U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

Approval Year

Substance Class Protein
Created
by admin
on Sat Dec 16 14:45:48 GMT 2023
Edited
by admin
on Sat Dec 16 14:45:48 GMT 2023
Protein Type MONOCLONAL ANTIBODY CONJUGATE
Protein Sub Type IGG1
Sequence Origin HUMAN
Sequence Type COMPLETE
Record UNII
N2Q7V645PL
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
Oberotatug Ravtansine
INN  
Official Name English
oberotatug ravtansine [INN]
Common Name English
Gamma1 heavy chain Homo sapiens (1-448) [VH (Homo sapiens IGHV3-15*01 (98.0%) -(IGHD) -IGHJ4*01 (100%), CDR-IMGT [8.10.10] (26-33.51-60.99-108)) (1-119) -Homo sapiens IGHG1*03v, G1m3>G1m17, nG1m1 CH1 K120, CH3 E12, M14( CH1 R120>K (216) (120-217), hinge
Common Name English
Immunoglobulin G1-kappa, anti-[Homo sapiens LY75 (human lymphocyte antigen 75, C-type lectin domain family 13 member B, CLEC13B, DEC-205, CD205)], Homo sapiens monoclonal antibody; conjugated to maytansinoid DM4
Common Name English
Code System Code Type Description
FDA UNII
N2Q7V645PL
Created by admin on Sat Dec 16 14:45:48 GMT 2023 , Edited by admin on Sat Dec 16 14:45:48 GMT 2023
PRIMARY
NCI_THESAURUS
C199080
Created by admin on Sat Dec 16 14:45:48 GMT 2023 , Edited by admin on Sat Dec 16 14:45:48 GMT 2023
PRIMARY
CAS
2641919-35-7
Created by admin on Sat Dec 16 14:45:48 GMT 2023 , Edited by admin on Sat Dec 16 14:45:48 GMT 2023
PRIMARY
INN
12296
Created by admin on Sat Dec 16 14:45:48 GMT 2023 , Edited by admin on Sat Dec 16 14:45:48 GMT 2023
PRIMARY
From To
1_22 1_98
1_146 1_202
1_222 2_222
1_228 2_228
1_231 3_214
1_263 1_323
1_369 1_427
2_22 2_98
2_146 2_202
2_231 4_214
2_263 2_323
2_369 2_427
3_23 3_88
3_134 3_194
4_23 4_88
4_134 4_194
Related Record Type Details
CONJUGATE COMPONENT->CONJUGATE
TARGET->LIGAND
PARENT -> CONJUGATE
Related Record Type Details
ACTIVE MOIETY
Name Property Type Amount Referenced Substance Defining Parameters References
Molecular Formula CHEMICAL