Details
| Stereochemistry | ACHIRAL |
| Molecular Formula | C17H28N2O2 |
| Molecular Weight | 292.4164 |
| Optical Activity | NONE |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
CCCCNC1=CC=C(C=C1)C(=O)OCCN(CC)CC
InChI
InChIKey=JQMCLLAJJLVYOC-UHFFFAOYSA-N
InChI=1S/C17H28N2O2/c1-4-7-12-18-16-10-8-15(9-11-16)17(20)21-14-13-19(5-2)6-3/h8-11,18H,4-7,12-14H2,1-3H3
| Molecular Formula | C17H28N2O2 |
| Molecular Weight | 292.4164 |
| Charge | 0 |
| Count |
|
| Stereochemistry | ACHIRAL |
| Additional Stereochemistry | No |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Optical Activity | NONE |
DescriptionSources: http://www.genome.jp/dbget-bin/www_bget?dr:D01967https://www.ncbi.nlm.nih.gov/pubmed/26302690Curator's Comment: description was created based on several sources, including:
https://www.ncbi.nlm.nih.gov/pubmed/10551118
Sources: http://www.genome.jp/dbget-bin/www_bget?dr:D01967https://www.ncbi.nlm.nih.gov/pubmed/26302690
Curator's Comment: description was created based on several sources, including:
https://www.ncbi.nlm.nih.gov/pubmed/10551118
p-Butylaminobenzoyldiethylaminoethyl hydrochloride (T-cain) was the most frequently used local anesthetic for spinal anesthesia in Japan in the 1940s–1960s. The market for spinally administered T-cain is almost ended. T-cain is still used for topical/infiltrative anesthesia in some specialties. T-cain may also be used as an alternative in patients who are allergic to lidocaine or bupivacaine. The side effects reported for spinal use of Neo Percamin S (T-cain with dibucaine) were hypotension, bradycardia, respiratory arrest, and allergy.
Originator
Approval Year
PubMed
| Title | Date | PubMed |
|---|---|---|
| [Postoperative pain control after thoracic surgery with depolipone]. | 1955 Jan |
|
| [Clinical results on pulp devitalization of the deciduous teeth with Neoarsen Black]. | 1967 Jun |
|
| Determination of ester-type local anesthetic drugs (procaine, tetracaine, and T-caine) in human serum by wide-bore capillary gas chromatography with nitrogen-phosphorus detection. | 1996 Sep |
|
| Calcium hydroxide pastes: classification and clinical indications. | 1999 Aug |
|
| History of T-cain: a local anesthetic developed and manufactured in Japan. | 2015 Oct |
| Substance Class |
Chemical
Created
by
admin
on
Edited
Sat Dec 16 01:36:21 UTC 2023
by
admin
on
Sat Dec 16 01:36:21 UTC 2023
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| Record UNII |
NGB06K86SA
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| Record Status |
Validated (UNII)
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3772-42-7
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NGB06K86SA
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4651
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DTXSID90191153
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admin on Sat Dec 16 01:36:21 UTC 2023 , Edited by admin on Sat Dec 16 01:36:21 UTC 2023
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| Related Record | Type | Details | ||
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SALT/SOLVATE -> PARENT |
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