METHYL PALMOXIRATE

Details

Stereochemistry	RACEMIC
Molecular Formula	C18H34O3
Molecular Weight	298.4608
Optical Activity	( + / - )
Defined Stereocenters	0 / 1
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

CCCCCCCCCCCCCCC1(CO1)C(=O)OC

InChI

InChIKey=RSSDZUNGAWCFPT-UHFFFAOYSA-N

InChI=1S/C18H34O3/c1-3-4-5-6-7-8-9-10-11-12-13-14-15-18(16-21-18)17(19)20-2/h3-16H2,1-2H3

HIDE SMILES / InChI

Molecular Formula	C18H34O3
Molecular Weight	298.4608
Charge	0
Count

Stereochemistry	RACEMIC
Additional Stereochemistry	No
Defined Stereocenters	0 / 1
E/Z Centers	0
Optical Activity	( + / - )

Description
Sources: https://www.ncbi.nlm.nih.gov/pubmed/9820128 | https://www.ncbi.nlm.nih.gov/pubmed/3401631

Methyl palmoxirate, an oral hypoglycemic agent, was studied as a selective and irreversible inhibitor of the mitochondrial enzyme carnitine palmitoyltransferase and of long-chain fatty acid oxidation to treat diabetes. In addition, this compound was used to study the brain lipid metabolism by quantitative autoradiography or positron emission tomography (PET).

Approval Year

PubMed

Title	Date	PubMed
Do metabolic signals stimulate intake in rat pups?	2003 Jun	12818711
Etomoxir, a fatty acid oxidation inhibitor, increases food intake and reduces hepatic energy status in rats.	2004 Mar	15059695

Patents

Sample Use Guides

In Vivo Use Guide

2.5 and 10 mg/kg

Route of Administration: Oral

Substance Class	Chemical Created by `admin` on `Fri Dec 15 18:19:54 GMT 2023` Edited by `admin` on `Fri Dec 15 18:19:54 GMT 2023`
Record UNII	NPL6006Y4B
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

METHYL PALMOXIRATE

Official Name

English

OXIRANECARBOXYLIC ACID, 2-TETRADECYL-, METHYL ESTER, (±)-

Common Name

English

METHYL PALMOXIRATE [USAN]

Common Name

English

NSC-359682

Code

English

MCN-3716

Code

English

Code System Code Type Description

FDA UNII

NPL6006Y4B