Tyrphostin AG-1024

Details

Stereochemistry	ACHIRAL
Molecular Formula	C14H13BrN2O
Molecular Weight	305.17
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

CC(C)(C)C1=CC(C=C(C#N)C#N)=CC(Br)=C1O

InChI

InChIKey=ABBADGFSRBWENF-UHFFFAOYSA-N

InChI=1S/C14H13BrN2O/c1-14(2,3)11-5-9(4-10(7-16)8-17)6-12(15)13(11)18/h4-6,18H,1-3H3

HIDE SMILES / InChI

Molecular Formula	C14H13BrN2O
Molecular Weight	305.17
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Approval Year

Targets

Primary Target	Pharmacology	Condition	Potency
Insulin-like growth factor 1 receptor 4 Target ID: P08069 Gene ID: 3480.0 Gene Symbol: IGF1R Target Organism: Homo sapiens (Human) Sources: https://www.ncbi.nlm.nih.gov/pubmed/9075698	Inhibitor 8504		7.0 µM [IC50]
Insulin receptor 13 Target ID: P06213 Gene ID: 3643.0 Gene Symbol: INSR Target Organism: Homo sapiens (Human) Sources: https://www.ncbi.nlm.nih.gov/pubmed/9075698	Inhibitor 8504		57.0 µM [IC50]

PubMed

Title	Date	PubMed

Substance Class	Chemical Created by `admin` on `Tue Apr 01 19:01:26 GMT 2025` Edited by `admin` on `Tue Apr 01 19:01:26 GMT 2025`
Record UNII	NF4XN6A8V9
Record Status	`Validated (UNII)`
Record Version

Download

Name

Type

Language

Tyrphostin AG-1024

Common Name

English

AG-1024

Preferred Name

English

2-[(3-Bromo-5-tert-butyl-4-hydroxyphenyl)methylidene]propanedinitrile

Systematic Name

English

AGS-200

Code

English

Propanedinitrile, 2-[[3-bromo-5-(1,1-dimethylethyl)-4-hydroxyphenyl]methylene]-

Systematic Name

English

2-[[3-Bromo-5-(1,1-dimethylethyl)-4-hydroxyphenyl]methylene]propanedinitrile

Systematic Name

English

Code System Code Type Description

PUBCHEM

2044

Created by admin on Tue Apr 01 19:01:26 GMT 2025 , Edited by admin on Tue Apr 01 19:01:26 GMT 2025

PRIMARY

FDA UNII

NF4XN6A8V9

Created by admin on Tue Apr 01 19:01:26 GMT 2025 , Edited by admin on Tue Apr 01 19:01:26 GMT 2025

PRIMARY

EPA CompTox

DTXSID50274350

Created by admin on Tue Apr 01 19:01:26 GMT 2025 , Edited by admin on Tue Apr 01 19:01:26 GMT 2025

PRIMARY

CAS

65678-07-1

Created by admin on Tue Apr 01 19:01:26 GMT 2025 , Edited by admin on Tue Apr 01 19:01:26 GMT 2025

PRIMARY

Related Record Type Details


					ORH3YB25JY

SERINE/THREONINE-PROTEIN KINASE N2

TARGET -> INHIBITOR