Details
| Stereochemistry | ACHIRAL |
| Molecular Formula | C32H31N3O12 |
| Molecular Weight | 649.6014 |
| Optical Activity | NONE |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
CC1=CC=C(N(CC(O)=O)CC(O)=O)C(OCCOC2=CC(=CC=C2N(CC(O)=O)CC(O)=O)C3=CC4=C(N3)C=C(C=C4)C(O)=O)=C1
InChI
InChIKey=AMHAQOBUZCQMHN-UHFFFAOYSA-N
InChI=1S/C32H31N3O12/c1-18-2-6-24(34(14-28(36)37)15-29(38)39)26(10-18)46-8-9-47-27-13-20(5-7-25(27)35(16-30(40)41)17-31(42)43)22-11-19-3-4-21(32(44)45)12-23(19)33-22/h2-7,10-13,33H,8-9,14-17H2,1H3,(H,36,37)(H,38,39)(H,40,41)(H,42,43)(H,44,45)
| Molecular Formula | C32H31N3O12 |
| Molecular Weight | 649.6014 |
| Charge | 0 |
| Count |
|
| Stereochemistry | ACHIRAL |
| Additional Stereochemistry | No |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Optical Activity | NONE |
Approval Year
PubMed
| Title | Date | PubMed |
|---|---|---|
| Intracellular calcium handling heterogeneities in intact guinea pig hearts. | 2004-02 |
|
| NMDA-evoked consumption and recovery of mitochondrially targeted aequorin suggests increased Ca2+ uptake by a subset of mitochondria in hippocampal neurons. | 2003-12-12 |
|
| Glutamate-mediated cytosolic calcium oscillations regulate a pulsatile prostaglandin release from cultured rat astrocytes. | 2003-12-01 |
|
| Effect of low [CaCl2] and high [MgCl2] cardioplegia and moderate hypothermic ischemia on myoplasmic [Ca2+] and cardiac function in intact hearts. | 2003-12 |
|
| Stretch-induced calcium sensitization of rat lymphatic smooth muscle. | 2003-12 |
|
| Diabetes and the accompanying hyperglycemia impairs cardiomyocyte calcium cycling through increased nuclear O-GlcNAcylation. | 2003-11-07 |
|
| Mitochondrial function in intact skeletal muscle fibres of creatine kinase deficient mice. | 2003-10-15 |
|
| Cardiotonic drugs differentially alter cytosolic [Ca2+] to left ventricular relationships before and after ischemia in isolated guinea pig hearts. | 2003-10-01 |
|
| Intracellular calcium homeostasis changes induced in rat spinal cord neurons by extracellular acidification. | 2003-10 |
|
| The importance of calcium in the appearance of p32, a boar sperm tyrosine phosphoprotein, during in vitro capacitation. | 2003-09-05 |
|
| Ca2+ transients of cardiomyocytes from senescent mice peak late and decay slowly. | 2003-09 |
|
| Na(+)-Ca2+ exchange function underlying contraction frequency inotropy in the cat myocardium. | 2003-08-01 |
|
| Bovine subcommissural organ displays spontaneous and synchronous intracellular calcium oscillations. | 2003-07-04 |
|
| Intracellular coupling via limiting calmodulin. | 2003-07-04 |
|
| The MKK6-p38 MAPK pathway prolongs the cardiac contractile calcium transient, downregulates SERCA2, and activates NF-AT. | 2003-07-01 |
|
| Two-photon interactions at single fluorescent molecule level. | 2003-07 |
|
| Multi-photon microscopy of cell types in the viable taste disk of the frog. | 2003-07 |
|
| SR33805, a Ca2+ antagonist with length-dependent Ca2+ -sensitizing properties in cardiac myocytes. | 2003-05 |
|
| Na+/H+ exchange inhibition with cardioplegia reduces cytosolic [Ca2+] and myocardial damage after cold ischemia. | 2003-05 |
|
| R-Ras alters Ca2+ homeostasis by increasing the Ca2+ leak across the endoplasmic reticular membrane. | 2003-04-18 |
|
| SR calcium handling and calcium after-transients in a rabbit model of heart failure. | 2003-04-01 |
|
| The effects of pH change on Ca(++) signaling and force in pregnant human myometrium. | 2003-04 |
|
| Cross-bridge kinetics modeled from myoplasmic [Ca2+] and LV pressure at 17 degrees C and after 37 degrees C and 17 degrees C ischemia. | 2003-04 |
|
| Muscarinic signaling in carcinoma cells. | 2003-03-28 |
|
| Cardiac neuronal nitric oxide synthase isoform regulates myocardial contraction and calcium handling. | 2003-03-21 |
|
| Increased Na+/H+-exchange activity is the cause of increased [Na+]i and underlies disturbed calcium handling in the rabbit pressure and volume overload heart failure model. | 2003-03-15 |
|
| [Na+]i and the driving force of the Na+/Ca2+-exchanger in heart failure. | 2003-03-15 |
|
| Creatine kinase injection restores contractile function in creatine-kinase-deficient mouse skeletal muscle fibres. | 2003-03-01 |
|
| Nucleoplasmic calcium regulation in rabbit aortic vascular smooth muscle cells. | 2003-03 |
|
| ATP-induced [Ca2+]i changes in the human corneal epithelium. | 2003-03 |
|
| Soy-derived isoflavones exert opposing actions on Guinea pig ventricular myocytes. | 2003-03 |
|
| Lead enters Rcho-1 trophoblastic cells by calcium transport mechanisms and complexes with cytosolic calcium-binding proteins. | 2003-01-15 |
|
| Effects of osmotic changes on the chemoreceptor cell of rat carotid body. | 2003-01-15 |
|
| Intracellular calcium waves accompany neutrophil polarization, formylmethionylleucylphenylalanine stimulation, and phagocytosis: a high speed microscopy study. | 2003-01-01 |
|
| Importance of Ca2+ influx by Na+/Ca2+ exchange under normal and sodium-loaded conditions in mammalian ventricles. | 2003-01 |
|
| Two-photon thermal bleaching of single fluorescent molecules. | 2003-01 |
|
| Stoichiometry of Na+-Ca2+ exchange is 3:1 in guinea-pig ventricular myocytes. | 2002-12-01 |
|
| Effects of thapsigargin on stimulation frequency--dependent changes in mitochondrial calcium in rat cardiac myocytes. | 2002-12 |
|
| Anesthetic preconditioning attenuates mitochondrial Ca2+ overload during ischemia in Guinea pig intact hearts: reversal by 5-hydroxydecanoic acid. | 2002-12 |
|
| [Effects of pituitary adenylate cyclase activating polypeptide (PACAP) on intracellular cAMP and Ca(2+) levels in common carp (Cyprinus carpio) pituitary cells in vitro]. | 2002-11 |
|
| Altered sarcoplasmic reticulum function in rat diaphragm after high-intensity exercise. | 2002-11 |
|
| In vivo monitoring of intracellular free calcium changes during uterine activation by prostaglandin f(2alpha) and oxytocin. | 2002-10-18 |
|
| Postresuscitation stunning: postfibrillatory myocardial dysfunction caused by reduced myofilament Ca2+ responsiveness after ventricular fibrillation-induced myocyte Ca2+ overload. | 2002-10 |
|
| Effect of bovine oviduct epithelial cell apical plasma membranes on sperm function assessed by a novel flow cytometric approach. | 2002-10 |
|
| Na(+)/Ca(2+) exchange in human myotubes: intracellular calcium rises in response to external sodium depletion are enhanced in DMD. | 2002-10 |
|
| Permeability changes induced by polylysines in rat spermatids. | 2002-09 |
|
| Cell lines derived from hippocampal neurons of the normal and trisomy 16 mouse fetus (a model for Down syndrome) exhibit neuronal markers, cholinergic function, and functional neurotransmitter receptors. | 2002-09 |
|
| Inhibitors of actin filament polymerisation attenuate force but not global intracellular calcium in isolated pressurised resistance arteries. | 2002-08-26 |
|
| Respiratory and limb muscle weakness induced by tumor necrosis factor-alpha: involvement of muscle myofilaments. | 2002-08-15 |
|
| Simultaneous measurements of mitochondrial NADH and Ca(2+) during increased work in intact rat heart trabeculae. | 2002-08 |
Patents
| Substance Class |
Chemical
Created
by
admin
on
Edited
Mon Mar 31 19:43:30 GMT 2025
by
admin
on
Mon Mar 31 19:43:30 GMT 2025
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| Record UNII |
N18RMK75W1
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| Record Status |
Validated (UNII)
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| Record Version |
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96314-96-4
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105060
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INDO-1
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m6270
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N18RMK75W1
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