Davutamig

U.S. Department of Health & Human Services Divider Arrow

National Institutes of Health Divider Arrow

NCATS

Approval Year

Substance Class	Protein Created by `admin` on `Wed Apr 02 00:11:05 GMT 2025` Edited by `admin` on `Wed Apr 02 00:11:05 GMT 2025`
Protein Type	BISPECIFIC ANTIBODY
Protein Sub Type	IGG4
Sequence Origin	HUMAN
Sequence Type	COMPLETE
Record UNII	N2H0RP6IHR
Record Status	`Validated (UNII)`
Record Version

Download

Name

Type

Language

Davutamig

Official Name

English

REGN-5093

Preferred Name

English

DAVUTAMIG [USAN]

Common Name

English

REGN5093

Code

English

davutamig [INN]

Common Name

English

Immunoglobulin G4 [229-proline], anti-(human hepatocyte growth factor receptor c-Met) (human biparatopic monoclonal REGN5093 ?4-chain) disulfide with human biparatopic monoclonal REGN5093 ?-chain, (227?223?),(230?226?)-bis(disulfide) with immunoglobulin

Common Name

English

REGN 5093 [WHO-DD]

Common Name

English

Code System Code Type Description

FDA UNII

N2H0RP6IHR

Created by admin on Wed Apr 02 00:11:05 GMT 2025 , Edited by admin on Wed Apr 02 00:11:05 GMT 2025

PRIMARY

USAN

KL-77

Created by admin on Wed Apr 02 00:11:05 GMT 2025 , Edited by admin on Wed Apr 02 00:11:05 GMT 2025

PRIMARY

SMS_ID

300000016960

Created by admin on Wed Apr 02 00:11:05 GMT 2025 , Edited by admin on Wed Apr 02 00:11:05 GMT 2025

PRIMARY

NCI_THESAURUS

C167188

Created by admin on Wed Apr 02 00:11:05 GMT 2025 , Edited by admin on Wed Apr 02 00:11:05 GMT 2025

PRIMARY

INN

12481

Created by admin on Wed Apr 02 00:11:05 GMT 2025 , Edited by admin on Wed Apr 02 00:11:05 GMT 2025

PRIMARY

CAS

2648058-48-2

Created by admin on Wed Apr 02 00:11:05 GMT 2025 , Edited by admin on Wed Apr 02 00:11:05 GMT 2025

PRIMARY

From	To
1_22	1_96
2_22	2_95
2_131	4_215
2_144	2_200
2_258	2_318
1_135	3_215
2_364	2_422
3_23	3_88
3_135	3_195
4_23	4_88
4_135	4_195
1_148	1_204
1_227	2_223
1_230	2_226
1_262	1_322
1_368	1_426

Glycosylation Type

HUMAN

Glycosylation Link Type	Site
N	1_298
N	2_294

Related Record Type Details


					QA085PMU8Q

HEPATOCYTE GROWTH FACTOR RECEPTOR

TARGET -> INHIBITOR

Interaction Type:

BINDING

Qualification:

Kd

Amount:

Related Record Type Details


					N2H0RP6IHR

Davutamig

ACTIVE MOIETY

Amount:

Structural Modifications

Modification Type	Location Site	Location Type	Residue Modified	Extent	Fragment Name	Fragment Approval
AMINO ACID REMOVAL	[1_448] [2_444]	C-TERMINUS			LYSINE	K3Z4F929H6

Name	Property Type	Amount	Referenced Substance	Defining	Parameters	References
MOL_WEIGHT:NUMBER(CALCULATED)	CHEMICAL
Molecular Formula	CHEMICAL