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Details

Stereochemistry ACHIRAL
Molecular Formula C17H23NOS2
Molecular Weight 321.501
Optical Activity UNSPECIFIED
Defined Stereocenters 2 / 2
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of THIHEXINOL

SMILES

CN(C)[C@H]1CC[C@@H](CC1)C(O)(C2=CC=CS2)C3=CC=CS3

InChI

InChIKey=LDMSODJIMDPNOG-HDJSIYSDSA-N
InChI=1S/C17H23NOS2/c1-18(2)14-9-7-13(8-10-14)17(19,15-5-3-11-20-15)16-6-4-12-21-16/h3-6,11-14,19H,7-10H2,1-2H3/t13-,14-

HIDE SMILES / InChI

Molecular Formula C17H23NOS2
Molecular Weight 321.501
Charge 0
Count
Stereochemistry ABSOLUTE
Additional Stereochemistry No
Defined Stereocenters 2 / 2
E/Z Centers 0
Optical Activity UNSPECIFIED

THIHEXINOL is a parasympatholytic or anticholinergic drug used for symptomatic treatment of diarrhea in combination, also known as Sorboquel, with a water-adsorbing synthetic polycarboxylic resin polycarbophil.

Approval Year

Conditions

Conditions

ConditionModalityTargetsHighest PhaseProduct
Primary
Sorboquel

Approved Use

Unknown
Primary
Sorboquel

Approved Use

Unknown
PubMed

PubMed

TitleDatePubMed
Observations on the use of sorboquel in chronic diarrhea.
1960 Nov
Effects of combined polycarbophil-thihexinol and neomycin in acute diarrheas: experimental and clinical observations.
1963 Jul
Diarrhea and its management, with special reference to polycarbophil-thihexinol-neomycin therapy.
1963 Jun
DRUGS USED IN THE SYMPTOMATIC TREATMENT OF DIARRHEA.
1964 Oct 31

Sample Use Guides

The usial adult dose is one tablet four times a day.
Route of Administration: Oral
Substance Class Chemical
Created
by admin
on Sat Dec 16 08:26:50 GMT 2023
Edited
by admin
on Sat Dec 16 08:26:50 GMT 2023
Record UNII
NDG7P9Y3TF
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
THIHEXINOL
Common Name English
2-THIOPHENEMETHANOL, .ALPHA.-(TRANS-4-(DIMETHYLAMINO)CYCLOHEXYL)-.ALPHA.-2-THIENYL-
Systematic Name English
Code System Code Type Description
CAS
845713-32-8
Created by admin on Sat Dec 16 08:26:50 GMT 2023 , Edited by admin on Sat Dec 16 08:26:50 GMT 2023
PRIMARY
PUBCHEM
20055051
Created by admin on Sat Dec 16 08:26:50 GMT 2023 , Edited by admin on Sat Dec 16 08:26:50 GMT 2023
PRIMARY
FDA UNII
NDG7P9Y3TF
Created by admin on Sat Dec 16 08:26:50 GMT 2023 , Edited by admin on Sat Dec 16 08:26:50 GMT 2023
PRIMARY