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Approval Year

Substance Class Protein
Created
by admin
on Sat Dec 16 16:11:13 GMT 2023
Edited
by admin
on Sat Dec 16 16:11:13 GMT 2023
Protein Type PEPTIDE
Protein Sub Type
Sequence Origin HUMAN
Sequence Type COMPLETE
Record UNII
NFZ9GEM9QP
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
HUMAN .BETA.-AMYLOID PEPTIDE (PGLU3-40)
Common Name English
PGLU-A.BETA.(3-40)
Common Name English
Code System Code Type Description
FDA UNII
NFZ9GEM9QP
Created by admin on Sat Dec 16 16:11:13 GMT 2023 , Edited by admin on Sat Dec 16 16:11:13 GMT 2023
PRIMARY
Related Record Type Details
INHIBITOR OF AGGREGATION->TARGET
AβpE is of interest as it has been shown to be one of the dominant forms of Aβ present in the hippocampi and cortices of patients with Alzheimer's disease. However, arguably of most importance is that AβpE is specifically only found within cerebral Aβ plaques.2 In-vitro analysis has revealed that AβpE3 shows an increased rate of aggregation up to 250 times that of full-length Aβ, irrespective of its C terminus.
INHIBITOR OF EXPRESSION->TARGET
Name Property Type Amount Referenced Substance Defining Parameters References
MOL_WEIGHT:NUMBER(CALCULATED) CHEMICAL