1,7-NAPHTHYRIDINE

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NCATS

Details

Stereochemistry	ACHIRAL
Molecular Formula	C8H6N2
Molecular Weight	130.1466
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure of 1,7-NAPHTHYRIDINE

Structure Search

SMILES

C1=CC2=CC=NC=C2N=C1

InChI

InChIKey=MXBVNILGVJVVMH-UHFFFAOYSA-N

InChI=1S/C8H6N2/c1-2-7-3-5-9-6-8(7)10-4-1/h1-6H

HIDE SMILES / InChI

Molecular Formula	C8H6N2
Molecular Weight	130.1466
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Approval Year

PubMed

PubMed

Title	Date	PubMed
Aminopyrazine inhibitors binding to an unusual inactive conformation of the mitotic kinase Nek2: SAR and structural characterization.	2010-11-11	20936789
Syntheses and EGFR kinase inhibitory activity of 6-substituted-4-anilino [1,7] and [1,8] naphthyridine-3-carbonitriles.	2004-03-22	15006373
Pharmacological profile of a novel phosphodiesterase 4 inhibitor, 4-(8-benzo[1,2,5]oxadiazol-5-yl-[1,7]naphthyridin-6-yl)-benzoic acid (NVP-ABE171), a 1,7-naphthyridine derivative, with anti-inflammatory activities.	2002-04	11907180
Synthesis of 4-(8-benzo[1,2,5]oxadiazol-5-yl-[1,7]naphthyridine-6-yl)-benzoic acid: a potent and selective phosphodiesterase type 4D inhibitor.	2002-01-21	11755362

Substance Class	Chemical Created by `admin` on `Mon Mar 31 19:45:52 GMT 2025` Edited by `admin` on `Mon Mar 31 19:45:52 GMT 2025`
Record UNII	NA3KH11MLA
Record Status	`Validated (UNII)`
Record Version

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Name

Type

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1,7-NAPHTHYRIDINE

Preferred Name

English

Code System Code Type Description

CAS

253-69-0

Created by admin on Mon Mar 31 19:45:52 GMT 2025 , Edited by admin on Mon Mar 31 19:45:52 GMT 2025

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CHEBI

36626

Created by admin on Mon Mar 31 19:45:52 GMT 2025 , Edited by admin on Mon Mar 31 19:45:52 GMT 2025

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EPA CompTox

DTXSID20179944

Created by admin on Mon Mar 31 19:45:52 GMT 2025 , Edited by admin on Mon Mar 31 19:45:52 GMT 2025

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FDA UNII

NA3KH11MLA

Created by admin on Mon Mar 31 19:45:52 GMT 2025 , Edited by admin on Mon Mar 31 19:45:52 GMT 2025

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PUBCHEM

9209

Created by admin on Mon Mar 31 19:45:52 GMT 2025 , Edited by admin on Mon Mar 31 19:45:52 GMT 2025

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