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Details

Stereochemistry ACHIRAL
Molecular Formula H3O4P
Molecular Weight 98.9953
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of PHOSPHORIC ACID P-32

SMILES

O[32P](O)(O)=O

InChI

InChIKey=NBIIXXVUZAFLBC-HOSYLAQJSA-N
InChI=1S/H3O4P/c1-5(2,3)4/h(H3,1,2,3,4)/i5+1

HIDE SMILES / InChI

Molecular Formula H3O4P
Molecular Weight 98.9953
Charge 0
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

P-32 is a radioactive isotope of phosphorus with a half-life of 14.29 days. Radioactive decay of P-32 produces beta-particles (electrons) which are able to penetrate tissue at a range of 3-8 mm. Phosphate ion P-32 has many applications in medicine and biology. P32 sodium phosphate was approved by the FDA for the treatment of polycythemia vera, chronic myelocytic leukemia, and chronic lymphocytic leukemia. P32-phosphate may also be used in the palliative treatment of selected patients with multiple areas of skeletal metastases. As metabolic uptake of phosphorus is selectively increased in malignant tissues, P-32 was also used for cancer diagnostics.

Approval Year

Conditions

Conditions

ConditionModalityTargetsHighest PhaseProduct
Primary
SODIUM PHOSPHATE P 32

Approved Use

P32 sodium phosphate is indicated for the treatment of polycythemia vera and is effective for the treatment of chronic myelocytic leukemia and chronic lymphocytic leukemia. It may also be used in the palliative treatment of selected patients with multiple areas of skeletal metastases

Launch Date

1959
Primary
SODIUM PHOSPHATE P 32

Approved Use

P32 sodium phosphate is indicated for the treatment of polycythemia vera and is effective for the treatment of chronic myelocytic leukemia and chronic lymphocytic leukemia. It may also be used in the palliative treatment of selected patients with multiple areas of skeletal metastases

Launch Date

1959
Primary
SODIUM PHOSPHATE P 32

Approved Use

P32 sodium phosphate is indicated for the treatment of polycythemia vera and is effective for the treatment of chronic myelocytic leukemia and chronic lymphocytic leukemia. It may also be used in the palliative treatment of selected patients with multiple areas of skeletal metastases

Launch Date

1959
PubMed

PubMed

TitleDatePubMed
EANM procedure guideline for 32P phosphate treatment of myeloproliferative diseases.
2007 Aug
Substance Class Chemical
Created
by admin
on Sat Dec 16 00:28:20 GMT 2023
Edited
by admin
on Sat Dec 16 00:28:20 GMT 2023
Record UNII
N9H3ZTX0BG
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
PHOSPHORIC ACID P-32
Common Name English
(32P)PHOSPHORIC ACID
Common Name English
32P-ORTHOPHOSPHORIC ACID
Common Name English
PHOSPHORIC-32P ACID
Common Name English
Code System Code Type Description
FDA UNII
N9H3ZTX0BG
Created by admin on Sat Dec 16 00:28:20 GMT 2023 , Edited by admin on Sat Dec 16 00:28:20 GMT 2023
PRIMARY
CAS
15364-02-0
Created by admin on Sat Dec 16 00:28:20 GMT 2023 , Edited by admin on Sat Dec 16 00:28:20 GMT 2023
PRIMARY
PUBCHEM
71181
Created by admin on Sat Dec 16 00:28:20 GMT 2023 , Edited by admin on Sat Dec 16 00:28:20 GMT 2023
PRIMARY