ISOGANCICLOVIR

Details

Stereochemistry	RACEMIC
Molecular Formula	C9H13N5O4
Molecular Weight	255.2306
Optical Activity	( + / - )
Defined Stereocenters	0 / 1
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

NC1=NC2=C(N=CN2COCC(O)CO)C(=O)N1

InChI

InChIKey=YMJRISBBXAOKCD-UHFFFAOYSA-N

InChI=1S/C9H13N5O4/c10-9-12-7-6(8(17)13-9)11-3-14(7)4-18-2-5(16)1-15/h3,5,15-16H,1-2,4H2,(H3,10,12,13,17)

HIDE SMILES / InChI

Molecular Formula	C9H13N5O4
Molecular Weight	255.2306
Charge	0
Count

Stereochemistry	RACEMIC
Additional Stereochemistry	No
Defined Stereocenters	0 / 1
E/Z Centers	0
Optical Activity	( + / - )

Approval Year

PubMed

Title	Date	PubMed
Synthesis and antiherpetic activity of (S)-, (R)-, and (+/-)-9-[(2,3-dihydroxy-1-propoxy)methyl]guanine, linear isomers of 2'-nor-2'-deoxyguanosine.	1985 Jul	2989523
Successful treatment of murine cytomegalovirus disease does not prevent latent virus infection.	1986 Aug	3016127
Treatment of serious cytomegalovirus infections with 9-(1,3-dihydroxy-2-propoxymethyl)guanine in patients with AIDS and other immunodeficiencies.	1986 Mar 27	3005861
Synthesis and antiherpes virus activity of phosphate and phosphonate derivatives of 9-[(1,3-dihydroxy-2-propoxy)methyl]guanine.	1986 May	3009811
Fine structure of cells infected with human cytomegalovirus after treatment with 9-(1,3-dihydroxy-2-propoxymethyl)guanine.	1987 Jun	3035059
Responses of neurologic complications of AIDS to 3'-azido-3'-deoxythymidine and 9-(1,3-dihydroxy-2-propoxymethyl) guanine. I. Clinical features.	1988 Mar-Apr	3163817

Patents

Substance Class	Chemical Created by `admin` on `Sat Dec 16 04:40:39 UTC 2023` Edited by `admin` on `Sat Dec 16 04:40:39 UTC 2023`
Record UNII	NNJ00018WY
Record Status	`Validated (UNII)`
Record Version

Download

Name

Type

Language

ISOGANCICLOVIR

Common Name

English

(±)-2-AMINO-9-((2,3-DIHYDROXYPROPOXY)METHYL)-1,9-DIHYDRO-6H-PURIN-6-ONE

Systematic Name

English

GANCICLOVIR IMPURITY E [EP IMPURITY]

Common Name

English

GANCICLOVIR RELATED COMPOUND A [USP-RS]

Common Name

English

6H-PURIN-6-ONE, 2-AMINO-9-((2,3-DIHYDROXYPROPOXY)METHYL)-1,9-DIHYDRO-

Systematic Name

English

GANCICLOVIR RELATED COMPOUND A

Common Name

English

(RS)-2-AMINO-9-(2,3-DIHYDROXY-PROPOXYMETHYL)-1,9-DIHYDRO-PURIN-6-ONE

Systematic Name

English

2-AMINO-9-((2,3-DIHYDROXYPROPOXY)METHYL)-1,9-DIHYDRO-6H-PURIN-6-ONE

Systematic Name

English

GANCICLOVIR RELATED COMPOUND A [USP IMPURITY]

Common Name

English

2-AMINO-9-(((2RS)-2,3-DIHYDROXYPROPOXY)METHYL)-1,9-DIHYDRO-6H-PURIN-6-ONE

Systematic Name

English

3-((2-AMINO-6-HYDROXY-9H-PURIN-9-YL)METHOXY)-1,2-PROPANEDIOL

Systematic Name

English

Code System Code Type Description

RS_ITEM_NUM

1288317

Created by admin on Sat Dec 16 04:40:39 UTC 2023 , Edited by admin on Sat Dec 16 04:40:39 UTC 2023

PRIMARY

FDA UNII

NNJ00018WY

Created by admin on Sat Dec 16 04:40:39 UTC 2023 , Edited by admin on Sat Dec 16 04:40:39 UTC 2023

PRIMARY

CAS

86357-09-7

Created by admin on Sat Dec 16 04:40:39 UTC 2023 , Edited by admin on Sat Dec 16 04:40:39 UTC 2023

PRIMARY

PUBCHEM

135446919

Created by admin on Sat Dec 16 04:40:39 UTC 2023 , Edited by admin on Sat Dec 16 04:40:39 UTC 2023

PRIMARY

Related Record Type Details


					P9G3CKZ4P5

GANCICLOVIR

PARENT -> IMPURITY

Interaction Type:

CHROMATOGRAPHIC PURITY (HPLC/UV)

Qualification:

USP

Amount: