Details
| Stereochemistry | ABSOLUTE |
| Molecular Formula | C12H22O11 |
| Molecular Weight | 342.2965 |
| Optical Activity | UNSPECIFIED |
| Defined Stereocenters | 10 / 10 |
| E/Z Centers | 0 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
OC[C@H]1O[C@@H](OC[C@H]2O[C@@H](O)[C@H](O)[C@@H](O)[C@@H]2O)[C@H](O)[C@@H](O)[C@@H]1O
InChI
InChIKey=DLRVVLDZNNYCBX-LIZSDCNHSA-N
InChI=1S/C12H22O11/c13-1-3-5(14)8(17)10(19)12(23-3)21-2-4-6(15)7(16)9(18)11(20)22-4/h3-20H,1-2H2/t3-,4-,5-,6-,7+,8+,9-,10-,11-,12-/m1/s1
| Molecular Formula | C12H22O11 |
| Molecular Weight | 342.2965 |
| Charge | 0 |
| Count |
|
| Stereochemistry | ABSOLUTE |
| Additional Stereochemistry | No |
| Defined Stereocenters | 10 / 10 |
| E/Z Centers | 0 |
| Optical Activity | UNSPECIFIED |
Approval Year
PubMed
| Title | Date | PubMed |
|---|---|---|
| Adjuvant potential of archaeal synthetic glycolipid mimetics critically depends on the glyco head group structure. | 2008-07 |
|
| Inhibition of cell-mediated lympholysis by cloned and uncloned lines of natural killer cells and cytotoxic T lymphocytes with sugars and lectins. | 1984-10-01 |
|
| The effect of unphosphorylated and phosphorylated sugar moieties on human and mouse natural killer cell activity: is there selective inhibition at the level of target recognition and lytic acceptor site? | 1983-08 |
|
| Inhibition of spontaneous but not antibody-dependent cell-mediated cytotoxicity by simple sugars: evidence that endogenous lectins may mediate spontaneous cell-mediated cytotoxicity. | 1981-09 |
Sample Use Guides
Ten to twenty million normal peripheral blood mononuclear cells were incubated with 100 u./ml interferon at 37 Celcius degrees for either 2 or 16 hr. After washing, target cells (colon tumor cell line or K-562 cells) were added and incubated for 18 h, using 75 mM of beta-gentiobiose and 1: 1, 2 5: 1, 5: 1, 7 5: 1, 10: 1, 17 5: 1, 25:1, 37-5: 1 and 50: 1. beta-Gentiobiose inhibited spontaneous cell-mediated cytotoxicity by 50% in Chang cell line cells at a 50: killer to target cell ratio and by 75% in K-562 cells at a 50:1 killer to target cell ratio.
| Substance Class |
Chemical
Created
by
admin
on
Edited
Mon Mar 31 20:33:23 GMT 2025
by
admin
on
Mon Mar 31 20:33:23 GMT 2025
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| Record UNII |
N2VA1H3TIQ
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| Record Status |
Validated (UNII)
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| Record Version |
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m5701
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PRIMARY | Merck Index | ||
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DTXSID501317544
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441422
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5996-00-9
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N2VA1H3TIQ
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admin on Mon Mar 31 20:33:23 GMT 2025 , Edited by admin on Mon Mar 31 20:33:23 GMT 2025
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PRIMARY |