HT-2 TOXIN

Details

Stereochemistry	ABSOLUTE
Molecular Formula	C22H32O8
Molecular Weight	424.4847
Optical Activity	UNSPECIFIED
Defined Stereocenters	8 / 8
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

[H][C@@]12O[C@]3([H])C=C(C)[C@H](C[C@]3(COC(C)=O)[C@@](C)([C@H](O)[C@H]1O)[C@]24CO4)OC(=O)CC(C)C

InChI

InChIKey=PNKLMTPXERFKEN-MLXHEQMXSA-N

InChI=1S/C22H32O8/c1-11(2)6-16(24)29-14-8-21(9-27-13(4)23)15(7-12(14)3)30-19-17(25)18(26)20(21,5)22(19)10-28-22/h7,11,14-15,17-19,25-26H,6,8-10H2,1-5H3/t14-,15+,17+,18+,19+,20+,21+,22-/m0/s1

HIDE SMILES / InChI

Molecular Formula	C22H32O8
Molecular Weight	424.4847
Charge	0
Count

Stereochemistry	ABSOLUTE
Additional Stereochemistry	No
Defined Stereocenters	8 / 8
E/Z Centers	0
Optical Activity	UNSPECIFIED

Approval Year

Targets

Primary Target	Pharmacology	Condition	Potency
Apoptosis 155 Target ID: map04210 Sources: https://www.ncbi.nlm.nih.gov/pubmed/31072003	Activator 1430
autophagy 17 Target ID: GO:0006914 Sources: https://www.ncbi.nlm.nih.gov/pubmed/31072003	Activator 1430

PubMed

Title	Date	PubMed
Matrix binding of T-2 toxin: structure elucidation of reaction products and indications on the fate of a relevant food-borne toxin during heating.	2019 Aug	30903560
Fluorescence Polarization Immunoassay for the Determination of T-2 and HT-2 Toxins and Their Glucosides in Wheat.	2019 Jul 1	31266143
Mycotoxins' evaluation in wheat flours used in Brazilian bakeries.	2019 Jun	31093452
Occurrence of Mycotoxins in Swine Feeding from Spain.	2019 Jun 15	31208034
Effect of storage conditions on the formation of type A and B trichothecenes in cereal products.	2019 Jun 17	31232057
Study on Trichothecene and Zearalenone Presence in Romanian Wheat Relative to Weather Conditions.	2019 Mar 15	30875933
Mycotoxins at the Start of the Food Chain in Costa Rica: Analysis of Six Fusarium Toxins and Ochratoxin A between 2013 and 2017 in Animal Feed and Aflatoxin M(1) in Dairy Products.	2019 May 31	31159287
Occurrence and Risk Assessment of Mycotoxins through Polish Beer Consumption.	2019 May 7	31067689
Comparison of Apoptosis and Autophagy in Human Chondrocytes Induced by the T-2 and HT-2 Toxins.	2019 May 8	31072003
Combined hazard assessment of mycotoxins and their modified forms applying relative potency factors: Zearalenone and T2/HT2 toxin.	2019 Sep	31247258

Substance Class	Chemical Created by `admin` on `Sat Dec 16 08:53:55 GMT 2023` Edited by `admin` on `Sat Dec 16 08:53:55 GMT 2023`
Record UNII	NC6C26RM46
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

HT-2 TOXIN

Common Name

English

TRICHOTHEC-9-ENE-3,4,8,15-TETROL, 12,13-EPOXY-, 15-ACETATE 8-(3-METHYLBUTANOATE), (3.ALPHA.,4.BETA.,8.ALPHA.)-

Systematic Name

English

3,4-DIHYDROXY-15-ACETOXY-8-(3-METHYLBUTYRYLOXY)-12,13-EPOXY-.DELTA.9-TRICHOTHECENE

Systematic Name

English

TOXIN HT 2

Common Name

English

NSC-278571

Code

English

Code System Code Type Description

CHEBI

138861