U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

Approval Year

Substance Class Protein
Created
by admin
on Sat Dec 16 14:33:36 GMT 2023
Edited
by admin
on Sat Dec 16 14:33:36 GMT 2023
Protein Type MONOCLONAL ANTIBODY
Protein Sub Type IGG1
Sequence Origin HUMAN
Sequence Type COMPLETE
Record UNII
NR4MAD6PPB
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
LODAPOLIMAB
INN   USAN  
Official Name English
Lodapolimab [WHO-DD]
Common Name English
LODAPOLIMAB [USAN]
Common Name English
IMMUNOGLOBULIN G1-LAMBDA, ANTI-(HOMO SAPIENS PROGRAMMED CELL DEATH 1 LIGAND 1 (PROGRAMMED DEATH LIGAND 1, B7 HOMOLOG 1, PD-L1, CD274 ANTIGEN)) HUMAN MONOCLONAL ANTIBODY .GAMMA.1 HEAVY CHAIN (1-453) (HOMO SAPIENS VH (IGHV1-69*06(IGHD)-IGHJ6*01 (8.8.16) (1
Systematic Name English
lodapolimab [INN]
Common Name English
LY-3300054
Code English
IMMUNOGLOBULIN G1 (240-ALANINE, 241-GLUTAMIC ACID, 243-ALANINE, 336-SERINE, 337-SERINE), ANTI-(HUMAN PROGRAMMED DEATH-LIGAND 1) (HUMAN MONOCLONAL LY3300054 .GAMMA.1-CHAIN), DISULFIDE WITH HUMAN MONOCLONAL LY3300054 .LAMBDA.-CHAIN, DIMER
Systematic Name English
LY3300054, A FULLY HUMAN IGG1.LAMBDA. ANTI-PD-L1 MONOCLONAL ANTIBODY
Common Name English
LY3300054
Code English
Code System Code Type Description
USAN
FG-118
Created by admin on Sat Dec 16 14:33:37 GMT 2023 , Edited by admin on Sat Dec 16 14:33:37 GMT 2023
PRIMARY
INN
11185
Created by admin on Sat Dec 16 14:33:37 GMT 2023 , Edited by admin on Sat Dec 16 14:33:37 GMT 2023
PRIMARY
NCI_THESAURUS
C128138
Created by admin on Sat Dec 16 14:33:37 GMT 2023 , Edited by admin on Sat Dec 16 14:33:37 GMT 2023
PRIMARY
FDA UNII
NR4MAD6PPB
Created by admin on Sat Dec 16 14:33:37 GMT 2023 , Edited by admin on Sat Dec 16 14:33:37 GMT 2023
PRIMARY
CAS
2118349-31-6
Created by admin on Sat Dec 16 14:33:37 GMT 2023 , Edited by admin on Sat Dec 16 14:33:37 GMT 2023
PRIMARY
From To
1_22 1_96
2_22 2_96
2_150 2_206
2_226 4_215
2_267 2_327
1_150 1_206
2_373 2_431
3_22 3_89
3_138 3_197
4_22 4_89
4_138 4_197
1_226 3_215
1_232 2_232
1_235 2_235
1_267 1_327
1_373 1_431
Glycosylation Type MAMMALIAN
Glycosylation Link Type Site
N 1_303
N 2_303
Related Record Type Details
TARGET -> INHIBITOR
Related Record Type Details
ACTIVE MOIETY
Name Property Type Amount Referenced Substance Defining Parameters References
Molecular Formula CHEMICAL
MOL_WEIGHT:NUMBER(CALCULATED) CHEMICAL