BUTIDRINE

Details

Stereochemistry	UNKNOWN
Molecular Formula	C16H25NO
Molecular Weight	247.3758
Optical Activity	UNSPECIFIED
Defined Stereocenters	0 / 2
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

CCC(C)NCC(O)C1=CC2=C(CCCC2)C=C1

InChI

InChIKey=GVNYSERWAKVROD-UHFFFAOYSA-N

InChI=1S/C16H25NO/c1-3-12(2)17-11-16(18)15-9-8-13-6-4-5-7-14(13)10-15/h8-10,12,16-18H,3-7,11H2,1-2H3

HIDE SMILES / InChI

Molecular Formula	C16H25NO
Molecular Weight	247.3758
Charge	0
Count

Stereochemistry	MIXED
Additional Stereochemistry	No
Defined Stereocenters	0 / 2
E/Z Centers	0
Optical Activity	UNSPECIFIED

Description
Sources: https://www.ncbi.nlm.nih.gov/pubmed/4146153 | https://www.ncbi.nlm.nih.gov/pubmed/4392359 | https://www.ncbi.nlm.nih.gov/pubmed/35031 |

Butidrine is naphthalenemethanol devivative with β-adrenolytic, antiarrhythmic, and local anesthetic properties having sympatholytic and antiarrhythmic effects comparable to those of pronethalol and propranolol.

Originator

Approval Year

PubMed

Title	Date	PubMed
[Modifications of the electric activity of the guinea pig myocardial fiber induced by 4 stereoisomers of butidrine, a new compound with adrenergic beta receptor blockading action].	1970-01	4392359

Patents

Substance Class	Chemical Created by `admin` on `Mon Mar 31 18:20:54 GMT 2025` Edited by `admin` on `Mon Mar 31 18:20:54 GMT 2025`
Record UNII	N2S0PKP5L5
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

BUTIDRINE

Official Name

English

CO-405

Preferred Name

English

Butidrine [WHO-DD]

Common Name

English

butidrine [INN]

Common Name

English

.ALPHA.-((SEC-BUTYLAMINO)METHYL)-5,6,7,8-TETRAHYDRO-2-NAPHTHALENE-METHANOL

Systematic Name

English

CO 405

Code

English

Classification Tree Code System Code

NCI_THESAURUS

C72900