U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

Approval Year

Substance Class Protein
Created
by admin
on Sat Jun 26 17:20:56 UTC 2021
Edited
by admin
on Sat Jun 26 17:20:56 UTC 2021
Protein Type MONOCLONAL ANTIBODY
Protein Sub Type IGG1
Sequence Origin HUMAN
Record UNII
N7Q9NLF11I
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
LY-3832479
Preferred Name English
ETESEVIMAB
USAN   INN  
Official Name English
ANTI-SARS-COV-2 ANTIBODY JS016
Common Name English
CB6
Code English
JS016
Code English
NP-005
Code English
LY COV016
Code English
LY3832479
Code English
IMMUNOGLOBULIN G1*03-KAPPA, ANTI-(SEVERE ACUTE RESPIRATORY SYNDROME CORONAVIRUS 2 SPIKE GLYCOPROTEIN (PEPLOMER PROTEIN, E2))HUMAN MONOCLONAL ANTIBODY.GAMMA.1 HEAVY CHAIN (1-449) (HOMO SAPIENS VH (IGHV3-66*01 (97%) (IGHD)-IGHJ4*01 (93%)) (8.7.13) (1-119)-
Common Name English
CB-6
Code English
JS-016
Code English
ETESEVIMAB [INN]
Common Name English
ETESEVIMAB [WHO-DD]
Common Name English
ETESEVIMAB [USAN]
Common Name English
IMMUNOGLOBULIN G1 (236-ALANINE,237-ALANINE), ANTI-(SEVERE ACUTE RESPIRATORY SYNDROME CORONAVIRUS 2 SPIKE GLYCOPROTEIN RECEPTOR-BINDING DOMAIN) (HUMAN MONOCLONAL JS016 .GAMMA.1-CHAIN), DISULFIDE WITH HUMAN MONOCLONAL JS016 .KAPPA.-CHAIN, DIMER
Common Name English
IMMUNOGLOBULIN G1 (236-ALANINE,237-ALANINE), ANTI-(SEVERE ACUTE RESPIRATORY SYNDROME CORONAVIRUS 2 SPIKE GLYCOPROTEIN) (HUMAN MONOCLONAL LY3832479 .GAMMA.1-CHAIN), DISULFIDE WITH HUMAN MONOCLONAL LY3832479 .KAPPA.-CHAIN, DIMER
Common Name English
NP005
Code English
LY-COV016
Code English
Code System Code Type Description
CAS
2423948-94-9
Created by admin on Sat Jun 26 17:20:56 UTC 2021 , Edited by admin on Sat Jun 26 17:20:56 UTC 2021
PRIMARY
INN
11873
Created by admin on Sat Jun 26 17:20:56 UTC 2021 , Edited by admin on Sat Jun 26 17:20:56 UTC 2021
PRIMARY
FDA UNII
N7Q9NLF11I
Created by admin on Sat Jun 26 17:20:56 UTC 2021 , Edited by admin on Sat Jun 26 17:20:56 UTC 2021
PRIMARY
NCI_THESAURUS
C173977
Created by admin on Sat Jun 26 17:20:56 UTC 2021 , Edited by admin on Sat Jun 26 17:20:56 UTC 2021
PRIMARY
From To
4_136 4_196
4_23 4_88
3_136 3_196
3_23 3_88
2_369 2_427
2_263 2_323
2_222 4_216
2_146 2_202
2_22 2_95
1_369 1_427
1_263 1_323
1_231 2_231
1_228 2_228
1_222 3_216
1_146 1_202
1_22 1_95
Glycosylation Type MAMMALIAN
Glycosylation Link Type Site
N 1_299
N 2_299
Related Record Type Details
TARGET->LIGAND
Blocks attachment of the virus to human angiotensin-converting enzyme 2 (ACE2) receptors, preventing subsequent viral entry into human cells and viral replication.
TARGET ORGANISM->INHIBITOR
Related Record Type Details
ACTIVE MOIETY
Name Property Type Amount Referenced Substance Defining Parameters References
MOL_WEIGHT:NUMBER(CALCULATED) CHEMICAL
Molecular Formula CHEMICAL