethers formed by thermolysis of polybrominated diphenyl ethers at low temperatures. | 2005-09 |
|
| Effects of polybrominated diphenyl ethers on basal and TCDD-induced ethoxyresorufin activity and cytochrome P450-1A1 expression in MCF-7, HepG2, and H4IIE cells. | 2004-12 |
|
| Brominated flame retardants and phenolic endocrine disrupters in Finnish human adipose tissue. | 2003-12 |
|
| Neonatal exposure to polybrominated diphenyl ether (PBDE 153) disrupts spontaneous behaviour, impairs learning and memory, and decreases hippocampal cholinergic receptors in adult mice. | 2003-10-15 |
|
| Polybrominated dibenzo-p-dioxins, dibenzofurans, and diphenyl ethers in Japanese human adipose tissue. | 2003-03-01 |
|
| Brominated flame retardants in archived serum samples from Norway: a study on temporal trends and the role of age. | 2002-04-01 |
|
| Brominated flame retardants in serum from U.S. blood donors. | 2001-10-01 |
|
| Brominated flame retardants in plasma samples from three different occupational groups in Norway. | 2001-08 |
Patents
| Substance Class |
Chemical
Created
by
admin
on
Edited
Mon Mar 31 21:57:27 GMT 2025
by
admin
on
Mon Mar 31 21:57:27 GMT 2025
|
| Record UNII |
NX58WCQ511
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| Record Status |
Validated (UNII)
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| Record Version |
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DTXSID4030047
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NX58WCQ511
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155166
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C184300
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68631-49-2
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