Details
| Stereochemistry | ACHIRAL |
| Molecular Formula | C17H28N2O2 |
| Molecular Weight | 292.4164 |
| Optical Activity | NONE |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
CCCCNC1=CC=C(C=C1)C(=O)OCCN(CC)CC
InChI
InChIKey=JQMCLLAJJLVYOC-UHFFFAOYSA-N
InChI=1S/C17H28N2O2/c1-4-7-12-18-16-10-8-15(9-11-16)17(20)21-14-13-19(5-2)6-3/h8-11,18H,4-7,12-14H2,1-3H3
| Molecular Formula | C17H28N2O2 |
| Molecular Weight | 292.4164 |
| Charge | 0 |
| Count |
|
| Stereochemistry | ACHIRAL |
| Additional Stereochemistry | No |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Optical Activity | NONE |
DescriptionSources: https://www.ncbi.nlm.nih.gov/pubmed/26302690http://www.genome.jp/dbget-bin/www_bget?dr:D01967Curator's Comment: https://www.ncbi.nlm.nih.gov/pubmed/14304485;
https://www.ncbi.nlm.nih.gov/pubmed/8872242; https://www.ncbi.nlm.nih.gov/pubmed/?term=13747914; https://www.jstage.jst.go.jp/article/bpb/39/3/39_b15-00380/_html
Sources: https://www.ncbi.nlm.nih.gov/pubmed/26302690http://www.genome.jp/dbget-bin/www_bget?dr:D01967
Curator's Comment: https://www.ncbi.nlm.nih.gov/pubmed/14304485;
https://www.ncbi.nlm.nih.gov/pubmed/8872242; https://www.ncbi.nlm.nih.gov/pubmed/?term=13747914; https://www.jstage.jst.go.jp/article/bpb/39/3/39_b15-00380/_html
2-Diethylaminoethyl 4-Butylaminobenzoate (farmocaine, T-caine) is an ester-type local anesthetic drug. Like all ester-type local anesthetic drugs farmocaine is very unstable in the body, and in humans they are rapidly hydrolyzed in the plasma. No direct correlation between the saponification and biological activity of farmocaine and similar local anesthetic esters was found. T-Caine has been used as a spray anesthetization of the throat and as a component of Neoarsen black, Neo-percamin S, topical Neozalocain(R) pasta (benzocaine and farmocaine, Neo Dental Chemical Products, Osaka, Japan) and as a calvital powder in dentistry.
Originator
Approval Year
PubMed
| Title | Date | PubMed |
|---|---|---|
| History of T-cain: a local anesthetic developed and manufactured in Japan. | 2015-10 |
|
| Calcium hydroxide pastes: classification and clinical indications. | 1999-08 |
|
| Determination of ester-type local anesthetic drugs (procaine, tetracaine, and T-caine) in human serum by wide-bore capillary gas chromatography with nitrogen-phosphorus detection. | 1996-09 |
|
| Fluid behavior of root canal paste (Part 2). Fluid behavior of Calvital. | 1985-06 |
|
| [Clinical results on pulp devitalization of the deciduous teeth with Neoarsen Black]. | 1967-06 |
|
| [Postoperative pain control after thoracic surgery with depolipone]. | 1955-01 |
| Substance Class |
Chemical
Created
by
admin
on
Edited
Mon Mar 31 20:55:05 GMT 2025
by
admin
on
Mon Mar 31 20:55:05 GMT 2025
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| Record UNII |
NGB06K86SA
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| Record Status |
Validated (UNII)
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| Record Version |
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3772-42-7
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NGB06K86SA
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4651
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DTXSID90191153
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admin on Mon Mar 31 20:55:05 GMT 2025 , Edited by admin on Mon Mar 31 20:55:05 GMT 2025
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| Related Record | Type | Details | ||
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SALT/SOLVATE -> PARENT |
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