TYROSINE-PROTEIN KINASE ITK/TSK

Approval Year

Substance Class	Protein
Protein Sub Type
Sequence Type	COMPLETE
Record UNII	NVK8I2L7PB
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

IL-2-INDUCIBLE T-CELL KINASE

Preferred Name

English

TYROSINE-PROTEIN KINASE ITK/TSK

Common Name

English

INTERLEUKIN-2-INDUCIBLE T-CELL KINASE

Common Name

English

TYROSINE-PROTEIN KINASE LYK

Common Name

English

LYK

Common Name

English

Showing 1 to 5 of 7 entries

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Code System

Code

Type

Description

FDA UNII

NVK8I2L7PB

PRIMARY

PHAROS

Q08881

PRIMARY

UNIPROT

Q08881

PRIMARY

Showing 1 to 3 of 3 entries

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Subunit 0

Linkage Type	Residue Index
ZINC FINGER	1_113	1_149

Related Record Type Details


					P0BJU71YZI

N-(2-(6,6-dimethyl-4,5,6,7-tetrahydro-1H-indazol-3-yl)-1H-indol-6-yl)-N-methyl-2-morpholinopropanamide, (S)-

INHIBITOR -> TARGET

Amount:


					1X70OSD4VX

IBRUTINIB

INHIBITOR->OFF-TARGET

Amount:

77.9 (average)

Structural Modifications

Modification Type	Location Site	Location Type	Residue Modified	Extent	Fragment Name	Fragment Approval
AMINO ACID SUBSTITUTION	[1_565]				DEXFOSFOSERINE	VI4F0K069V

Name	Property Type	Amount	Referenced Substance	Defining	Parameters	References
MOL_WEIGHT	CHEMICAL