CAFFEIC ACID METHYL ESTER

COC(=O)\C=C\C1=CC(O)=C(O)C=C1

InChIKey=OCNYGKNIVPVPPX-HWKANZROSA-N

InChI=1S/C10H10O4/c1-14-10(13)5-3-7-2-4-8(11)9(12)6-7/h2-6,11-12H,1H3/b5-3+

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	1
Optical Activity	NONE

Targets

Primary Target	Pharmacology	Potency
Sucrase-isomaltase 5 Target ID: CHEMBL3114 Sources: https://www.ncbi.nlm.nih.gov/pubmed/20378981	Inhibitor 8297	1.5 mM [IC50]
Protein tyrosine kinase 1 Target ID: Protein tyrosine kinase Sources: https://www.ncbi.nlm.nih.gov/pubmed/1423745	Inhibitor 8297
Ornithine decarboxylase 15 Target ID: CHEMBL1869 Sources: https://www.ncbi.nlm.nih.gov/pubmed/1423745	Inhibitor 8297

PubMed

Title	Date	PubMed
Hydroxylated aromatic inhibitors of HIV-1 integrase.	1995 Oct 13	7473544
Activity of caffeic acid derivatives against Candida albicans biofilm.	2014 Mar 15	24582984
In vitro anticancer activity of methyl caffeate isolated from Solanum torvum Swartz. fruit.	2015 Dec 5	26415618
K20E, an oxidative-coupling compound of methyl caffeate, exhibits anti-angiogenic activities through down-regulations of VEGF and VEGF receptor-2.	2015 Jan 15	25481497

Patents

Substance Class	Chemical Created by `admin` on `Fri Dec 15 17:50:48 UTC 2023` Edited by `admin` on `Fri Dec 15 17:50:48 UTC 2023`
Record UNII	N79173B9HF
Record Status	`Validated (UNII)`
Record Version

Name

Type

Language

CAFFEIC ACID METHYL ESTER

Common Name

English

METHYL CAFFEATE

Common Name

English

CINNAMIC ACID, 3,4-DIHYDROXY-, METHYL ESTER

Systematic Name

English

METHYL-3,4-DIHYDROXY CINNAMATE

Common Name

English

Code System Code Type Description

EPA CompTox

DTXSID401030290