U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

Details

Stereochemistry ACHIRAL
Molecular Formula C7H3Cl2N
Molecular Weight 172.011
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of DICHLOBENIL

SMILES

ClC1=CC=CC(Cl)=C1C#N

InChI

InChIKey=YOYAIZYFCNQIRF-UHFFFAOYSA-N
InChI=1S/C7H3Cl2N/c8-6-2-1-3-7(9)5(6)4-10/h1-3H

HIDE SMILES / InChI

Molecular Formula C7H3Cl2N
Molecular Weight 172.011
Charge 0
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Approval Year

PubMed

PubMed

TitleDatePubMed
Mechanisms of permanent loss of olfactory receptor neurons induced by the herbicide 2,6-dichlorobenzonitrile: effects on stem cells and noninvolvement of acute induction of the inflammatory cytokine IL-6.
2013-11-01
Balamuthia mandrillaris: staining properties of cysts and trophozoites and the effect of 2,6-dichlorobenzonitrile and calcofluor white on encystment.
2011-04-06
Habituation to thaxtomin A in hybrid poplar cell suspensions provides enhanced and durable resistance to inhibitors of cellulose synthesis.
2010-12-10
Mechanisms of olfactory toxicity of the herbicide 2,6-dichlorobenzonitrile: essential roles of CYP2A5 and target-tissue metabolic activation.
2010-11-15
Expression of transient receptor potential channel vanilloid (TRPV) 1–4, melastin (TRPM) 5 and 8, and ankyrin (TRPA1) in the normal and methimazole-treated mouse olfactory epithelium.
2010-11
Alignment between PIN1 polarity and microtubule orientation in the shoot apical meristem reveals a tight coupling between morphogenesis and auxin transport.
2010-10-19
The phenolic profile of maize primary cell wall changes in cellulose-deficient cell cultures.
2010-10
Unraveling the biochemical and molecular networks involved in maize cell habituation to the cellulose biosynthesis inhibitor dichlobenil.
2010-09
Development of a multiresidue method for the determination of multiclass pesticides in soil using GC.
2010-08
Transplantation of neural stem cells in anosmic mice.
2010-06
TRICHOME BIREFRINGENCE and its homolog AT5G01360 encode plant-specific DUF231 proteins required for cellulose biosynthesis in Arabidopsis.
2010-06
Plasticity of xyloglucan composition in bean (Phaseolus vulgaris)-cultured cells during habituation and dehabituation to lethal concentrations of dichlobenil.
2010-05
Callose implication in stomatal opening and closure in the fern Asplenium nidus.
2010-05
Permeation of herbicidal dichlobenil from a Casoron formulation through nitrile gloves.
2010-02
Degrader density determines spatial variability of 2,6-dichlorobenzamide mineralisation in soil.
2010-01
The role of callose in guard-cell wall differentiation and stomatal pore formation in the fern Asplenium nidus.
2009-12
Habituation and dehabituation to dichlobenil: simply the equivalent of Penélope's weaving and unweaving process?
2009-11
Competitive biodegradation of dichlobenil and atrazine coexisting in soil amended with a char and citrate.
2009-11
Identification of the cellulose synthase genes from the Oomycete Saprolegnia monoica and effect of cellulose synthesis inhibitors on gene expression and enzyme activity.
2009-10
The most-probable-number enumeration of dichlobenil and 2,6-dichlorobenzamide (BAM) degrading microbes in Finnish aquifers.
2009-09
High peroxidase activity and stable changes in the cell wall are related to dichlobenil tolerance.
2009-08-15
Toxicological study of pesticides in air and precipitations of Paris by means of a bioluminescence method.
2009-06
Microtubule involvement in the deposition of radial fibrillar callose arrays in stomata of the fern Asplenium nidus L.
2009-06
Human cord blood CD133+ stem cells transplanted to nod-scid mice provide conditions for regeneration of olfactory neuroepithelium after permanent damage induced by dichlobenil.
2009-04
Novel type II cell wall architecture in dichlobenil-habituated maize calluses.
2009-02
A methodology to determine pesticides pollution sources in water catchments: study case (Belgium).
2009
Thaxtomin A affects CESA-complex density, expression of cell wall genes, cell wall composition, and causes ectopic lignification in Arabidopsis thaliana seedlings.
2009
Sorption of polar and nonpolar aromatic compounds to four surface soils of eastern China.
2008-12
MAP20, a microtubule-associated protein in the secondary cell walls of hybrid aspen, is a target of the cellulose synthesis inhibitor 2,6-dichlorobenzonitrile.
2008-11
Relative crystallinity of plant biomass: studies on assembly, adaptation and acclimation.
2008-08-06
Microbial degradation of the benzonitrile herbicides dichlobenil, bromoxynil and ioxynil in soil and subsurface environments--insights into degradation pathways, persistent metabolites and involved degrader organisms.
2008-07
Cellulose synthesis: a complex complex.
2008-06
Habituation of bean (Phaseolus vulgaris) cell cultures to Quinclorac and analysis of the subsequent cell wall modifications.
2008-06
Site-specific adsorption of 1,3-dinitrobenzene to bacterial surfaces: a mechanism of n-pi electron-donor-acceptor interactions.
2008-05-06
Cellulose synthesis in Phytophthora infestans is required for normal appressorium formation and successful infection of potato.
2008-03
Evolution of a domain conserved in microtubule-associated proteins of eukaryotes.
2008
Antioxidant status, peroxidase activity, and PR protein transcript levels in ascorbate-deficient Arabidopsis thaliana vtc mutants.
2008
A novel, cellulose synthesis inhibitory action of ancymidol impairs plant cell expansion.
2008
Nonmotile cellulose synthase subunits repeatedly accumulate within localized regions at the plasma membrane in Arabidopsis hypocotyl cells following 2,6-dichlorobenzonitrile treatment.
2007-10
Increase in XET activity in bean (Phaseolus vulgaris L.) cells habituated to dichlobenil.
2007-08
Microbial degradation pathways of the herbicide dichlobenil in soils with different history of dichlobenil-exposure.
2007-07
Cellulose biosynthesis pathway is a potential target in the improved treatment of Acanthamoeba keratitis.
2007-05
[Toward a better knowledge of the pesticides used by municipality in rural society: example of Limousin Region (France)].
2007-04
Cortical microtubule arrays undergo rotary movements in Arabidopsis hypocotyl epidermal cells.
2007-02
Demonstrating formation of potentially persistent transformation products from the herbicides bromoxynil and ioxynil using liquid chromatography-tandem mass spectrometry (LC-MS/MS).
2007-02
Degradation of the herbicide dichlobenil and its metabolite BAM in soils and subsurface sediments.
2007-01-30
Cellulose synthesis is required for deposition of reticulate wall ingrowths in transfer cells.
2007-01
A mutation in At-nMat1a, which encodes a nuclear gene having high similarity to group II intron maturase, causes impaired splicing of mitochondrial NAD4 transcript and altered carbon metabolism in Arabidopsis thaliana.
2006-06
GC-MS analysis of dichlobenil and its metabolites in groundwater.
2005-11-15
Characterization of olfactory deficits in the rat following administration of 2,6-dichlorobenzonitrile (dichlobenil), 3,3'-iminodipropionitrile, or methimazole.
1996-01
Patents
Substance Class Chemical
Created
by admin
on Mon Mar 31 19:42:52 GMT 2025
Edited
by admin
on Mon Mar 31 19:42:52 GMT 2025
Record UNII
N42NR4196R
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
DICHLOBENIL
HSDB   ISO   MI  
Common Name English
NSC-521490
Preferred Name English
DICHLOBENIL [HSDB]
Common Name English
DICHLOBENIL [ISO]
Common Name English
DICHLOBENIL [MI]
Common Name English
2,6-DICHLOROBENZONITRILE
Systematic Name English
Classification Tree Code System Code
EPA PESTICIDE CODE 27401
Created by admin on Mon Mar 31 19:42:52 GMT 2025 , Edited by admin on Mon Mar 31 19:42:52 GMT 2025
Code System Code Type Description
FDA UNII
N42NR4196R
Created by admin on Mon Mar 31 19:42:52 GMT 2025 , Edited by admin on Mon Mar 31 19:42:52 GMT 2025
PRIMARY
WIKIPEDIA
2,6-DICHLOROBENZONITRILE
Created by admin on Mon Mar 31 19:42:52 GMT 2025 , Edited by admin on Mon Mar 31 19:42:52 GMT 2025
PRIMARY
NSC
521490
Created by admin on Mon Mar 31 19:42:52 GMT 2025 , Edited by admin on Mon Mar 31 19:42:52 GMT 2025
PRIMARY
CHEBI
943
Created by admin on Mon Mar 31 19:42:52 GMT 2025 , Edited by admin on Mon Mar 31 19:42:52 GMT 2025
PRIMARY
PUBCHEM
3031
Created by admin on Mon Mar 31 19:42:52 GMT 2025 , Edited by admin on Mon Mar 31 19:42:52 GMT 2025
PRIMARY
MERCK INDEX
m4322
Created by admin on Mon Mar 31 19:42:52 GMT 2025 , Edited by admin on Mon Mar 31 19:42:52 GMT 2025
PRIMARY Merck Index
CAS
1194-65-6
Created by admin on Mon Mar 31 19:42:52 GMT 2025 , Edited by admin on Mon Mar 31 19:42:52 GMT 2025
PRIMARY
EPA CompTox
DTXSID5032365
Created by admin on Mon Mar 31 19:42:52 GMT 2025 , Edited by admin on Mon Mar 31 19:42:52 GMT 2025
PRIMARY
ALANWOOD
dichlobenil
Created by admin on Mon Mar 31 19:42:52 GMT 2025 , Edited by admin on Mon Mar 31 19:42:52 GMT 2025
PRIMARY
MESH
C055869
Created by admin on Mon Mar 31 19:42:52 GMT 2025 , Edited by admin on Mon Mar 31 19:42:52 GMT 2025
PRIMARY
ECHA (EC/EINECS)
214-787-5
Created by admin on Mon Mar 31 19:42:52 GMT 2025 , Edited by admin on Mon Mar 31 19:42:52 GMT 2025
PRIMARY
HSDB
312
Created by admin on Mon Mar 31 19:42:52 GMT 2025 , Edited by admin on Mon Mar 31 19:42:52 GMT 2025
PRIMARY
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