FLUPRANONE

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National Institutes of Health Divider Arrow

NCATS

Details

Stereochemistry	ACHIRAL
Molecular Formula	C20H24FN3O2
Molecular Weight	357.4219
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure of FLUPRANONE

Structure Search

SMILES

CC1=C(C=NN1CCO)C(=O)CCN2CCC(=CC2)C3=CC=C(F)C=C3

InChI

InChIKey=MBAQRSKEYXLLNY-UHFFFAOYSA-N

InChI=1S/C20H24FN3O2/c1-15-19(14-22-24(15)12-13-25)20(26)8-11-23-9-6-17(7-10-23)16-2-4-18(21)5-3-16/h2-6,14,25H,7-13H2,1H3

HIDE SMILES / InChI

Molecular Formula	C20H24FN3O2
Molecular Weight	357.4219
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Description
Sources: Ganellin C.R., Triggle David J., Dictionary of Pharmacological Agents, p. 584, retrieved from: https://books.google.ru/books?id=Z_mfTTIApVEC&pg=PA584&lpg=PA584&dq=FLUPRANONE&source=bl&ots=EtGIRrUGC-&sig=ACfU3U1rB3HQtUkyOB3HR4HIuiPxVzpSKA&hl=ru&sa=X&ved=2ahUKEwj6rOKek83jAhVG1qYKHcz9Bao4ChDoATABegQICRAI#v=onepage&q=FLUPRANONE&f=false

Flupranone was invented as an antihypertensive agent that has never been marketed. Information about the current use of this drug is not available.

Approval Year

PubMed

PubMed

Title	Date	PubMed
Antihypertensive agents. 3. Synthesis and antihypertensive activity of 3-(4-(p-fluoro-phenyl)-1,2,3,6-tetrahydro-1-pyridyl)-1-(1-(2-hydroxyethyl)-5-methyl-4-pyrazolyl)-1-propanone.	1971 Oct 15	5127874

Substance Class	Chemical Created by `admin` on `Sat Dec 16 15:54:49 GMT 2023` Edited by `admin` on `Sat Dec 16 15:54:49 GMT 2023`
Record UNII	N0U9G33XKT
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

FLUPRANONE

Official Name

English

flupranone [INN]

Common Name

English

3-(4-(P-FLUOROPHENYL)-3,6-DIHYDRO-1(2H)-PYRIDYL)-1-(1-(2-HYDROXYETHYL)-5-METHYLPYRAZOL-4-YL)-1-PROPANONE

Common Name

English

Classification Tree Code System Code

NCI_THESAURUS

C270

Created by admin on Sat Dec 16 15:54:49 GMT 2023 , Edited by admin on Sat Dec 16 15:54:49 GMT 2023

Code System Code Type Description

FDA UNII

N0U9G33XKT

Created by admin on Sat Dec 16 15:54:49 GMT 2023 , Edited by admin on Sat Dec 16 15:54:49 GMT 2023

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NCI_THESAURUS

C65728

Created by admin on Sat Dec 16 15:54:49 GMT 2023 , Edited by admin on Sat Dec 16 15:54:49 GMT 2023

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ChEMBL

CHEMBL2104649

Created by admin on Sat Dec 16 15:54:49 GMT 2023 , Edited by admin on Sat Dec 16 15:54:49 GMT 2023

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SMS_ID

100000080721

Created by admin on Sat Dec 16 15:54:49 GMT 2023 , Edited by admin on Sat Dec 16 15:54:49 GMT 2023

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EPA CompTox

DTXSID30865008

Created by admin on Sat Dec 16 15:54:49 GMT 2023 , Edited by admin on Sat Dec 16 15:54:49 GMT 2023

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EVMPD

SUB07733MIG

Created by admin on Sat Dec 16 15:54:49 GMT 2023 , Edited by admin on Sat Dec 16 15:54:49 GMT 2023

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PUBCHEM

219067

Created by admin on Sat Dec 16 15:54:49 GMT 2023 , Edited by admin on Sat Dec 16 15:54:49 GMT 2023

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INN

3256

Created by admin on Sat Dec 16 15:54:49 GMT 2023 , Edited by admin on Sat Dec 16 15:54:49 GMT 2023

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CAS

21686-10-2

Created by admin on Sat Dec 16 15:54:49 GMT 2023 , Edited by admin on Sat Dec 16 15:54:49 GMT 2023

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