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Details

Stereochemistry EPIMERIC
Molecular Formula C24H29N5O4
Molecular Weight 451.5191
Optical Activity UNSPECIFIED
Defined Stereocenters 1 / 2
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of VALERYL-4-HYDROXYVALSARTAN

SMILES

CC(C)[C@@]([H])(C(=O)O)N(Cc1ccc(cc1)-c2ccccc2-c3n[nH]nn3)C(=O)CCC([H])(C)O

InChI

InChIKey=ICSQZMPILLPFKC-XLDIYJRPSA-N
InChI=1S/C24H29N5O4/c1-15(2)22(24(32)33)29(21(31)13-8-16(3)30)14-17-9-11-18(12-10-17)19-6-4-5-7-20(19)23-25-27-28-26-23/h4-7,9-12,15-16,22,30H,8,13-14H2,1-3H3,(H,32,33)(H,25,26,27,28)/t16?,22-/m0/s1

HIDE SMILES / InChI

Molecular Formula C24H29N5O4
Molecular Weight 451.5191
Charge 0
Count
Stereochemistry EPIMERIC
Additional Stereochemistry No
Defined Stereocenters 1 / 2
E/Z Centers 0
Optical Activity UNSPECIFIED

Approval Year

PubMed

PubMed

TitleDatePubMed
Effects of valsartan and valeryl 4-hydroxy valsartan on human platelets: a possible additional mechanism for clinical benefits.
2004 May
Optimization via experimental design of an SPE-HPLC-UV-fluorescence method for the determination of valsartan and its metabolite in human plasma samples.
2006 Oct
Biovalidation of an SPE-HPLC-UV-fluorescence method for the determination of valsartan and its metabolite valeryl-4-hydroxy-valsartan in human plasma.
2007 Sep
Substance Class Chemical
Created
by admin
on Sat Jun 26 11:19:59 UTC 2021
Edited
by admin
on Sat Jun 26 11:19:59 UTC 2021
Record UNII
N891C54AXX
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
VALERYL-4-HYDROXYVALSARTAN
Common Name English
CGP-71580
Code English
L-VALINE, N-(4-HYDROXY-1-OXOPENTYL)-N-((2'-(2H-TETRAZOL-5-YL)(1,1'-BIPHENYL)-4-YL)METHYL)-
Systematic Name English
Code System Code Type Description
FDA UNII
N891C54AXX
Created by admin on Sat Jun 26 11:19:59 UTC 2021 , Edited by admin on Sat Jun 26 11:19:59 UTC 2021
PRIMARY
PUBCHEM
9911647
Created by admin on Sat Jun 26 11:19:59 UTC 2021 , Edited by admin on Sat Jun 26 11:19:59 UTC 2021
PRIMARY
CAS
188259-69-0
Created by admin on Sat Jun 26 11:19:59 UTC 2021 , Edited by admin on Sat Jun 26 11:19:59 UTC 2021
PRIMARY
Related Record Type Details
PARENT -> METABOLITE INACTIVE
Valsartan was metabolized to a small extent only. The only notable metabolite in plasma, urine and faecs
MAJOR
FECAL; PLASMA; URINE