U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

Details

Stereochemistry ACHIRAL
Molecular Formula C13H12N4S
Molecular Weight 256.326
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 1
Charge 0

SHOW SMILES / InChI
Structure of DITHIZONE

SMILES

S=C(NNC1=CC=CC=C1)\N=N\C2=CC=CC=C2

InChI

InChIKey=UOFGSWVZMUXXIY-BMRADRMJSA-N
InChI=1S/C13H12N4S/c18-13(16-14-11-7-3-1-4-8-11)17-15-12-9-5-2-6-10-12/h1-10,14H,(H,16,18)/b17-15+

HIDE SMILES / InChI

Molecular Formula C13H12N4S
Molecular Weight 256.326
Charge 0
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 1
Optical Activity NONE

Approval Year

PubMed

PubMed

TitleDatePubMed
Effect of metal chelating agents on pentylenetetrazole-induced seizure threshold in cholestatic mice.
2009-01
Computer-assisted digital image analysis to quantify the mass and purity of isolated human islets before transplantation.
2008-12-15
[Research on differentiation features of the monoclonal human pancreatic stem cell].
2008-12
Small interfering RNA-mediated suppression of proislet amyloid polypeptide expression inhibits islet amyloid formation and enhances survival of human islets in culture.
2008-11
Spectrophotometric determination of inorganic mercury (II) after preconcentration of its diphenylthiocarbazone complex on a cellulose column.
2008-10
Establishing a human pancreatic stem cell line and transplanting induced pancreatic islets to reverse experimental diabetes in rats.
2008-09
Spectrophotometric determination of lead after preconcentration of its diphenylthiocarbazone complex on an Amberlite XAD-1180 column.
2008-09
A novel separation/preconcentration system based on solidification of floating organic drop microextraction for determination of lead by graphite furnace atomic absorption spectrometry.
2008-08-15
Adhesive growth of pancreatic islet cells on a polyglycolic acid fibrous scaffold.
2008-06
[An economic and effective method for islet cell isolation from SD rats].
2008-05
Maturation of paneth cells induces the refractory state of newborn mice to Shigella infection.
2008-04-01
[Study on the adsorption capability of barium-strontium titanate powder coated with dithizone for cadmium ion in water].
2008-03
Twenty-four hour hypothermic machine perfusion preservation of porcine pancreas facilitates processing for islet isolation.
2008-03
Method for isolation of mouse pancreatic stem cells.
2008-03
Evaluation of human islet-specific functional quality cultured on different gas-permeable membranes.
2008-03
Human albumin preserves islet mass and function better than whole serum during pretransplantation islet culture.
2008-03
Solid phase extraction and spectrophotometric determination of mercury by adsorption of its diphenylthiocarbazone complex on an alumina column.
2008-02
Armeria maritima from a calamine heap--initial studies on physiologic-metabolic adaptations to metal-enriched soil.
2008-02
[Novel ionic liquid as solvent for preconcentration of trace lead in dialysis fluids and its determination by graphite furnace atomic absorption spectrometry].
2008-01
[Improved method for optimized isolation and purification of rat islets and identification of function].
2008-01
Screening for mercury in aqueous environmental samples and urine samples using thin layer chromatography.
2007-11
Use of a novel medium, the ionic liquid 1-butyl-3-trimethylsilylimidazolium hexafluorophosphate, for liquid-liquid extraction of lead in water and its determination by graphite furnace atomic absorption spectrometry.
2007-09-01
Acinar plasticity: development of a novel in vitro model to study human acinar-to-duct-to-islet differentiation.
2007-05
Ligand displacement, headspace single-drop microextraction, and capillary electrophoresis for the determination of weak acid dissociable cyanide.
2007-04-27
Admicelle-mediated collection followed by flotation for the preconcentration of trace metals in fresh waters.
2007-04-04
A rapid spectrophotometric method for the determination of trace level lead using 1,5-diphenylthiocarbazone in aqueous micellar solutions.
2007-02
Validation and application of an analytical method for monomethylmercury quantification in aquatic plant tissues.
2006-11-24
Fabrication of symmetric hierarchical hollow PbS microcrystals via a facile solvothermal process.
2006-11-16
Methylmercury determination in biological samples using electrothermal atomic absorption spectrometry after acid leaching extraction.
2006-11
Pancreas islet transplantation in the genitourinary tract associated with renal transplantation: an experimental study.
2006-10
Synthesis and application of amberlite XAD-2 functionalized with dithizone for field preconcentration and separation of trace cadmium in seawater.
2006-09
Characterization of pancreatic stem cells derived from adult human pancreas ducts by fluorescence activated cell sorting.
2006-07-28
[Cultivation and identification of pancreatic endocrine progenitor cells].
2006-07-11
Small intestinal submucosa improves islet survival and function in vitro culture.
2006-06
Generation of insulin-secreting cells from human embryonic stem cells.
2006-06
[Determination of lead in water samples by graphite furnace atomic absorption spectrometry after cloud point extraction with dithizone].
2006-05
Induced cell clustering enhances islet beta cell formation from human cultures enriched for pancreatic ductal epithelial cells.
2006-04
Personality traits in miners with past occupational elemental mercury exposure.
2006-02
Determination of Pb(II) with a dithizone-modified carbon paste electrode.
2006
Small intestinal submucosa improves islet survival and function during in vitro culture.
2005-12-14
Sensitized extraction spectrophotometric determination of Hg(II) with dithizone after its flotation as ion-associate using iodide and ferroin.
2005-09-15
Determination of cadmium and lead in table salt by sequential multi-element flame atomic absorption spectrometry.
2005-02-28
Automatic flow procedure based on multicommutation exploiting liquid-liquid extraction for spectrophotometric lead determination in plant material.
2005-02-28
Determination of Lead(II), Copper(II), Zinc(II), Cobalt(II), Cadmium(II), Iron(III), Mercury(II) using sequential injection extractions.
2004-12-15
Exploiting the bead injection concept for sequential determination of copper and mercury ions in river-water samples.
2004-11-15
Determination of platinum and palladium in environmental samples by graphite furnace atomic absorption spectrometry after separation on dithizone sorbent.
2004-09-08
Tandem focused ultrasound (TFU) combined with fast furnace analysis as an improved methodology for total mercury determination in human urine by electrothermal-atomic absorption spectrometry.
2004-09-08
Spectrophotometric study of complexation equilibria with H-point standard addition and H-point curve isolation methods.
2004-01-09
Effect of ethanol in the organic phase on liquid-liquid extraction in monosegmented flow analysis. Determination of zinc in drugs.
2002-03-11
A new method of microvolume back-extraction procedure for enrichment of Pb and Cd and determination by flame atomic absorption spectrometry.
2002-01-04
Patents
Substance Class Chemical
Created
by admin
on Mon Mar 31 21:06:49 GMT 2025
Edited
by admin
on Mon Mar 31 21:06:49 GMT 2025
Record UNII
NJZ2CJ4D6P
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
DITHIZONE
MI  
Common Name English
NSC-215189
Preferred Name English
DIAZENECARBOTHIOIC ACID, 2-PHENYL-, 2-PHENYLHYDRAZIDE
Common Name English
DITHIZONE [MI]
Common Name English
DIPHENYLTHIOCARBAZONE
Systematic Name English
DITHIZONE E-FORM
Common Name English
Code System Code Type Description
EPA CompTox
DTXSID0058770
Created by admin on Mon Mar 31 21:06:49 GMT 2025 , Edited by admin on Mon Mar 31 21:06:49 GMT 2025
PRIMARY
WIKIPEDIA
DITHIZONE
Created by admin on Mon Mar 31 21:06:49 GMT 2025 , Edited by admin on Mon Mar 31 21:06:49 GMT 2025
PRIMARY
MERCK INDEX
m4690
Created by admin on Mon Mar 31 21:06:49 GMT 2025 , Edited by admin on Mon Mar 31 21:06:49 GMT 2025
PRIMARY Merck Index
ECHA (EC/EINECS)
200-454-1
Created by admin on Mon Mar 31 21:06:49 GMT 2025 , Edited by admin on Mon Mar 31 21:06:49 GMT 2025
PRIMARY
NSC
215189
Created by admin on Mon Mar 31 21:06:49 GMT 2025 , Edited by admin on Mon Mar 31 21:06:49 GMT 2025
PRIMARY
CAS
60-10-6
Created by admin on Mon Mar 31 21:06:49 GMT 2025 , Edited by admin on Mon Mar 31 21:06:49 GMT 2025
NON-SPECIFIC STEREOCHEMISTRY
CAS
760132-01-2
Created by admin on Mon Mar 31 21:06:49 GMT 2025 , Edited by admin on Mon Mar 31 21:06:49 GMT 2025
PRIMARY
FDA UNII
NJZ2CJ4D6P
Created by admin on Mon Mar 31 21:06:49 GMT 2025 , Edited by admin on Mon Mar 31 21:06:49 GMT 2025
PRIMARY
MESH
D004230
Created by admin on Mon Mar 31 21:06:49 GMT 2025 , Edited by admin on Mon Mar 31 21:06:49 GMT 2025
PRIMARY
PUBCHEM
657262
Created by admin on Mon Mar 31 21:06:49 GMT 2025 , Edited by admin on Mon Mar 31 21:06:49 GMT 2025
PRIMARY