Inpegsomatropin

U.S. Department of Health & Human Services Divider Arrow

National Institutes of Health Divider Arrow

NCATS

Approval Year

Substance Class	Protein Created by `admin` on `Wed Apr 02 16:52:30 GMT 2025` Edited by `admin` on `Wed Apr 02 16:52:30 GMT 2025`
Protein Sub Type
Record UNII	NUB86ZJ8XT
Record Status	`Validated (UNII)`
Record Version

Download

Name

Type

Language

Inpegsomatropin

Official Name

English

Recombinant human somatotropin (growth hormone, GH), conjugated to a multi-arm polyethylene glycol carrier molecule (somatotropin (human), produced by Pichia pastoris, non-glycosylated, N-terminal or N6.Lys mono-substituted with one (2-[?-methoxypoly(oxy

Preferred Name

English

inpegsomatropin [INN]

Common Name

English

Somatotropin (recombinant human), 1(38,70,140,145 or 158)-amide with ?-hydro-?-methoxypoly(oxy-1,2-ethanediyl) ether with N-(2-hydroxyacetyl)-N-(2-hydroxyethyl)glycine (2:1)

Common Name

English

Code System Code Type Description

CAS

2656386-75-1

Created by admin on Wed Apr 02 16:52:30 GMT 2025 , Edited by admin on Wed Apr 02 16:52:30 GMT 2025

PRIMARY

SMS_ID

300000053747

Created by admin on Wed Apr 02 16:52:30 GMT 2025 , Edited by admin on Wed Apr 02 16:52:30 GMT 2025

PRIMARY

INN

12422

Created by admin on Wed Apr 02 16:52:30 GMT 2025 , Edited by admin on Wed Apr 02 16:52:30 GMT 2025

PRIMARY

NCI_THESAURUS

C199062

Created by admin on Wed Apr 02 16:52:30 GMT 2025 , Edited by admin on Wed Apr 02 16:52:30 GMT 2025

PRIMARY

FDA UNII

NUB86ZJ8XT

Created by admin on Wed Apr 02 16:52:30 GMT 2025 , Edited by admin on Wed Apr 02 16:52:30 GMT 2025

PRIMARY

Related Record Type Details


					NQX9KB6PCL

TARGET->MIMETIC

Amount:

Related Record Type Details


					NUB86ZJ8XT

Inpegsomatropin

ACTIVE MOIETY

Amount:

Structural Modifications

Modification Type	Location Site	Location Type	Residue Modified	Extent	Fragment Name	Fragment Approval
AMINO_ACID_SUBSTITUTION	[1_38] [1_70] [1_140] [1_145] [1_158]			Amount:	Inpegsomatropin-lysine PEG (40000 MW)	8L5XUJ2R34
AMINO_ACID_SUBSTITUTION	[1_1]	N-TERMINUS		Amount:	Inpegsomatropin-phenylalanine PEG (40000 MW)	93UC5FX8NU

Name	Property Type	Amount	Referenced Substance	Defining	Parameters	References
Molecular Formula	CHEMICAL
MOL_WEIGHT:NUMBER(CALCULATED)	CHEMICAL