Zovaglutide

Approval Year

Substance Class	Protein Created by `admin` on `Wed Apr 02 20:56:28 GMT 2025` Edited by `admin` on `Wed Apr 02 20:56:28 GMT 2025`
Protein Type	PEPTIDE
Protein Sub Type
Sequence Type	COMPLETE
Record UNII	N4XW95YF6H
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

Zovaglutide

Official Name

English

7-37-Glucagon-like peptide 1 [8-(2-methylalanine),26-[N6-[N-(17-carboxy-1-oxoheptadecyl)-L-?-glutamyl-2-[2-(2-aminoethoxy)ethoxy]acetyl-2-[2-(2-aminoethoxy)ethoxy]acetyl]-L-lysine],36-glycine] (human) fusion protein with peptide [39-[N6-[N-(17-carboxy-1-

Preferred Name

English

glucagon-like peptide 1(7-37) [human GLP-1(7-37)] (1-31), (A8>2-MeAla2, G22>E16, K34>R28, R36>G30)-variant, fused to the artificial 40-peptide (GAQP)9GQKP (32-71), su

Common Name

English

zovaglutide [INN]

Common Name

English

Code System Code Type Description

CAS

3013543-64-8

Created by admin on Wed Apr 02 20:56:28 GMT 2025 , Edited by admin on Wed Apr 02 20:56:28 GMT 2025

PRIMARY

INN

13496

Created by admin on Wed Apr 02 20:56:28 GMT 2025 , Edited by admin on Wed Apr 02 20:56:28 GMT 2025

PRIMARY

FDA UNII

N4XW95YF6H

Created by admin on Wed Apr 02 20:56:28 GMT 2025 , Edited by admin on Wed Apr 02 20:56:28 GMT 2025

PRIMARY

Related Record Type Details


					EF38T7N5MI

GLUCAGON-LIKE PEPTIDE 1 RECEPTOR

TARGET -> AGONIST

Amount:

Related Record Type Details


					N4XW95YF6H

Zovaglutide

ACTIVE MOIETY

Amount:

Structural Modifications

Modification Type	Location Site	Location Type	Residue Modified	Extent	Fragment Name	Fragment Approval
AMINO_ACID_SUBSTITUTION	[1_20] [1_70]	SITE_SPECIFIC	K		Zovaglutide modified lysine	WY4JV5K93D
AMINO_ACID_SUBSTITUTION	[1_2]	SITE_SPECIFIC	A		.ALPHA.-AMINOISOBUTYRIC ACID	1E7ZW41IQU

Name	Property Type	Amount	Referenced Substance	Defining	Parameters	References
Molecular Formula	CHEMICAL
MOL_WEIGHT:NUMBER(CALCULATED)	CHEMICAL