Details
| Stereochemistry | RACEMIC |
| Molecular Formula | C18H34O3 |
| Molecular Weight | 298.4608 |
| Optical Activity | ( + / - ) |
| Defined Stereocenters | 0 / 1 |
| E/Z Centers | 0 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
CCCCCCCCCCCCCCC1(CO1)C(=O)OC
InChI
InChIKey=RSSDZUNGAWCFPT-UHFFFAOYSA-N
InChI=1S/C18H34O3/c1-3-4-5-6-7-8-9-10-11-12-13-14-15-18(16-21-18)17(19)20-2/h3-16H2,1-2H3
| Molecular Formula | C18H34O3 |
| Molecular Weight | 298.4608 |
| Charge | 0 |
| Count |
|
| Stereochemistry | RACEMIC |
| Additional Stereochemistry | No |
| Defined Stereocenters | 0 / 1 |
| E/Z Centers | 0 |
| Optical Activity | ( + / - ) |
Methyl palmoxirate, an oral hypoglycemic agent, was studied as a selective and irreversible inhibitor of the mitochondrial enzyme carnitine palmitoyltransferase and of long-chain fatty acid oxidation to treat diabetes. In addition, this compound was used to study the brain lipid metabolism by quantitative autoradiography or positron emission tomography (PET).
Approval Year
PubMed
| Title | Date | PubMed |
|---|---|---|
| Impact of in vivo fatty acid oxidation blockade on glucose turnover and muscle glucose metabolism during low-dose AICAR infusion. | 2006-11 |
|
| A potential role for triglyceride as an energy source during bovine oocyte maturation and early embryo development. | 2006-09 |
|
| Oleate-induced decrease in hepatocyte insulin binding is mediated by PKC-delta. | 2006-08-04 |
|
| Metabolic fuels, neuropeptide Y, and estrous behavior in Syrian hamsters. | 2004-05-08 |
|
| Etomoxir, a fatty acid oxidation inhibitor, increases food intake and reduces hepatic energy status in rats. | 2004-03 |
|
| Do metabolic signals stimulate intake in rat pups? | 2003-06 |
|
| Beta -oxidation of free fatty acids is required to maintain translational control of protein synthesis in heart. | 2002-12 |
|
| Role of vagal afferent innervation in feeding and brain Fos expression produced by metabolic inhibitors. | 2001-11-23 |
|
| Metabolic and behavioral responses in pre-weanling rats following alteration of maternal diet. | 2001-01 |
Patents
| Substance Class |
Chemical
Created
by
admin
on
Edited
Mon Mar 31 19:10:28 GMT 2025
by
admin
on
Mon Mar 31 19:10:28 GMT 2025
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| Record UNII |
NPL6006Y4B
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| Record Status |
Validated (UNII)
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| Record Version |
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NPL6006Y4B
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C174760
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300000055279
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CHEMBL12261
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68593
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69207-52-9
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359682
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