.ALPHA.-METHYLTHIOFENTANYL

U.S. Department of Health & Human Services Divider Arrow

National Institutes of Health Divider Arrow

NCATS

Details

Stereochemistry	RACEMIC
Molecular Formula	C21H28N2OS
Molecular Weight	356.525
Optical Activity	( + / - )
Defined Stereocenters	0 / 1
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure of .ALPHA.-METHYLTHIOFENTANYL

Structure Search

SMILES

CCC(=O)N(C1CCN(CC1)C(C)CC2=CC=CS2)C3=CC=CC=C3

InChI

InChIKey=YPOXDUYRRSUFFG-UHFFFAOYSA-N

InChI=1S/C21H28N2OS/c1-3-21(24)23(18-8-5-4-6-9-18)19-11-13-22(14-12-19)17(2)16-20-10-7-15-25-20/h4-10,15,17,19H,3,11-14,16H2,1-2H3

HIDE SMILES / InChI

Molecular Formula	C21H28N2OS
Molecular Weight	356.525
Charge	0
Count

Stereochemistry	RACEMIC
Additional Stereochemistry	No
Defined Stereocenters	0 / 1
E/Z Centers	0
Optical Activity	( + / - )

Approval Year

Targets

Targets

Primary Target	Pharmacology	Condition	Potency
Mu opioid receptor 231 Target ID: CHEMBL233 Sources: https://arxiv.org/ftp/arxiv/papers/1803/1803.04479.pdf	Agonist 2752

Patents

Patents

Substance Class	Chemical Created by `admin` on `Mon Mar 31 22:47:05 GMT 2025` Edited by `admin` on `Mon Mar 31 22:47:05 GMT 2025`
Record UNII	NF684LIF79
Record Status	`Validated (UNII)`
Record Version

Download

Name

Type

Language

.ALPHA.-METHYLTHIOFENTANYL

Common Name

English

IDS-NA-017

Preferred Name

English

PROPANAMIDE, N-(1-(1-METHYL-2-(2-THIENYL)ETHYL)-4-PIPERIDINYL)-N-PHENYL-

Systematic Name

English

ALPHA-METHYLTHIOFENTANYL

Common Name

English

IDS-NA-017(SECT.3)

Code

English

ACSCN-9832

Common Name

English

.ALPHA.-METHYL-THIOFENTANYL

Common Name

English

N-(1-(1-METHYL-2-(2-THIENYL)ETHYL)-4-PIPERIDYL)PROPIONANILIDE

Systematic Name

English

Classification Tree Code System Code

WIKIPEDIA

List_of_fentanyl_analogues

Created by admin on Mon Mar 31 22:47:05 GMT 2025 , Edited by admin on Mon Mar 31 22:47:05 GMT 2025

DEA NO.

9832

Created by admin on Mon Mar 31 22:47:05 GMT 2025 , Edited by admin on Mon Mar 31 22:47:05 GMT 2025

Code System Code Type Description

CAS

103963-66-2

Created by admin on Mon Mar 31 22:47:05 GMT 2025 , Edited by admin on Mon Mar 31 22:47:05 GMT 2025

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EPA CompTox

DTXSID90861243

Created by admin on Mon Mar 31 22:47:05 GMT 2025 , Edited by admin on Mon Mar 31 22:47:05 GMT 2025

PRIMARY

WEB RESOURCE

.ALPHA.-METHYL-THIOFENTANYL

Created by admin on Mon Mar 31 22:47:05 GMT 2025 , Edited by admin on Mon Mar 31 22:47:05 GMT 2025

PRIMARY

FDA UNII

NF684LIF79

Created by admin on Mon Mar 31 22:47:05 GMT 2025 , Edited by admin on Mon Mar 31 22:47:05 GMT 2025

PRIMARY

DRUG BANK

DB01470

Created by admin on Mon Mar 31 22:47:05 GMT 2025 , Edited by admin on Mon Mar 31 22:47:05 GMT 2025

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WIKIPEDIA

Alphamethylthiofentanyl

Created by admin on Mon Mar 31 22:47:05 GMT 2025 , Edited by admin on Mon Mar 31 22:47:05 GMT 2025

PRIMARY

.ALPHA.-methyl-thiofentanyl has similar effects to fentanyl. Side effects of fentanyl analogs are similar to those of fentanyl itself, which include itching, nausea and potentially serious respiratory depression, which can be life-threatening. Fentanyl analogs have killed hundreds of people throughout Europe and the former Soviet republics since the most recent resurgence in use began in Estonia in the early 2000s, and novel derivatives continue to appear.

PUBCHEM

62309

Created by admin on Mon Mar 31 22:47:05 GMT 2025 , Edited by admin on Mon Mar 31 22:47:05 GMT 2025

PRIMARY

Related Record Type Details


					2DZ62M473M

.ALPHA. METHYLTHIOFENTANYL HYDROCHLORIDE

SALT/SOLVATE -> PARENT

Amount:


					2DZ62M473M

.ALPHA. METHYLTHIOFENTANYL HYDROCHLORIDE

SALT/SOLVATE -> PARENT

Comments:

APPROXIMATE PURE ANHYDROUS DRUG CONTENT (IN PERCENT)

Amount:


					1PE72K8X46

MU-TYPE OPIOID RECEPTOR

TARGET -> AGONIST

Related Record Type Details


					NF684LIF79

.ALPHA.-METHYLTHIOFENTANYL

ACTIVE MOIETY