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Details

Stereochemistry ACHIRAL
Molecular Formula C6H7NO6.2Na.H2O
Molecular Weight 253.1177
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of DISODIUM NITRILOTRIACETATE MONOHYDRATE

SMILES

O.[Na+].[Na+].OC(=O)CN(CC([O-])=O)CC([O-])=O

InChI

InChIKey=GVFFJAGZCMFNEI-UHFFFAOYSA-L
InChI=1S/C6H9NO6.2Na.H2O/c8-4(9)1-7(2-5(10)11)3-6(12)13;;;/h1-3H2,(H,8,9)(H,10,11)(H,12,13);;;1H2/q;2*+1;/p-2

HIDE SMILES / InChI

Molecular Formula Na
Molecular Weight 22.98976928
Charge 1
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Molecular Formula C6H8NO6
Molecular Weight 190.1308
Charge -1
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Molecular Formula HO
Molecular Weight 17.0073
Charge -1
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Approval Year

PubMed

PubMed

TitleDatePubMed
Synergistic anion and metal binding to the ferric ion-binding protein from Neisseria gonorrhoeae.
2003-01-24
Comparative mutagenicities of bleomycin and ferric-nitrilotriacetate in lacZ mice.
2002-12-10
Simultaneous determination of 3-nitrotyrosine and tyrosine in plasma proteins of rats and assessment of artifactual tyrosine nitration.
2002-11-05
Protective effect of metallothionein-III on DNA damage in response to reactive oxygen species.
2002-10-10
Evaluation of carcinogenic responses in the Eker rat following short-term exposure to selected nephrotoxins and carcinogens.
2002-10-10
Assessment of the ability of the antioxidant cocktail-derived from fermentation of plants with effective microorganisms (EM-X) to modulate oxidative damage in the kidney and liver of rats in vivo: studies upon the profile of poly- and mono-unsaturated fatty acids.
2002-10-05
Adsorption behavior of zinc and cadmium ion on granular activated carbon in singular and binary systems and the influence of nitrilotricetic acid as a complexing agent.
2002-10
pH-Dependent fate and transport of NTA-complexed cobalt through undisturbed cores of fractured shale saprolite.
2002-10
Dissimilatory reduction of Cr(VI), Fe(III), and U(VI) by Cellulomonas isolates.
2002-10
On-column complexation and simultaneous separation of vanadium(IV) and vanadium(V) by capillary electrophoresis with direct UV detection.
2002-10
Correlation between induction of DNA fragmentation in urinary bladder cells from rats and humans and tissue-specific carcinogenic activity.
2002-09-30
Cloning, characterization, and functional studies of a 47-kDa platelet receptor for type III collagen.
2002-09-20
On-column tris(2-carboxyethyl)phosphine reduction and IC5-maleimide labeling during purification of a RpoC fragment on a nickel-nitrilotriacetic acid Column.
2002-08-15
Interferon-alpha enhances biological defense activities against oxidative stress in cultured rat hepatocytes and hepatic stellate cells.
2002-08
Specific binding of integrin alphaIIbbeta3 to RGD peptide immobilized on a nitrilotriacetic acid chip: a surface plasmon resonance study.
2002-08
Effects of phlebotomy on the growth of ferric nitrilotriacetate-induced renal cell carcinoma.
2002-08
Contribution of glutathione and metallothioneins to protection against copper toxicity and redox cycling: quantitative analysis using MT+/+ and MT-/- mouse lung fibroblast cells.
2002-08
Non-transferrin-bound iron in untreated and ribavirin-treated chronic hepatitis C patients.
2002-08
Bioavailability of waterborne strontium to the common carp, Cyprinus carpio, in complexing environments.
2002-08
Development and characterization of Ni-NTA-bearing microspheres.
2002-07-01
Cytotoxic targeting of F9 teratocarcinoma tumours with anti-ED-B fibronectin scFv antibody modified liposomes.
2002-07-01
Purification, reconstitution, and characterization of Na(+)/serine symporter, SstT, of Escherichia coli.
2002-07
Alleviation of the two-cell block of ICR mouse embryos by polyaminocarboxylate metal chelators.
2002-07
Biochemistry and pharmacology of epitope-tagged alpha(1)-adrenergic receptor subtypes.
2002-07
The synergistic anion-binding sites of human transferrin: chemical and physiological effects of site-directed mutagenesis.
2002-06-11
Unusual features for zirconium(IV) binding to human serum transferrin.
2002-06
A novel subtilisin-like serine protease from Thermoanaerobacter yonseiensis KB-1: its cloning, expression, and biochemical properties.
2002-06
The role of metals in site-specific DNA damage with reference to carcinogenesis.
2002-05-01
Protective effect of colored rice over white rice on Fenton reaction-based renal lipid peroxidation in rats.
2002-05
The mechanism of iron uptake by transferrins: the X-ray structures of the 18 kDa NII domain fragment of duck ovotransferrin and its nitrilotriacetate complex.
2002-05
Hydrometallurgical recovery of zinc and lead from electric arc furnace dust using mononitrilotriacetate anion and hexahydrated ferric chloride.
2002-04-26
Comparison of histidine-tag capture chemistries for purification following chemical extraction.
2002-04-12
Carbonic anhydrase inhibitors. A general approach for the preparation of water-soluble sulfonamides incorporating polyamino-polycarboxylate tails and of their metal complexes possessing long-lasting, topical intraocular pressure-lowering properties.
2002-03-28
Relations between clusters of oxidatively damaged nucleotides and active or open nucleosomes in the rat Nth 1 gene.
2002-03-07
Gas chromatographic and mass spectrometric analysis of nitrilotriacetic acid in environmental aqueous samples.
2002-03-07
Nontransferrin-bound iron in the plasma of haemodialysis patients after intravenous iron saccharate infusion.
2002-03
Expression of ayu (Plecoglossus altivelis) Pit-1 in Escherichia coli: its purification and immunohistochemical detection using monoclonal antibody.
2002-03
Overproduction in yeast and rapid and efficient purification of the rabbit SERCA1a Ca(2+)-ATPase.
2002-02-18
Simple cryoprotection and cell dissociation techniques for application of the comet assay to fresh and frozen rat tissues.
2002-02
Specific allelic loss of p16 (INK4A) tumor suppressor gene after weeks of iron-mediated oxidative damage during rat renal carcinogenesis.
2002-02
Oxidative damage and cancer.
2002-02
Bleomycin-detectable iron assay for non-transferrin-bound iron in hematologic malignancies.
2002-02
Potential contact sites between the protein and RNA subunit in the Bacillus subtilis RNase P holoenzyme.
2002-01-25
Iminodiacetate and nitrilotriacetate degradation by Kluyveromyces marxianus IMB3.
2002-01-18
Stimulation and proliferation of primary rat hepatic stellate cells by cytochrome P450 2E1-derived reactive oxygen species.
2002-01
Aqua(nitrilotriacetato)(1,10-phenanthroline)iron(III) monohydrate: a seven-coordinate iron(III) complex.
2002-01
Iron and carcinogenesis: from Fenton reaction to target genes.
2002
Examination of cadmium(II) complexation by the Suwannee River fulvic acid using 113Cd NMR relaxation measurements.
2001-12-15
Assessment of chronic toxicity and carcinogenicity in an accelerated cancer bioassay in rats of moxifloxacin, a quinolone antibiotic.
2001-10
Influence of the glass packing on the contamination of pharmaceutical products by aluminium. Part II: amino acids for parenteral nutrition.
2001
Patents
Substance Class Chemical
Created
by admin
on Mon Mar 31 17:49:33 GMT 2025
Edited
by admin
on Mon Mar 31 17:49:33 GMT 2025
Record UNII
NLA3BW4578
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
DISODIUM NITRILOTRIACETATE MONOHYDRATE
Systematic Name English
ACETIC ACID, NITRILOTRI-, DISODIUM SALT, MONOHYDRATE
Preferred Name English
DISODIUM NITRILOTRIACETIC ACID MONOHYDRATE
Systematic Name English
NTA DISODIUM SALT, MONOHYDRATE
Common Name English
NITRILOTRIACETIC ACID, DISODIUM SALT, MONOHYDRATE
Common Name English
DISODIUM HYDROGEN NITRILOTRIACETATE, MONOHYDRATE
Systematic Name English
GLYCINE, N,N-BIS(CARBOXYMETHYL)-, DISODIUM SALT, MONOHYDRATE
Common Name English
Code System Code Type Description
EPA CompTox
DTXSID80177825
Created by admin on Mon Mar 31 17:49:33 GMT 2025 , Edited by admin on Mon Mar 31 17:49:33 GMT 2025
PRIMARY
PUBCHEM
21116573
Created by admin on Mon Mar 31 17:49:33 GMT 2025 , Edited by admin on Mon Mar 31 17:49:33 GMT 2025
PRIMARY
FDA UNII
NLA3BW4578
Created by admin on Mon Mar 31 17:49:33 GMT 2025 , Edited by admin on Mon Mar 31 17:49:33 GMT 2025
PRIMARY
CAS
23255-03-0
Created by admin on Mon Mar 31 17:49:33 GMT 2025 , Edited by admin on Mon Mar 31 17:49:33 GMT 2025
PRIMARY
Related Record Type Details
PARENT -> SALT/SOLVATE