Details
| Stereochemistry | ACHIRAL |
| Molecular Formula | C8H8O4 |
| Molecular Weight | 168.1467 |
| Optical Activity | NONE |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
OC(=O)CC1=CC(O)=CC=C1O
InChI
InChIKey=IGMNYECMUMZDDF-UHFFFAOYSA-N
InChI=1S/C8H8O4/c9-6-1-2-7(10)5(3-6)4-8(11)12/h1-3,9-10H,4H2,(H,11,12)
| Molecular Formula | C8H8O4 |
| Molecular Weight | 168.1467 |
| Charge | 0 |
| Count |
|
| Stereochemistry | ACHIRAL |
| Additional Stereochemistry | No |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Optical Activity | NONE |
Approval Year
PubMed
| Title | Date | PubMed |
|---|---|---|
| Identification and characterization of an Arabidopsis homogentisate phytyltransferase paralog. | 2006-05 |
|
| Ochronotic rheumatism in Algeria: clinical, radiological, biological and molecular studies--a case study of 14 patients in 11 families. | 2006-05 |
|
| Analysis of aromatic catabolic pathways in Pseudomonas putida KT 2440 using a combined proteomic approach: 2-DE/MS and cleavable isotope-coded affinity tag analysis. | 2006-02 |
|
| Arthroscopic treatment of shoulder ochronotic arthropathy: a case report and review of literature. | 2006-02 |
|
| Early detection of alkaptonuria. | 2006-01-06 |
|
| In vivo genetic selection of renal proximal tubules. | 2006-01 |
|
| Catalytic reaction mechanism of homogentisate dioxygenase: a hybrid DFT study. | 2005-12-14 |
|
| Spectroscopic and computational studies of NTBC bound to the non-heme iron enzyme (4-hydroxyphenyl)pyruvate dioxygenase: active site contributions to drug inhibition. | 2005-12-09 |
|
| Ochronotic arthropathy: disappearance of alkaptonuria after liver transplantation for hepatitis B-related cirrhosis. | 2005-12 |
|
| Hip arthroplasty for ochronosis. | 2005-11 |
|
| Alkaptonuria diagnosed by flexible bronchoscopy. | 2005-11 |
|
| Direct chromatographic methods for the rapid determination of homogentisic acid in strawberry tree (Arbutus unedo L.) honey. | 2005-10-07 |
|
| [Endogenous ochronosis: a case description]. | 2005-10 |
|
| Radiographic and MRI findings in ochronosis. | 2005-10 |
|
| Metabolic regulation at the tricarboxylic acid and glyoxylate cycles of the lignin-degrading basidiomycete Phanerochaete chrysosporium against exogenous addition of vanillin. | 2005-10 |
|
| Benzene rings. | 2005-08-16 |
|
| A genetically engineered strain of Pseudomonas putida as a useful tool for identifying new therapeutic herbicides. | 2005-08-15 |
|
| Identification of a homogentisate-1,2-dioxygenase gene in the fungus Exophiala lecanii-corni: analysis and implications. | 2005-08 |
|
| Ochronotic arthritis: case reports and review of the literature. | 2005-08 |
|
| [Subarachnoid anesthesia in a patient with alkaptonuric ochronosis]. | 2005-07-26 |
|
| A two-component hydroxylase involved in the assimilation of 3-hydroxyphenyl acetate in Pseudomonas putida. | 2005-07-15 |
|
| Characterization of transplastomic tobacco plants with a plastid localized barley 4-hydroxyphenylpyruvate dioxygenase. | 2005-07 |
|
| Determination of peroxidase encapsulated in liposomes using homogentisic acid y-lactone chemiluminescence. | 2005-06 |
|
| Use of nitisinone in patients with alkaptonuria. | 2005-06 |
|
| Accumulation of multiple intermediates in the catalytic cycle of (4-hydroxyphenyl)pyruvate dioxygenase from Streptomyces avermitilis. | 2005-05-17 |
|
| The TyrA family of aromatic-pathway dehydrogenases in phylogenetic context. | 2005-05-12 |
|
| Cutaneous markers in ochronosis. | 2005-05 |
|
| Alkaptonuria and photography: a patient's urine tells the story. | 2005-04-12 |
|
| Steady-state kinetics and inhibition of anaerobically purified human homogentisate 1,2-dioxygenase. | 2005-03-01 |
|
| p-Hydroxyphenylpyruvate dioxygenase inhibitor-resistant plants. | 2005-03 |
|
| Alkaptonuric ochronosis: a case report. | 2005-02 |
|
| 4-Hydroxyphenylpyruvate dioxygenase. | 2005-01-01 |
|
| On-line counting of cysteine residues in peptides during electrospray ionization by electrogenerated tags and their application to protein identification. | 2005-01 |
|
| [Important bilateral corneal astigmatism in a case of ocular ochronosis]. | 2005 |
|
| Alkaptonuric ochronosis with aortic valve and joint replacements and femoral fracture: a case report and literature review. | 2004-11 |
|
| Minocycline-induced hyperpigmentation masquerading as alkaptonuria in individuals with joint pain. | 2004-11 |
|
| Alkaptonuria and renal failure: a case report. | 2004-09-15 |
|
| Renal proximal tubular cells acquire resistance to cell death stimuli in mice with hereditary tyrosinemia type 1. | 2004-09 |
|
| Enhancement of vitamin E production in sunflower cell cultures. | 2004-09 |
|
| A rational treatment of Mendelian genetics. | 2004-08-31 |
|
| Pigmented conjunctival lesions as initial manifestation of ochronosis. | 2004-07 |
|
| Bilateral achilles tendon ruptures in a patient with ochronosis: a case report. | 2004-07 |
|
| Antiplasmodial agents from the leaves of Glossocalyx brevipes. | 2004-05 |
|
| The crystal structures of Zea mays and Arabidopsis 4-hydroxyphenylpyruvate dioxygenase. | 2004-04 |
|
| Homogentisic acid derivatives from Miliusa balansae. | 2004-03 |
|
| Alkaptonuria, ochronosis, and ochronotic arthropathy. | 2004-02 |
|
| Chronic liver disease in murine hereditary tyrosinemia type 1 induces resistance to cell death. | 2004-02 |
|
| [Perioperative management of a patient with alcaptonuria--a case report]. | 2004 |
|
| [Case report of a patient with ochronosis and arthroplasty of the hip and both knees]. | 2003 |
|
| Alkaptonuria and renal failure: a case report and review of the literature. | 1992-07 |
Patents
| Substance Class |
Chemical
Created
by
admin
on
Edited
Mon Mar 31 19:56:39 GMT 2025
by
admin
on
Mon Mar 31 19:56:39 GMT 2025
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| Record UNII |
NP8UE6VF08
|
| Record Status |
Validated (UNII)
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| Record Version |
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Preferred Name | English | ||
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| Code System | Code | Type | Description | ||
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DB08327
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451-13-8
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44747
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NP8UE6VF08
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88940
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DTXSID1060005
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m6045
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PRIMARY | Merck Index | ||
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780
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HOMOGENTISIC ACID
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207-192-7
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