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Details

Stereochemistry ACHIRAL
Molecular Formula C18H40N4O4.2Br
Molecular Weight 536.343
Optical Activity NONE
Defined Stereocenters 0 / 2
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of HEXCARBACHOLINE BROMIDE

SMILES

[Br-].[Br-].C[N+](C)(C)CCOC(=O)NCCCCCCNC(=O)OCC[N+](C)(C)C

InChI

InChIKey=AFWBFAMUEOVLFX-UHFFFAOYSA-N
InChI=1S/C18H38N4O4.2BrH/c1-21(2,3)13-15-25-17(23)19-11-9-7-8-10-12-20-18(24)26-16-14-22(4,5)6;;/h7-16H2,1-6H3;2*1H

HIDE SMILES / InChI

Molecular Formula BrH
Molecular Weight 80.912
Charge 0
Count
MOL RATIO 2 MOL RATIO (average)
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Molecular Formula C18H40N4O4
Molecular Weight 376.5346
Charge 2
Count
MOL RATIO 1 MOL RATIO (average)
Stereochemistry MIXED
Additional Stereochemistry No
Defined Stereocenters 0 / 2
E/Z Centers 0
Optical Activity NONE

Description

Hexacarbacholine is a long-acting muscle-relaxant drug that had been used extensively in Europe in surgical anesthesia, but had had considerably less clinical usage in US. There is no precise agreement concerning the mode of action of hexacarbacholine at the myoneural junction. Therapeutic doses of the drug do not appear to influence the cardiovascular system, cardiac activity, or blood pressure, although large doses do cause slight and transient increases in blood pressure in laboratory animals. The intraocular tension in man is increased temporarily following the administration of hexacarbacholine. Since hexacarbacholine is a cumulative drug, repeated administrations should be avoided. It may cause cardiac arrest due to a hyperkalaemia.

Approval Year

Sample Use Guides

In Vivo Use Guide
Single dose - 0.05 mg/kg body weight
Route of Administration: Intravenous
Substance Class Chemical
Record UNII
NM87THP11P
Record Status Validated (UNII)
Record Version