BAZINAPRINE

Possibly Marketed Outside US

Details

Stereochemistry	ACHIRAL
Molecular Formula	C17H19N5O
Molecular Weight	309.3657
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

N#CC1=CC(=NN=C1NCCN2CCOCC2)C3=CC=CC=C3

InChI

InChIKey=KRNDIPHOJLIHRI-UHFFFAOYSA-N

InChI=1S/C17H19N5O/c18-13-15-12-16(14-4-2-1-3-5-14)20-21-17(15)19-6-7-22-8-10-23-11-9-22/h1-5,12H,6-11H2,(H,19,21)

HIDE SMILES / InChI

Molecular Formula	C17H19N5O
Molecular Weight	309.3657
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Description
Sources: https://adisinsight.springer.com/drugs/800000672 | https://www.ncbi.nlm.nih.gov/pubmed/3100771

Bazinaprine (also known as SR 95191) is a novel psychotropic drug, which possesses the pharmacological properties of a selective, reversible type A monoamine oxidase inhibitor (MAO). It was studied for the treatment of depression, but that use was discontinued.

Originator

Approval Year

PubMed

Title	Date	PubMed
Alterations of serotonin neurotransmission and inhibition of mouse-killing behavior: III. Effects of minaprine, CM 30366 and SR 95191.	1989-07	2531423
Monoamine oxidase-inhibiting properties of SR 95191, a new pyridazine derivative, in the rat: evidence for selective and reversible inhibition of monoamine oxidase type A in vivo but not in vitro.	1988-04	3346672
SR 95191, a selective inhibitor of type A monoamine oxidase with dopaminergic properties. I. Psychopharmacological profile in rodents.	1987-01	3100770

Substance Class	Chemical Created by `admin` on `Mon Mar 31 18:16:21 GMT 2025` Edited by `admin` on `Mon Mar 31 18:16:21 GMT 2025`
Record UNII	NU8Y4C529J
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

BAZINAPRINE

Official Name

English

bazinaprine [INN]

Preferred Name

English

3-((2-MORPHOLINOETHYL)AMINO)-6-PHENYL-4-PYRIDAZINECARBONITRILE

Systematic Name

English

Classification Tree Code System Code

NCI_THESAURUS

C265