ALMESTRONE

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National Institutes of Health Divider Arrow

NCATS

Details

Stereochemistry	ABSOLUTE
Molecular Formula	C19H24O2
Molecular Weight	284.3927
Optical Activity	UNSPECIFIED
Defined Stereocenters	5 / 5
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure of ALMESTRONE

Structure Search

SMILES

[H][C@@]12CCC(=O)[C@@]1(C)CC[C@]3([H])C4=CC=C(O)C=C4C[C@@H](C)[C@@]23[H]

InChI

InChIKey=JUAJXSMWFOFDFC-MNHDCVOLSA-N

InChI=1S/C19H24O2/c1-11-9-12-10-13(20)3-4-14(12)15-7-8-19(2)16(18(11)15)5-6-17(19)21/h3-4,10-11,15-16,18,20H,5-9H2,1-2H3/t11-,15-,16+,18-,19+/m1/s1

HIDE SMILES / InChI

Molecular Formula	C19H24O2
Molecular Weight	284.3927
Charge	0
Count

Stereochemistry	ABSOLUTE
Additional Stereochemistry	No
Defined Stereocenters	5 / 5
E/Z Centers	0
Optical Activity	UNSPECIFIED

Description
Sources: https://apps.who.int/medicinedocs/en/d/Js4895e/6.html | https://www.ncbi.nlm.nih.gov/pubmed/2326828 | https://onlinelibrary.wiley.com/doi/abs/10.1002/9780470682531.pat0450

Almestrone (7 alpha-methylestrone) is a synthetic steroidal estrogen. It is a precursor of several highly active steroidal hormones.

Approval Year

PubMed

PubMed

Title	Date	PubMed
[Synthesis of 7-alpha-methylestrone].	1967 Jan 31	5593211
Synthesis and testing of 17a beta-hydroxy-7 alpha-methyl-D-homoestra-4,16-dien-3-one: a highly potent orally active androgen.	1990 Feb	2326828

Patents

Patents

Substance Class	Chemical Created by `admin` on `Sat Dec 16 17:38:23 UTC 2023` Edited by `admin` on `Sat Dec 16 17:38:23 UTC 2023`
Record UNII	N18A31MTB0
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

ALMESTRONE

Official Name

English

NSC-134712

Code

English

almestrone [INN]

Common Name

English

3-HYDROXY-7.ALPHA.-METHYLESTRA-1,3,5(10)-TRIEN-17-ONE

Systematic Name

English

Classification Tree Code System Code

NCI_THESAURUS

C2181

Created by admin on Sat Dec 16 17:38:23 UTC 2023 , Edited by admin on Sat Dec 16 17:38:23 UTC 2023

Code System Code Type Description

INN

2952

Created by admin on Sat Dec 16 17:38:23 UTC 2023 , Edited by admin on Sat Dec 16 17:38:23 UTC 2023

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NSC

134712

Created by admin on Sat Dec 16 17:38:23 UTC 2023 , Edited by admin on Sat Dec 16 17:38:23 UTC 2023

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NCI_THESAURUS

C74404

Created by admin on Sat Dec 16 17:38:23 UTC 2023 , Edited by admin on Sat Dec 16 17:38:23 UTC 2023

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CAS

10448-96-1

Created by admin on Sat Dec 16 17:38:23 UTC 2023 , Edited by admin on Sat Dec 16 17:38:23 UTC 2023

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FDA UNII

N18A31MTB0

Created by admin on Sat Dec 16 17:38:23 UTC 2023 , Edited by admin on Sat Dec 16 17:38:23 UTC 2023

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EVMPD

SUB05346MIG

Created by admin on Sat Dec 16 17:38:23 UTC 2023 , Edited by admin on Sat Dec 16 17:38:23 UTC 2023

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EPA CompTox

DTXSID001016949

Created by admin on Sat Dec 16 17:38:23 UTC 2023 , Edited by admin on Sat Dec 16 17:38:23 UTC 2023

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WIKIPEDIA

Almestrone

Created by admin on Sat Dec 16 17:38:23 UTC 2023 , Edited by admin on Sat Dec 16 17:38:23 UTC 2023

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SMS_ID

100000087460

Created by admin on Sat Dec 16 17:38:23 UTC 2023 , Edited by admin on Sat Dec 16 17:38:23 UTC 2023

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PUBCHEM

65601

Created by admin on Sat Dec 16 17:38:23 UTC 2023 , Edited by admin on Sat Dec 16 17:38:23 UTC 2023

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ChEMBL

CHEMBL2104052

Created by admin on Sat Dec 16 17:38:23 UTC 2023 , Edited by admin on Sat Dec 16 17:38:23 UTC 2023

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Related Record Type Details


					N18A31MTB0

ACTIVE MOIETY