U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

Approval Year

Unknown
149124
Substance Class Protein
Created
by admin
on Mon Mar 31 22:47:34 GMT 2025
Edited
by admin
on Mon Mar 31 22:47:34 GMT 2025
Protein Type MONOCLONAL ANTIBODY
Protein Sub Type IGG4
Sequence Origin HUMANIZED MOUSE
Sequence Type COMPLETE
Record UNII
MY9Z7GDJ8J
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
ABBV-8E12
Preferred Name English
TILAVONEMAB
INN   USAN  
Official Name English
tilavonemab [INN]
Common Name English
IMMUNOGLOBULIN G4, ANTI-(HUMAN TAU PROTEIN) (HUMAN-MUS MUSCULUS MONOCLONAL PR-1649264 .GAMMA.4-CHAIN), DISULFIDE WITH HUMAN-MUS MUSCULUS MONOCLONAL PR-1649264 .KAPPA.-CHAIN, DIMER
Systematic Name English
TILAVONEMAB [USAN]
Common Name English
C2N8E12
Code English
IMMUNOGLOBULIN G4-KAPPA, ANTI-(HOMO SAPIENS MAPT (MICROTUBULE-ASSOCIATED PROTEIN TAU, TAU)), MONOCLONAL ANTIBODYGAMMA4 HEAVY CHAIN (1-442) (VH (MUS MUSCULUS IGHV6-3*01 (91.9%)-(IGHD)-IGHJ4*01 (92.3%)/HOMO SAPIENS IGHV3-7*01 (71.4%)-(IGHD)-IGHJ4*01 (92.3%
Systematic Name English
C2N-8E12
Code English
Code System Code Type Description
SMS_ID
300000005956
Created by admin on Mon Mar 31 22:47:34 GMT 2025 , Edited by admin on Mon Mar 31 22:47:34 GMT 2025
PRIMARY
USAN
HI-128
Created by admin on Mon Mar 31 22:47:34 GMT 2025 , Edited by admin on Mon Mar 31 22:47:34 GMT 2025
PRIMARY
INN
10957
Created by admin on Mon Mar 31 22:47:34 GMT 2025 , Edited by admin on Mon Mar 31 22:47:34 GMT 2025
PRIMARY
CAS
2096513-89-0
Created by admin on Mon Mar 31 22:47:34 GMT 2025 , Edited by admin on Mon Mar 31 22:47:34 GMT 2025
PRIMARY
FDA UNII
MY9Z7GDJ8J
Created by admin on Mon Mar 31 22:47:34 GMT 2025 , Edited by admin on Mon Mar 31 22:47:34 GMT 2025
PRIMARY
NCI_THESAURUS
C174727
Created by admin on Mon Mar 31 22:47:34 GMT 2025 , Edited by admin on Mon Mar 31 22:47:34 GMT 2025
PRIMARY
From To
1_22 1_98
1_142 1_198
1_256 1_316
1_362 1_420
2_22 2_98
2_142 2_198
2_256 2_316
2_362 2_420
3_23 3_92
3_138 3_198
4_23 4_92
4_138 4_198
1_129 3_218
2_129 4_218
1_221 2_221
1_224 2_224
Glycosylation Type MAMMALIAN
Glycosylation Link Type Site
N 1_292
N 2_292
Related Record Type Details
MICROTUBULE-ASSOCIATED PROTEIN TAU (PAIRED HELICAL FILAMENTS (PHF))
TARGET->INHIBITOR OF AGGREGATION
Recognizes an aggregated, extracellular form of pathological tau.
Related Record Type Details
TILAVONEMAB
ACTIVE MOIETY
Name Property Type Amount Referenced Substance Defining Parameters References
Molecular Formula CHEMICAL
MOL_WEIGHT:NUMBER(CALCULATED) CHEMICAL
NIH
NCATS
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