CAFFEIC ACID METHYL ESTER

COC(=O)\C=C\C1=CC(O)=C(O)C=C1

InChIKey=OCNYGKNIVPVPPX-HWKANZROSA-N

InChI=1S/C10H10O4/c1-14-10(13)5-3-7-2-4-8(11)9(12)6-7/h2-6,11-12H,1H3/b5-3+

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	1
Optical Activity	NONE

Targets

Primary Target	Pharmacology	Potency
Sucrase-isomaltase 5 Target ID: CHEMBL3114 Sources: https://www.ncbi.nlm.nih.gov/pubmed/20378981	Inhibitor 8297	1.5 mM [IC50]
Protein tyrosine kinase 1 Target ID: Protein tyrosine kinase Sources: https://www.ncbi.nlm.nih.gov/pubmed/1423745	Inhibitor 8297
Ornithine decarboxylase 15 Target ID: CHEMBL1869 Sources: https://www.ncbi.nlm.nih.gov/pubmed/1423745	Inhibitor 8297

PubMed

Title	Date	PubMed
Synthesis of trans-caffeate analogues and their bioactivities against HIV-1 integrase and cancer cell lines.	2008 Dec 15	18952420
Activity of caffeic acid derivatives against Candida albicans biofilm.	2014 Mar 15	24582984
K20E, an oxidative-coupling compound of methyl caffeate, exhibits anti-angiogenic activities through down-regulations of VEGF and VEGF receptor-2.	2015 Jan 15	25481497

Patents

Substance Class	Chemical Created by `admin` on `Fri Dec 15 17:50:48 GMT 2023` Edited by `admin` on `Fri Dec 15 17:50:48 GMT 2023`
Record UNII	N79173B9HF
Record Status	`Validated (UNII)`
Record Version

Name

Type

Language

CAFFEIC ACID METHYL ESTER

Common Name

English

METHYL CAFFEATE

Common Name

English

CINNAMIC ACID, 3,4-DIHYDROXY-, METHYL ESTER

Systematic Name

English

METHYL-3,4-DIHYDROXY CINNAMATE

Common Name

English

Code System Code Type Description

EPA CompTox

DTXSID401030290