BAZINAPRINE

Possibly Marketed Outside US

Details

Stereochemistry	ACHIRAL
Molecular Formula	C17H19N5O
Molecular Weight	309.3657
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

N#CC1=CC(=NN=C1NCCN2CCOCC2)C3=CC=CC=C3

InChI

InChIKey=KRNDIPHOJLIHRI-UHFFFAOYSA-N

InChI=1S/C17H19N5O/c18-13-15-12-16(14-4-2-1-3-5-14)20-21-17(15)19-6-7-22-8-10-23-11-9-22/h1-5,12H,6-11H2,(H,19,21)

HIDE SMILES / InChI

Molecular Formula	C17H19N5O
Molecular Weight	309.3657
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Description
Sources: https://adisinsight.springer.com/drugs/800000672 | https://www.ncbi.nlm.nih.gov/pubmed/3100771

Bazinaprine (also known as SR 95191) is a novel psychotropic drug, which possesses the pharmacological properties of a selective, reversible type A monoamine oxidase inhibitor (MAO). It was studied for the treatment of depression, but that use was discontinued.

Originator

Approval Year

PubMed

Title	Date	PubMed
SR 95191, a selective inhibitor of type A monoamine oxidase with dopaminergic properties. I. Psychopharmacological profile in rodents.	1987 Jan	3100770
Monoamine oxidase-inhibiting properties of SR 95191, a new pyridazine derivative, in the rat: evidence for selective and reversible inhibition of monoamine oxidase type A in vivo but not in vitro.	1988 Apr	3346672
Alterations of serotonin neurotransmission and inhibition of mouse-killing behavior: III. Effects of minaprine, CM 30366 and SR 95191.	1989 Jul	2531423

Substance Class	Chemical Created by `admin` on `Fri Dec 15 16:00:59 UTC 2023` Edited by `admin` on `Fri Dec 15 16:00:59 UTC 2023`
Record UNII	NU8Y4C529J
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

BAZINAPRINE

Official Name

English

bazinaprine [INN]

Common Name

English

3-((2-MORPHOLINOETHYL)AMINO)-6-PHENYL-4-PYRIDAZINECARBONITRILE

Systematic Name

English

Classification Tree Code System Code

NCI_THESAURUS

C265