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Approval Year

Unknown
149124
Substance Class Protein
Created
by admin
on Mon Mar 31 21:49:54 GMT 2025
Edited
by admin
on Mon Mar 31 21:49:54 GMT 2025
Protein Type MONOCLONAL ANTIBODY
Protein Sub Type FAB
Sequence Origin HUMANIZED MOUSE
Sequence Type COMPLETE
Record UNII
N4606MB5HM
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
dapirolizumab pegol [INN]
Preferred Name English
DAPIROLIZUMAB PEGOL
INN   WHO-DD  
INN  
Official Name English
CDP-7657
Common Name English
Dapirolizumab pegol [WHO-DD]
Common Name English
IMMUNOGLOBULIN FAB' G1-KAPPA PEGYLATED, ANTI-(HOMO SAPIENS CD40LG (CD40 LIGAND, CD40L, TUMOR NECROSIS FACTOR LIGAND SUPERFAMILY MEMBER 5, TNFSF5, TUMOR NECROSIS FACTOR RELATED ACTIVATION PROTEIN, TRAP, CD154)), PEGYLATED HUMANIZED MONOCLONAL ANTIBODY
Common Name English
Code System Code Type Description
INN
9869
Created by admin on Mon Mar 31 21:49:54 GMT 2025 , Edited by admin on Mon Mar 31 21:49:54 GMT 2025
PRIMARY
NCI_THESAURUS
C174737
Created by admin on Mon Mar 31 21:49:54 GMT 2025 , Edited by admin on Mon Mar 31 21:49:54 GMT 2025
PRIMARY
SMS_ID
100000171736
Created by admin on Mon Mar 31 21:49:54 GMT 2025 , Edited by admin on Mon Mar 31 21:49:54 GMT 2025
PRIMARY
EVMPD
SUB185344
Created by admin on Mon Mar 31 21:49:54 GMT 2025 , Edited by admin on Mon Mar 31 21:49:54 GMT 2025
PRIMARY
FDA UNII
N4606MB5HM
Created by admin on Mon Mar 31 21:49:54 GMT 2025 , Edited by admin on Mon Mar 31 21:49:54 GMT 2025
PRIMARY
CAS
1416147-64-2
Created by admin on Mon Mar 31 21:49:54 GMT 2025 , Edited by admin on Mon Mar 31 21:49:54 GMT 2025
PRIMARY
From To
1_22 1_95
1_145 1_201
2_23 2_88
2_134 2_194
1_221 2_214
Related Record Type Details
CD40 LIGAND SOLUBLE
TARGET -> INHIBITOR
CD40 LIGAND RECOMBINANT
TARGET -> INHIBITOR
Related Record Type Details
DAPIROLIZUMAB PEGOL
ACTIVE MOIETY

Structural Modifications

Modification Type Location Site Location Type Residue Modified Extent Fragment Name Fragment Approval
PEGYLATION [1_227] Cys METHOXY PEG-20 77U9H6E11K
Name Property Type Amount Referenced Substance Defining Parameters References
MOL_WEIGHT:NUMBER(CALCULATED) CHEMICAL
Molecular Formula CHEMICAL
NIH
NCATS
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